Clinical trials: CVA
Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA)
Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation
Post-operative atrial fibrillation (POAF) is a frequent complication of surgical aortic valve replacement, affecting 38 to 63% of patients, and increasing risks of stroke, heart failure, and long-term mortality.
- Conditions
- Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA), Heart Failure, Myocardial Infarction (MI)
- Trial name
- VAGASTIMA-PILT (NCT07891390)
- Testing
- tVNS session on the left earlobe
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke, Stroke (CVA) or Transient Ischemic Attack
Neuromodulation-Enhanced Use of RObotic BALANCE Training to Improve Balance Function in Individuals With Stroke
Our proposed study, "NEUROBALANCE Stroke,"; aims to evaluate the effectiveness of a combined intervention involving robotic balance training and noninvasive brain stimulation in improving balance function and postural control in…
- Conditions
- Stroke, Stroke (CVA) or Transient Ischemic Attack, Stroke Ischemic, Stroke Gait Rehabilitation
- Trial name
- NEUROBALANCE (NCT07113041)
- Testing
- Combined (Robotic balance training and high-definition transcranial direct current stimulation), Standard of Care Balance Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kessler Foundation
Stroke Recurrence, Myocardial Infarction
Cilostazol for Prevention of Recurrent Stroke Trial
The goal of this clinical study is to learn if adding a medicine called cilostazol to usual treatment can help prevent another stroke, a heart attack, or death in patients who had a stroke caused by a blocked blood vessel, or a…
- Conditions
- Stroke Recurrence, Myocardial Infarction, Vascular Death, Ischemic Stroke
- Trial name
- Clarity (NCT07174414)
- Testing
- Cilostazol 100 mg Tablets
- Where
- 46 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Stanford University
Stroke, Acute, Stroke
Efficacy of a Telehealth Delivered Group Lifestyle Balance for People Post Stroke (tGLB-CVA)
Investigators will conduct a randomized controlled trial (RCT) to assess intervention efficacy of telehealth delivery of the GLB-CVA (tGLB-CVA) compared to a 6-month wait-list control (WLC) in partnership with a diverse group of…
- Conditions
- Stroke, Acute, Stroke, Stroke, Cardiovascular, Stroke (CVA) or TIA
- Trial name
- tGLB-CVA (NCT06569121)
- Testing
- Group Lifestyle Balance for People Post Stroke (GLB-CVA)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Baylor Research Institute
Stroke, Stroke (CVA) or Transient Ischemic Attack
Optimized Recruitment to Drive Equitable Research in Stroke, Empowering Decision-making (ORDERed)
Stroke is a major health issue, especially for women, who are more likely than men to have worse outcomes and lower quality of life after a stroke.
- Trial name
- ORDERed (NCT07576647)
- Testing
- Supported, women-centred and aphasia-friendly recruitment process (ORDERed), Traditional recruitment processes (TRADITIONAL)
- Where
- 3 sites in Canada
- Volunteers
- 1,600 people
- Sponsor
- McMaster University
Stroke, Chronic Stroke Patients
RESPARK - Brain Q for Chronic Stroke
This trial tests a promising new intervention to promote post-stroke neural reorganization and functional recovery. The Q Therapeutic (BQ 3.0) is a wearable medical system that produces and delivers non-invasive…
- Conditions
- Stroke, Chronic Stroke Patients, Cerebrovascular Accident (CVA)
- Trial name
- NCT07095920
- Testing
- Device: Q Therapeutic System (BQ 3.0) - Active
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Florida
Poststroke/CVA Hemiparesis
Comparative Effects of CIMT and TOT on Hand Function Recovery in Post Stroke Patients
This controlled clinical study investigates and compares the effectiveness of CIMT and TOT in improving hand function among post-stroke patients.
- Trial name
- NCT07764939
- Testing
- Constraint-Induced Movement Therapy, Task-Oriented Training
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Stroke, Chronic Stroke Patient
Effects of I-STROKEFIT+ on Physical Fitness Among Community-Dwelling Stroke Survivors: A Pilot RCT
This pilot randomized controlled study will evaluate whether a 12-week integrated home-based physical fitness and self-management programme (i-StrokeFit+) can improve physical fitness and physical activity among…
- Conditions
- Stroke, Chronic Stroke Patient, Stroke (6 Months or More After Onset), Community Dwelling
- Trial name
- NCT07824570
- Testing
- Physical fitness and Self-Management, Patient Education
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Teknologi Mara
Ischemic Stroke, Intracerebral Hemorrhage
Emergency Stroke Unit for Acute Cerebrovascular Events: A Prospective, Single-arm Trial With a Historical Control Group
Background Reperfusion therapies, i.e., intravenous thrombolysis (IVT) and/or endovascular thrombectomy (EVT), are most effective treatments in the management of acute ischemic stroke (AIS) patients.
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Stroke, Stroke, Acute
- Trial name
- ESU-ACE-E (NCT06728592)
- Testing
- Portable Magnetic Resonance Imaging
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- Chinese University of Hong Kong
Stroke (CVA) or TIA
Stroke Care During the COVID-19 Pandemic
Background: The SARS-CoV-2 pandemic led to substantial changes in the allocation of healthcare resources and affected the behavior of patients experiencing stroke symptoms.
- Trial name
- NCT07795021
- Testing
- statistical analysis
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 40,000 people
- Sponsor
- Dr. Yaroslav Winter
Stroke, Hemiplegia
rTMS Plus CCFES-mediated Functional Task Practice for Severe Stroke
This study is a necessary and important step in the development of a new therapy for upper limb functional recovery in patients with severe motor impairment.
- Conditions
- Stroke, Hemiplegia, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- rTMS+CCFES (NCT03870672)
- Testing
- Contralaterally Controlled Functional Electrical Stimulation, New rTMS approach, Conventional rTMS approach
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- The Cleveland Clinic
Stroke, Stroke (CVA) or TIA
Self-Supervised Constraint-Induced Movement Therapy for Stroke Recovery
The goal of this clinical trial is to learn how a partially self-supervised constraint-induced movement therapy (sCIMT) program in adults with arm and hand weakness will work after stroke.
- Conditions
- Stroke, Stroke (CVA) or TIA, Cerebral Vascular Accident (CVA)/Stroke
- Trial name
- NCT07723300
- Testing
- Self-Supervised Constraint-Induced Movement Therapy (sCIMT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ohio State University
Stroke (CVA) or Transient Ischemic Attack
Effect of HABIT-ILE on Balance and Coordination Among Stroke Patients
Strokes frequently affect motor function, balance, and coordination, reducing independence. HABIT-ILE combines upper and lower limb exercises to improve coordination and balance.
- Trial name
- NCT07754110
- Testing
- Lower Extremity HABIT-ILE GROUP A, group B Conventional treatment ( Conventional Treatment
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Intracranial Atherosclerotic Disease (ICAD), Hypertriglyceridaemia
Pemafibrate for Symptomatic ICAS RCT
The goal of this clinical trial is to learn whether pemafibrate can help prevent worsening of intracranial arterial stenosis (ICAS) in patients who have symptomatic ICAS and high triglycerides (TG) levels after ischemic stroke or…
- Conditions
- Intracranial Atherosclerotic Disease (ICAD), Hypertriglyceridaemia, Stroke (CVA) or TIA
- Trial name
- PPAR-ICAS (NCT07562178)
- Testing
- Pemafibrate
- Where
- 37 sites in Japan
- Volunteers
- 270 people
- Sponsor
- Tokyo Women's Medical University
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC
Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack
Understanding and Enhancing Human Health and Movement
By doing this study, investigators hope to learn how electrical stimulation can improve human movement, biomechanics, and function and to gather information on the safety and effectiveness of an implanted electrical stimulation…
- Conditions
- Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack, Multiple Sclerosis
- Trial name
- NCT07738978
- Testing
- Neural Prosthesis
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Louis Stokes VA Medical Center
Stroke, Stroke (CVA) or TIA
Cawthorne-Cooksey Exercises and Frenkel Exercises on Balance and Coordination in Stroke
Stroke, often caused by cerebral circulation disruption can lead to transient or permanent brain function deficit it is a leading cause of disability and death globally, with a particularly high burden in low- and middle-income…
- Conditions
- Stroke, Stroke (CVA) or TIA, Balance, Coordination Impairment
- Trial name
- NCT07724860
- Testing
- Cawthorne-Cooksey Exercises, Frenkel Exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
CVA (Cerebrovascular Accident), Stroke
Interface Pressures, Safety, Adherence, and Tactile Outcomes of Different Pressure Garments After Stroke
This study aims to investigate the interface pressure changes of single-layer with 10% circumferential reduction (S-10), single-layer with 15% circumferential reduction (S-15), and dorsal double-layered with 10% circumferential…
- Trial name
- NCT07725744
- Testing
- Single-Layered 10% Circumferential Reduction (S-10) Pressure Garment, Dorsal-Double-Layered 10% Circumferential Reduction (DD-10) Pressure Garment, Single-Layered 15% Circumferential Reduction (S-15) Pressure Garment
- Volunteers
- 33 people
- Sponsor
- National University of Malaysia
Apathy, Stroke Sequelae
Accelerated rTMS for Post-Stroke Apathy
This pilot study will investigate the safety, feasibility, tolerability, and preliminary efficacy of accelerated high-dose repetitive transcranial magnetic stimulation (rTMS) targeting the medial prefrontal cortex (mPFC) to…
- Conditions
- Apathy, Stroke Sequelae, Stroke (CVA) or TIA, Stroke/Brain Attack
- Trial name
- NCT05878457
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Medical University of South Carolina