Clinical trials: Brain Fog
Long COVID
DAOIB for the Treatment of Brain Fog
This is a 24-week open trial. We will enroll long-COVID patients with cognitive impairments. All patients will receive DAOIB for 24 weeks.
- Trial name
- NCT05764538
- Testing
- DAOIB
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease, Gait Disorders, Neurologic
Automated Mechanical Peripheral Stimulation to Treat Freezing of Gait in Patients With Parkinson's Disease and STN-DBS
The objective is to investigate whether AMPS (Automated Mechanical Peripheral Stimulation) is effective in reduction of FOG measured via the FOG-AC (Freezing Of Gait Assessment Course) in people with Parkinson Disease and STN-DBS…
- Trial name
- AMBITION (NCT04831879)
- Testing
- GONDOLA AMPS
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Gondola Medical Technologies SA
Compassion Fatigue, Self Efficacy
The Effects of Resilience and Self-efficacy on Nurses' Compassion Fatigue
Among healthcare providers, nursing is a stressful and compassionate profession. Nurses empathetically support patients with pain, loneliness, disease and even confronted with death in line with their critically physical, mental…
- Conditions
- Compassion Fatigue, Self Efficacy, Resilience
- Trial name
- NCT04911504
- Where
- China
- Volunteers
- 978 people
- Sponsor
- Central South University
Cognitive Reserve, Aging
Cognitive Reserve and Post-Fatigue Recovery in Older Adults
As people grow older, it is common to experience a drop in physical stamina and memory functions. This can make recovering from daily physical and mental fatigue more difficult, which directly impacts an individual's independent…
- Conditions
- Cognitive Reserve, Aging, Mental Fatigue, Fatigue
- Trial name
- NCT07667985
- Where
- Turkey (Türkiye)
- Volunteers
- 696 people, healthy volunteers welcome
- Sponsor
- Uşak University
Concentration Ability Impaired, Mental Fatigue
An Exploratory Investigation of a Supplement to Support Student Learning
In this trial, the herbal supplement (GeniusDrops) will be tested to see the effects it has on the dependent variables of interest.
- Trial name
- NCT05528094
- Testing
- GeniusDrops
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- JoySpring
Mental Fatigue, Alertness
Effect of Coffeeberry on Mood and Cognitive Performance
The primary aim of this randomised, double-blind, placebo-controlled, cross-over study is to assess the short-term cognitive effects of two beverages containing 100 and 300 mg coffeeberry extract (obtained from the fruit of the…
- Conditions
- Mental Fatigue, Alertness, Mood, Cognition
- Trial name
- NCT04975802
- Testing
- Coffeeberry, Caffeine
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Alert Fatigue, Health Personnel
Intervention Program for Alarm Fatigue in NICU Nurses Based on ABC-X Model
Monitors in newborn intensive care (NICU) help keep babies safe, but the constant beeping can overwhelm nurses. This 'alarm fatigue' makes it harder for nurses to identify real emergencies, stresses them out, and can impact…
- Trial name
- NCT07025863
- Testing
- Alarm Fatigue Intervention Program
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Guizhou Medical University
Psychological Stress, Mental Fatigue
The Role of Physical Ardor in Triggering State Anattā and Psychophysiological Recovery
This study investigates how different types of aerobic exercise-specifically continuous treadmill running versus intermittent ball games-influence mental restoration in university students.
- Conditions
- Psychological Stress, Mental Fatigue, Self-Perception, Autonomic Nervous System Function
- Trial name
- SPAR (NCT07488169)
- Testing
- Continuous Aerobic Exercise (Treadmill-based), Intermittent Aerobic Exercise (Ball Games)
- Where
- China
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Parkinson Disease, Freezing of Gait
Application of Thoracic Epidural SCS for Managing FOG in Patients With Advanced Parkinson's Disease
Spinal cord stimulation (SCS) has proven to be effective for pain that is unresponsive to medication. This technique involves an anesthesiologist or a neurosurgeon placing stimulation electrodes at the thoracic vertebrae to…
- Conditions
- Parkinson Disease, Freezing of Gait, Spinal Cord Stimulation
- Trial name
- NCT06630702
- Testing
- SCS electrode stimulation 1, SCS electrode stimulation 2, SCS electrode stimulation 3
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Parkinson Disease
Function-based Accelerated Stimulation Therapy (FAST-therapy) for Freezing of Gait (FOG) After Parkinson's Disease (PD)
Parkinson disease (PD) is a common disorder in which reduced speed of movement results from inadequate brain production of the chemical dopamine.
- Trial name
- NCT05509842
- Testing
- rTMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Mental Fatigue, Muscle Strength Dynamometer
Acute Mental Fatigue and Muscle Strength
This study will investigate the acute effects of mental fatigue on lower-extremity muscle strength and limb symmetry in healthy young adults.
- Trial name
- NCT07846618
- Testing
- Computer-Based Mental Fatigue Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Anxiety, Depression
Online Multi-component Psychological Intervention for Healthcare Workers During COVID-19 Pandemic
The objective of this study is to carry out a randomized clinical trial with healthcare workers in Mexico through a web platform.
- Conditions
- Anxiety, Depression, Sleep Disturbance, Quality of Life
- Trial name
- NCT04890665
- Testing
- Online psychological intervention for healthcare workers
- Where
- 3 sites in Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Internacional de Valencia
Red Tide, Neurologic Disorder
Investigating Health Impacts of Exposure to Harmful Algal Blooms
The goals of this project are to study the biological effects of environmental toxins (ET), in particular aquatic toxins such as brevetoxins (PbTx) and microcystin or their metabolites.
- Conditions
- Red Tide, Neurologic Disorder, Florida
- Trial name
- NCT06883227
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Roskamp Institute Inc.
Cognitive Fatigue, Mental Fatigue
Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance
This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- FRESH (NCT05011318)
- Testing
- Baseline, Fatigue Manipulation
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Diet, Healthy, Food Habits
Impact of Mindfulness Program on Perceived Wellness, Eating Habits and Relationship to Food
Mindfulness, seemingly a simple concept, research shows that the impact of mindfulness on the overall wellness of an individual can be helpful (5).
- Conditions
- Diet, Healthy, Food Habits, Mental Fatigue, Mental Stress
- Trial name
- NCT05233046
- Testing
- Nutrition and Mental health counseling, Nutrition and Mental health counseling with Nourish Carolina
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Aspire Nutrition, LLP
Attention Difficulties
Guayusa: The Effect of an Herbal Extract on Alertness and Mental Fatigue
The primary objective of this randomized, double-blind, placebo-controlled, cross-over study is to assess the acute effects of a novel ingredient, guayusa on alertness and mental fatigue compared to a placebo.
- Trial name
- NCT05530915
- Testing
- Gel capsule
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Alarm Fatigue in Intensive Care Unit Nurses, Psychological Well-Being in Intensive Care Unit Nurses
Effects of Relaxation, Mindfulness, and Breathing Therapy on Alarm Fatigue and Psychological Well-being in Intensive Care Nurses
The goal of this clinical trial is to compare the effects of the Benson Relaxation Technique, mindfulness-based stress reduction meditation, and breathing therapy on reducing alarm fatigue and improving psychological well-being…
- Trial name
- NCT07124364
- Testing
- Benson Relaxation Technique, Mindfulness-Based Stress Reduction Meditation, Breathing Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 168 people
- Sponsor
- Hacer Eroglu
Covid19, Burnout, Professional
Mental Health of Professionals Working in Pediatric Intensive Care Units During the COVID-19 Pandemic
Health professionals are extremely exposed to psychosocial risks, as they experience, in general, high levels of stress, anxiety, fatigue and suffering, due to the nature and location of their work.
- Conditions
- Covid19, Burnout, Professional, Stress Disorders, Post-Traumatic, Anxiety
- Trial name
- NCT04846907
- Testing
- Web-based survey
- Where
- Brazil
- Volunteers
- 1,148 people, healthy volunteers welcome
- Sponsor
- D'Or Institute for Research and Education
Surgical Intervention
Assessment of Surgeons' Mental Fatigue Based on Operating Time
In May 2023, the French National Authority for Health published a solution for patient safety regarding tunnel vision. This concept, which is uncommon in the medical field, is defined as any situation in which a professional's…
- Trial name
- COGNICHIR (NCT07228767)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Aneurysmal Subarachnoid Hemorrhage
Pharmaceutical Treatment of Fatigue After Aneurysmal Subarachnoid Hemorrhage
Many people who have undergone subarachnoid hemorrhage from an aneurysm (an artery of a vein in the brain) struggle with a pronounced fatigue as well as a number of other sequelae such as impaired concentration, memory deficits…
- Trial name
- NCT03209830
- Testing
- OSU 6162
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital