Clinical trials: COVID-19 Pandemic
Intrusive Memories of Traumatic Event(s)
A Brief Cognitive Task Intervention for NHS Staff Affected by COVID-19 Trauma (GAINS-2 Study)
Frontline healthcare staff are frequently exposed to traumatic events at work (e.g., witnessing patients die), amplified by the COVID-19 pandemic.
- Trial name
- GAINS-2 (NCT05616676)
- Testing
- Brief digital imagery-competing task, Brief digital music-listening task, Treatment As Usual
- Where
- United Kingdom
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- P1vital Products Limited
Anxiety, COVID-19 Pandemic
SMILE: Clinical Trial to Evaluate Mindfulness as Intervention for Racial and Ethnic Populations During COVID-19
The goal of this clinical trial is to evaluate the SMILE app, a Digital Health Platform (DHP), that will deliver a mindfulness intervention, designed to mitigate COVID-19 related stress.
- Trial name
- SMILE (NCT06242080)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Depression
Mobile Health and COVID-19
The proposed research focuses on evaluating the mobile application, Easing Anxiety Sensitivity for Everyone (EASE), to improve overall public health that concerns risks and mental health status during the coronavirus disease of…
- Trial name
- NCT05074693
- Testing
- EASE app, INSIGHT (Control) App
- Where
- 2 sites in United States
- Volunteers
- 822 people, healthy volunteers welcome
- Sponsor
- University of Houston
Covid19, Anosmia
Smell in Covid-19 and Efficacy of Nasal Theophylline
Evidence of COVID-19 related anosmia and dysgeusia continues to accumulate daily. Currently, up to 80% of patients report subjective olfactory dysfunction (OD), and prevalence using objective olfactory testing could be even…
- Conditions
- Covid19, Anosmia, Olfactory Disorder, Covid-19 Pandemic
- Trial name
- SCENT2 (NCT04789499)
- Testing
- Theophylline Powder
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Washington University School of Medicine
Bulimia Nervosa, Bulimia; Atypical
Reward Re-Training: A New Treatment to Address Reward Imbalance During the COVID-19 Pandemic
In the current study, the investigators will revise our existing 10-session group RRT treatment manual to specifically address the challenges in building social support and enhancing both momentary and sustained reward during the…
- Conditions
- Bulimia Nervosa, Bulimia; Atypical, Binge Eating, Binge-Eating Disorder
- Trial name
- NCT04661410
- Testing
- Reward Re-Training, Supportive Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Drexel University
COVID-19, Pregnancy Complications
Health and Wellbeing of Pregnant and Post-Partum Women During the COVID-19 Pandemic
The purpose of this study is to assess the health and wellbeing of pregnant and recently pregnant women during the COVID-19 pandemic using an online survey.
- Conditions
- COVID-19, Pregnancy Complications, Mental Health Wellness 1, Anxiety
- Trial name
- NCT04385238
- Testing
- This is an online survey with no intervention.
- Where
- United States
- Volunteers
- 6,894 people
- Sponsor
- Pregistry
COVID-19 Vaccines, COVID-19 Pandemic
Getting to Yes, Michigan! (G2YMI)
This study entitled Community-Centered Interventions for Improved Vaccine Uptake for COVID-19 (CIVIC): Getting to Yes, Michigan!, is designed to increase vaccine uptake among populations that experience COVID-19 related…
- Trial name
- G2YMI (NCT05096260)
- Testing
- Motivational Interviewing based SMS/MMS and web content
- Where
- United States
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
COVID-19, SARS-CoV 2
COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients
Povidone-iodine (PVP-I) is a broad-spectrum antiseptic with activity against bacteria, fungi, and viruses. It has been previously used in both intranasal preparations against Methicillin Resistant Staphylococcus Aureus (MRSA) as…
- Trial name
- PIIPPI (NCT04364802)
- Testing
- Povidone-Iodine Nasal Spray and Gargle
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nikita Gupta
Covid19, Non-specific Effects of Vaccines
Using BCG to Protect Senior Citizens During the COVID-19 Pandemic
Background: The virus SARS-CoV-2 has spread rapidly throughout the world. Seniors are at high risk of severe COVID-19 when infected.
- Conditions
- Covid19, Non-specific Effects of Vaccines, Heterologous Immunity, Morbidity
- Trial name
- NCT04542330
- Testing
- BCG-Denmark, Saline
- Where
- Denmark
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Covid19
The Role of Frequent Point-of-care Molecular Workplace Surveillance for Miners
The long-term goal of the study is to mitigate the spread of the pandemic in miners, a population of high-risk, rural essential workers who are susceptible and vulnerable to COVID-19, partly based on exposure to particulate air…
- Trial name
- NCT04977050
- Testing
- Quidel quickvue antigen test for COVID-19
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
COVID19
Clinical Validation of New Injection Molded Flocked Nasopharyngeal Swabs in Response to the COVID-19 Pandemic
The SARS-CoV-2 pandemic has resulted in an international shortage of the nasopharyngeal (NP) swabs used to collect sample for virological testing.
- Trial name
- NCT04368260
- Testing
- Control swab, Prototype swab
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Virginia
COVID-19 Pandemic
Increasing COVID-19 Testing in Chicago's African American Testing Desserts
This study uses a population-based approach to increase uptake of COVID-19 testing within a highly segregated and underserved African American community in Chicago.
- Trial name
- NCT05197452
- Testing
- COVID-19 Testing
- Where
- United States
- Volunteers
- 2,167 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
COVID
Use of Convalescent Plasma for COVID-19
The plan is to transfuse COVID-19 infected patients with convalescent plasma and observe whether this will result in a significant improvement in clinical outcome in comparison to historical experience.
- Trial name
- NCT04408040
- Testing
- Convalescent Plasma
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northside Hospital, Inc.
COVID-19, Bariatric Surgery Candidate
Bariatric Surgery and COVID-19
The National Bariatric Surgical Registry (NBSR) is a prospectively collected database for all patients undergoing elective bariatric surgery in the UK.
- Trial name
- NCT05532891
- Testing
- COVID-19 pandemic
- Where
- United Kingdom
- Volunteers
- 11,545 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Psychiatric Disorder, Mental Health Disorder
Attitudes Towards Receiving Mental Health Care Using Telehealth During the Coronavirus Disease 2019 (COVID-19) Pandemic
The purpose of this study is to collect patients' experiences and feedback to better understand and improve mental health care using telehealth services.
- Conditions
- Psychiatric Disorder, Mental Health Disorder, Stress, Adjustment Disorders
- Trial name
- NCT04693052
- Testing
- No interventions
- Where
- United States
- Volunteers
- 605 people
- Sponsor
- Northwestern University
Social Emotional Wellness
Implementing and Evaluating a Social-Emotional Learning Program for Refugee Children During the COVID-19 Pandemic
The overall goal of this overall goal is to pilot an adaptation of an established Social-Emotional Learning Program with novel wellness and COVID-19 safety components that are trauma-informed and culturally-specific in a…
- Trial name
- NCT04931888
- Testing
- EMPOWER
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Yale University
Type 2 Diabetes
Social Media-Delivered Patient Education in Enhancing Type 2 Diabetics Self-Management and Attitudes During the COVID-19 Pandemic
The current study was to develop a software "Line@" based health education program, providing video-based health information and communication between diabetes patients and health-care professionals.
- Trial name
- NCT04876274
- Testing
- TMU-LOVE
- Where
- Taiwan
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
COVID-19
Coagulopathy of COVID-19: A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care
Coagulopathy of COVID-19 afflicts approximately 20% of patients with severe COVID-19 and is associated with need for critical care and death.
- Trial name
- NCT04362085
- Testing
- Therapeutic Anticoagulation
- Where
- Canada
- Volunteers
- 465 people
- Sponsor
- Unity Health Toronto
SARS-CoV-2, COVID-19
A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults
The purpose of Part A of this study is to assess the immune response and safety of a booster dose of investigational COVID-19 mRNA vaccines in healthy adults.
- Trial name
- NCT05960097
- Testing
- CV0701 mRNA COVID-19 Vaccine (Low dose), CV0701 mRNA COVID-19 Vaccine (Medium dose), CV0701 mRNA COVID-19 Vaccine (High dose)
- Where
- 17 sites in United States, Australia
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COVID-19, SARS-CoV-2
Safety and Immunogenicity Study of a Booster Dose of the Investigational CV0501 mRNA COVID-19 Vaccine in Adults at Least 18 Years Old
Prevention of COVID-19 caused by SARS-CoV-2.
- Trial name
- NCT05477186
- Testing
- CV0501 (3 μg), CV0501 (6 μg), CV0501 (12 μg)
- Where
- 17 sites in United States, Australia and 1 more
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline