Clinical trials: CVA
CVA (Cerebrovascular Accident), Stroke
Differences in Treatment Characteristics and Patient and Therapist Satisfaction Between Robot Assisted Therapy and Conventional Occupational Therapy Among Individuals Post Stroke
The purpose of this study is to compare the differences in treatment characteristics and patient and therapist satisfaction, between Robot Assisted Therapy (RAT) and Conventional Occupational Therapy (COT) single session in…
- Trial name
- NCT07425158
- Testing
- Robot Assisted Therapy (RAT)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- linor kennet
Stroke (CVA) or Transient Ischemic Attack
Improve Medication Adherence Among Stroke Survivors in Rural Kentucky
To test the feasibility and promise of a combined intervention provided by community health worker (CHW) in collaboration with pharmacy technician and pharmacist to improve hypertension and long-term stroke outcomes by…
- Trial name
- I-MAS (NCT07084051)
- Testing
- I-MAS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Hend Mansoor
Atherosclerosis Occlusive Disease, Stroke (CVA) or Transient Ischemic Attack
Comparison of Eversion and Conventional Techniques in Carotid Endarterectomy
Atherosclerotic carotid artery disease is responsible for approximately 20% of strokes worldwide, and its treatment options include medical therapy, surgery, and stenting.Surgical management is prioritized over medical and stent…
- Conditions
- Atherosclerosis Occlusive Disease, Stroke (CVA) or Transient Ischemic Attack, Endarterectomy, Carotid
- Trial name
- NCT07288164
- Testing
- Carotid endarterectomy, conventional, Carotid endarterectomy, eversion
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Kastamonu University
Stroke Acute, Stroke (CVA) or Transient Ischemic Attack
Evaluating the Effect of Nurse-Led Stroke Transitional Care in Tanzania
The goal of this observational study is to assess the effects of nurse-led stroke transitional care in stroke survivors, caregivers and healthcare providers who participate in nurse-led stroke transitional care program to improve…
- Trial name
- NCT07319312
- Testing
- Nurse-led stroke transitional care program
- Where
- Tanzania
- Volunteers
- 130 people
- Sponsor
- Shandong University
Cardiovascular Diseases, Cardiovascular Abnormality
Study on the Safety and Effectiveness of a Biodegradable Patent Foramen Ovale Occluder System
To evaluate the Safety and Efficacy of a Novel Biodegradable Occluder for Percutaneous Closure of Patent Foramen Ovale (PFO)
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormality, Heart Defects, Congenital, Heart Septal Defects
- Trial name
- BIOCLOSE-PFO (NCT07300358)
- Testing
- Active Comparator, Experimental
- Volunteers
- 258 people
- Sponsor
- Shanghai Lingsi Medical Technology Co., Ltd.
Stroke (CVA) or Transient Ischemic Attack
Predictive Value of Witness-derived Secondary Cincinnati Prehospital Stroke Scale Scores in Suspected Stroke
The Cincinnati Prehospital Stroke Scale (CPSS) is traditionally scored directly by a healthcare professional or a layperson who independently observes facial droop, arm weakness, and speech disturbance, constituting the primary…
- Trial name
- NCT07277790
- Where
- Turkey (Türkiye)
- Volunteers
- 235 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke (CVA) or Transient Ischemic Attack
Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors
This study aims to evaluate the effectiveness of two rehabilitation techniques-Sensory Augmentation (using mirror therapy) and Neuromodulation (using transcranial direct current stimulation, tDCS)-in improving motor recovery…
- Trial name
- NCT07266662
- Testing
- Sensory Augmentation, Neuromodulation, Combination of Sensory Augmentation and Neuromodulation
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Stroke (CVA) or Transient Ischemic Attack, Cerebral Hemorrhage
COAST Study - Cholesterol Optimization After Stroke
This study (acronym COAST Trial) is a multicenter observational registry aiming to document: patients' adherence and persistence to lipid-lowering therapy prescribed for secondary prevention; the proportion of patients achieving…
- Trial name
- COAST (NCT07256171)
- Testing
- low-fat diet, supplements, statins, ezetimibe, bempedoic acid, PCSK9 inhibitors, fibrates, or other lipid-lowering agents
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Stroke, Stroke Sequelae
Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in chronic stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT05626894
- Testing
- StrokeWear Motor and Behavioral Intervention, Usual Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke, Stroke Sequelae
A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in subacute stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT06797154
- Testing
- StrokeWear Behavioral Intervention
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Spaulding Rehabilitation Hospital
Multiple Sclerosis, Poststroke/CVA Hemiparesis
Mechanical Determinants of Upper Limbs Oscillation During Gait
It is unclear why humans typically swing their arms during gait. To date, the debate on how to arm swing comes about (i.e. whether it is caused by accelerations of the shoulder girdle or muscular activity) is still going on.
- Conditions
- Multiple Sclerosis, Poststroke/CVA Hemiparesis, Parkinson Disease, Cerebral Palsy
- Trial name
- CLAPENDAS (NCT05778474)
- Testing
- Healthy subjects, Pathologic group
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Istituto Auxologico Italiano
CVA (Cerebrovascular Accident)
A Novel, Comprehensive Approach to Post-stroke Gait Rehabilitation
The goal of this project is to determine the feasibility and optimal parameters of a novel, comprehensive approach to gait training in individuals with chronic stroke.
- Trial name
- NCT04411303
- Testing
- Step length biofeedback, Propulsive force biofeedback, Interlimb asymmetry biofeedback
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Atrial Fibrillation, Left Atrial Appendage Thrombosis
Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF
The primary objective is to demonstrate the safety and efficacy of the implantation of the LAmbre PlusTM device in patients with large or irregularly shaped appendages with non-valvular atrial fibrillation who are at increased…
- Conditions
- Atrial Fibrillation, Left Atrial Appendage Thrombosis, CVA
- Trial name
- CORRAL-AF (NCT04684212)
- Testing
- LAmbre PlusTM Left Atrial Appendage Closure System, Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)
- Where
- United States
- Sponsor
- Brian O'Neill MD
Stroke, CVA (Cerebrovascular Accident)
Cognition and Motor Learning Post-stroke
This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship.
- Trial name
- NCT04829071
- Testing
- Explicit motor learning, Implicit motor learning
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Southern California
Cerebral Vascular Accident (CVA)/Stroke
The Natural History of Recovery After Stroke
The goal of this longitudinal observational study is to learn the course of recovery after stroke. Specifically, in this study we will learn and describe the changes in cognitive, motor and sensory function over time in stroke…
- Trial name
- RESTRO (NCT06441552)
- Testing
- non-interventional
- Where
- 3 sites in Israel, Palestinian Territories
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Adi Negev-Nahalat Eran
Hemiparesis;Poststroke/CVA
Effects of Functional Electrical Stimulation Assisted Cycling in Patients With Hemiparesis After Stroke
To determine whether active cycling assisted by functional electrical stimulation (FES) Is more effective than active cycling on cardiovascular fitness in post stroke hemiparesis
- Trial name
- AVCyclES (NCT06230796)
- Testing
- FES-cycling
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UGECAM Rhône-Alpes
CVA (Cerebrovascular Accident)
Reactive Balance Training and Fitness
People with stroke should exercise to maintain function and reduce the risk of another stroke. Different types of exercise target different components of fitness, such as aerobic, strength, and balance.
- Trial name
- NCT04042961
- Testing
- Reactive balance training, Aerobic and strength training (AST)
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Toronto Rehabilitation Institute
Stroke, Hemorrhage
Q Therapeutic System for Chronic Stroke Recovery
Evaluate the effectiveness of the Q Therapeutic (BQ 3.0) System for individuals with chronic stroke in improving upper extremity function as determined by change in functional outcome measures after 3-month treatment, including…
- Conditions
- Stroke, Hemorrhage, Brain Injury, Cerebrovascular Accident (CVA)
- Trial name
- EMAGINE-C (NCT06979466)
- Testing
- Q Therapeutic System (BQ 3.0) - Active
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Burke Rehabilitation Hospital
Stroke (CVA) or TIA, Carotid Artery Plaque
[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease
This clinical trial aims to evaluate whether [¹⁸F]AlF-OC PET/MRI can characterize and quantify inflammation in carotid atherosclerotic plaques.
- Conditions
- Stroke (CVA) or TIA, Carotid Artery Plaque, Atherosclerosis Cardiovascular Disease, Carotid Arteriosclerosis
- Trial name
- NCT07104487
- Testing
- [18F]AlF-OC
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Intracranial Arteriosclerosis, Stroke (CVA) or TIA
Evaluating the Safety and Efficacy of the Maurora® DES in ICAS
The purpose of the RCT trial is to evaluate whether implantation of drug-eluting stent (DES) is more efficacious than bare metal stent (BMS) in prevention of in-stent restenosis (ISR) and improvement of outcomes for symptomatic…
- Trial name
- Maurora ICAS (NCT05719883)
- Testing
- Maurora® Sirolimus Eluting Stent System, APOLLO™ Intracranial Stent System
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital