Clinical trials: Ankle Sprains, active
Ankle Sprains, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprains, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07728526
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bahçeşehir University
Chronic Ankle Instability, Ankle Sprain
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
This is a multicenter, randomized, controlled clinical trial comparing two surgical techniques for the treatment of chronic ankle instability (CAI).
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Joint Instability
- Trial name
- REAR (NCT07878312)
- Testing
- Arthroscopic Anterior Talofibular Ligament Repair, Internal Brace Augmentation, REGENETEN Bioinductive Collagen Scaffold
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ankle Sprains
Comparison of the Effects of Hip and Ankle Focused Progressive Exercise Training on Lower Extremity Function in Athletes With Chronic Ankle Instability
Chronic ankle instability refers to a combination of persistent mechanical and functional instability symptoms following an ankle sprain.
- Trial name
- NCT07319403
- Testing
- Gluteus Medius, Gluteus Maximus, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Ankle Sprain
Computed Tomography With Stress Maneuvers for Evaluation of Distal Tibiofibular Syndesmosis Instability (CTMETS)
The main aim of this study was to investigate which strategy can diagnose more accurately syndesmotic instability among an existing index test (ankle CT in neutral position) and two new add-on index tests (ankle CT in a stress…
- Trial name
- CTMETS (NCT04095598)
- Testing
- Comparative Ankle Tomography with Stress Maneuvers
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- Hospital Israelita Albert Einstein
Ankle Sprains, Lateral Ankle Sprain
Study of the AxisBoard Single-Leg Balance Board in Adults With Lateral Ankle Sprain
The goal of this study is to learn whether a 28-day home exercise program using the AxisBoard Single-Leg Balance Board improves ankle function in adults who are still having symptoms 6 weeks to 6 months after a lateral (outer)…
- Trial name
- NCT07860125
- Testing
- AxisBoard Single-Leg Balance Board
- Volunteers
- 80 people
- Sponsor
- DITU Inc.
Lateral Ankle Sprain
Mulligan Mobilization With Movement for Acute Lateral Ankle Sprains
This randomized controlled trial evaluates the effects and clinical specificity of Mulligan Mobilization With Movement (MWM) in adults with grade I or II lateral ankle sprains occurring less than 6 weeks before enrollment.
- Trial name
- NCT07849374
- Testing
- Mulligan Mobilization With Movement, Usual-Care Rehabilitation for Lateral Ankle Sprain
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Université Catholique de Louvain
Ankle Sprain, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprain, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07760233
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bahçeşehir University
Ankle Sprain, Lateral Ankle Sprain
Dynamic Neuromuscular Stability Exercises With and Without Rhythmic Auditory Stimulation in Lateral Ankle Sprain
To examine the effects of Dynamic Neuromuscular Stability exercises with and without Rhythmic Auditory Stimulation on balance, proprioception, and functional performance in badminton players with lateral ankle sprain.
- Conditions
- Ankle Sprain, Lateral Ankle Sprain, Lateral Ankle Instability, Dynamic Neuromuscular Stabilization (DNS)
- Trial name
- DNS (NCT07726810)
- Testing
- Dynamic Neuromuscular Stabilization with Rhythmic Auditory Stimulation, Dynamic Neuromuscular Stabilization Alone
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Ankle Sprains, Ankle Injuries and Disorders
Auditory Biofeedback Gait Training Individuals With Chronic Ankle Instability
The goal of this randomized clinical controlled trial is examine the effects of gait training with auditory biofeedback (AudFB) on gait biomechanics, clinical measures of ankle joint health, and patient-centered outcomes.
- Trial name
- NCT06868316
- Testing
- Walking, Rucking, Running
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Danielle Torp
Chronic Ankle Instability, CAI, Ankle Sprain
Ankle vs. Hip vs. Combined Strengthening in Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition that can develop after a lateral ankle sprain. Up to 40% of people who sprain their ankle experience a recurrence within a year, and as many as 30% develop persistent symptoms…
- Trial name
- SHAC (NCT07606534)
- Testing
- Isometric Ankle Strengthening Program, Hip Strengthening, Combined Isometric Ankle and Hip Strengthening Program
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- University of Liege
Ankle Sprain, Hypermobility, Joint
Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort Study
GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability.
- Trial name
- NCT06897293
- Testing
- Modified Broström procedure + Suture tape augmentation operation, Modified Broström procedure operation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Peking University Third Hospital
Ankle Sprain
Semiconductor Embedded Socks for Ankle Sprains
The goal of this clinical trial is to determine if semiconductor fabric embedded in socks can improve healing after non operative ankle sprains. The main questions it aims to answer are: 1.
- Trial name
- NCT07025733
- Testing
- Semiconductor Embedded Sock, Control Compression Sock
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Musculoskeletal Injury, Pediatrics
Topical Diclofenac vs.Oral Ibuprofen for MSK Pain in Children
The TOP-MAP pilot trial has multiple goals. The first goal of this pilot clinical trial is to find out if it will be possible to carry out a study at multiple pediatric emergency department sites (Peds ED) comparing Non-Steroidal…
- Conditions
- Musculoskeletal Injury, Pediatrics, Sprain and Strain of Ankle, Sprain Knee
- Trial name
- TOP-MAP (NCT07145645)
- Testing
- Voltaren Topical Gel, Ibuprofen Oral Suspension 100 mg/5mL, ORA-Blend Oral Suspension
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Ankle Sprains, Patellofemoral Pain Syndrome
Distinct Directional Postural Stability Deficits Across Lower Limb Musculoskeletal Disorders
Lateral ankle sprain (LAS) and patellofemoral pain syndrome (PFPS) are common musculoskeletal conditions associated with postural instability.
- Trial name
- LAS-PFPS (NCT07508163)
- Testing
- diagnosis of APSI, MLSI, OASI
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Ankle Injuries, Ankle Sprains
Ankle Instability Using Foot Intensive Rehabilitation
The overall objective of this study is to examine the effects of a 6-week foot-intensive rehabilitation (FIRE) program on lateral ankle sprain (LAS) re-injury rates, CAI symptoms, sensorimotor function, and self-reported…
- Trial name
- FIRE (NCT04493645)
- Testing
- Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Matthew Hoch
Ankle Sprain, Ankle (Ligaments); Instability (Old Injury)
Comparison of Anesthetic Techniques for Early Recovery After Ankle Arthroscopy
Ankle arthroscopy is increasingly performed as a day-case procedure, making rapid recovery and efficient discharge critical. Anesthetic technique substantially influences postoperative recovery, yet high-quality evidence…
- Conditions
- Ankle Sprain, Ankle (Ligaments); Instability (Old Injury), Pain Management, ERAS
- Trial name
- NCT07460310
- Testing
- Total intravenous anesthesia combined with peripheral nerve block (TIVA + PNB) group, General anesthesia combined with peripheral nerve block (GA + PNB) group, Spinal anesthesia
- Volunteers
- 200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Ankle Sprain, Chronic Ankle Sprains
Investigating the Effects of Cognitive Functional Therapy on Pain, Physical Function, and Kinesiophobia in Individuals With Chronic Ankle Sprain
The aim of this study is to investigate the effects of Cognitive Functional Therapy (CFT) on pain, physical function, and kinesiophobia in individuals with chronic ankle sprain (CAS).
- Trial name
- NCT07449078
- Testing
- Cognitive Functional Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University
Ankle Sprain
the Efficacy of Hyperbaric Oxygen on Acute Ankle Sprain
Investigators recruited 208 patients with acute ankle sprain who were from the Rehabilitation Department of the Second Affiliated Hospital of Zhejiang University, School of Medicine from January 2026 to November 2028.
- Trial name
- NCT07405281
- Testing
- hyperbaric oxygen therapy, non Hyperbaric Oxygen Therapy
- Volunteers
- 208 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Young Football Players, Ankle Sprain Prevention
Comparison Interventions on Kinetic and Kinematic Parameters
Currently, it is difficult to find studies in the literature comparing proprioception exercises with the effect of manual therapy on improving balance, and in the long run it may translate into improved activity, functionality…
- Trial name
- Balance (NCT07326475)
- Testing
- Manual therapy, Exercise
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Ankle Sprain
NMES With PNF for Ankle Sprain Rehabilitation
Ankle sprains are one of the most common sports injuries. In some people, they can lead to chronic ankle problems that affect daily life and sports performance.
- Trial name
- NCT07190599
- Testing
- Proprioceptive neuromuscular facilitation (PNF) with neuromuscular electrical stimulation (NMES), Proprioceptive neuromuscular facilitation (PNF) only
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fooyin University