Clinical trials: Acute Myocardial Infarction (AMI)
Diabetes Mellitus, Type 2, Myocardial Infarction
GLP-1RAs) and SGLT2is Combination Therapy and MACEs in Patients with Type 2 Diabetes.
Management of type 2 diabetes mellitus (T2DM) has evolved from a glucocentric to a cardiometabolic approach. Both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) reduce…
- Trial name
- NCT06017544
- Testing
- PCI
- Where
- Italy
- Volunteers
- 257 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cardiovascular Diseases, Coronary Disease
Intravenous Streptokinase in Acute Myocardial Infarction
To determine whether the administration of intravenous streptokinase (SK) early in the course of acute, transmural myocardial infarction would limit myocardial damage.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000507
- Testing
- streptokinase
- Sponsor
- University of Washington
Acute Myocardial Infarction
Efficacy of Early Home-based Cardiac Rehabilitation Program for Patients After Acute Myocardial Infarction
The purpose of this study was to evaluate the effect of this CR program on the improvement of myocardial function using the three-dimensional speckle tracking echocardiography (3D-STE) in AMI patients.
- Trial name
- NCT02584192
- Testing
- entailing an early home-based CR program, enter the usual care program
- Volunteers
- 52 people
- Sponsor
- Lin Xu
Nonfatal Myocardial Infarction, Coronary Death
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Heart Disease Death
The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and…
- Trial name
- NCT01360073
- Where
- 2 sites in Spain, Sweden
- Volunteers
- 42,542 people
- Sponsor
- AstraZeneca
Acute ST-elevation Myocardial Infarction
the Effect of Prolonged Inflation Time During Stents Deployment for ST-elevation Myocardial Infarction
The purpose of this study is to determine whether prolonged inflation time on drug-eluting stents deployment for ST-elevation myocardial Infarction was better than conventional stents deployment.
- Trial name
- NCT03199014
- Testing
- deploying the Drug-eluting Stents with a prolonged time, deploying the Drug-eluting Stents with a conventional time
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Coronary Heart Disease, Acute Myocardial Infarction
Twenty-year Follow-up of the Inter99 Cohort
Being born small increases your risk of developing Type 2 diabetes (T2D) with age. Furthermore, data even suggest that some of the diseases ("complications") in the eyes, kidneys, nerves, liver, blood vessels and heart often seen…
- Conditions
- Coronary Heart Disease, Acute Myocardial Infarction, Cardiovascular Diseases, Type 2 Diabetes
- Trial name
- NCT05166447
- Where
- Denmark
- Volunteers
- 4,000 people
- Sponsor
- Bispebjerg Hospital
Multi Organ Failure, Left Ventricular Dysfunction
Acute Cardiac Dysfunction in Critical Illnes
The overall aim of the study is to establish the clinical importance of cardiac dysfunction, by estimating its incidence and impact on short- and long-term outcomes, in a mixed population of critically ill patients with…
- Conditions
- Multi Organ Failure, Left Ventricular Dysfunction, Right Ventricular Dysfunction, Tako Tsubo Cardiomyopathy
- Trial name
- NCT05860504
- Testing
- Echocardiography, Cardiac magnetic resonance imaging, Coronary CT
- Where
- Sweden
- Volunteers
- 592 people
- Sponsor
- Sahlgrenska University Hospital
Nonfatal Myocardial Infarction, Coronary Death
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death
The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and…
- Trial name
- NCT01360047
- Where
- Spain
- Volunteers
- 39,513 people
- Sponsor
- AstraZeneca
Reperfused Acute Myocardial Infarction
Trial of Hematopoietic Stem Cells in Acute Myocardial Infarction
The aim of this study is to compare the effectiveness of four different strategies for preventing the ventricular postinfarction remodelling: 1) Conventional treatment for reperfunded extensive acute myocardial infarction, 2)…
- Trial name
- TECAM2 (NCT00984178)
- Testing
- Granulocite Colony Stimulating Factor treatment (G-CSF), Bone marrow mononuclear cells
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- TECAM Group
Myocardial Infarction, ST Elevation Myocardial Infarction
10-Years Follow-up of the EXAMINATION Trial
The EXAMINATION trial was a superiority trial that compared everolimus-eluting stents (EES) versus bare-metal stents (BMS) in an all-comer ST-segment elevation myocardial infarction (STEMI) population.
- Conditions
- Myocardial Infarction, ST Elevation Myocardial Infarction, Infarction, Necrosis
- Trial name
- EXAMINAT10N (NCT04462315)
- Testing
- Everolimus Eluting Coronary Stent System, Cobalt chromium balloon expandable stent (non-drug-eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,498 people
- Sponsor
- Hospital Clinic of Barcelona
ST Segment Elevation Myocardial Infarction
DANish Study of Optimal Acute Treatment of Patients With ST-elevation Myocardial Infarction
This study focuses on Cardioprotective strategies.
- Trial name
- DANAMI-3 (NCT01435408)
- Testing
- Conventional primary PCI, Ischemic postconditioning., Deferred stenting in primary PCI.
- Where
- 5 sites in Denmark
- Volunteers
- 2,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Myocardial Infarction, Acute Coronary Syndrome
Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes
Type 2 diabetes mellitus (T2DM) is one of the most important risk factors for atherosclerotic heart disease. Strategies focused solely on glycemic control have failed to demonstrate vascular events reduction in this population.
- Conditions
- Myocardial Infarction, Acute Coronary Syndrome, Diabetes, Ventricular Dysfunction
- Trial name
- NCT06286878
- Testing
- Dapagliflozin
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- University of Sao Paulo
Acute Coronary Syndrome, STEMI
Efficacy and Safety of Individualized P2Y12 Receptor Antagonists Treatment Based on Agregometry Versus Fixed Dose Regimen in Patients After Acute Myocardial Infarction
The specific goal of this study is to determine whether the individualized approach and adjusting the dosage of the P2Y12 receptor inhibitors will improve the platelet inhibiton and the clinical outcome in patients with an ACS…
- Conditions
- Acute Coronary Syndrome, STEMI, NSTEMI - Non-ST Segment Elevation MI, PLATELET AGGREGATION
- Trial name
- SPARELIFE (NCT04369534)
- Testing
- Clopidogrel, Ticagrelor
- Where
- Croatia
- Volunteers
- 120 people
- Sponsor
- University of Zagreb
ST-segment Elevation Myocardial Infarction, Left Ventricular Remodeling
The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER)
Introduction: In the setting of acute ST-segment elevation myocardial infarction (STEMI) coronary wedge pressure (CWP) emerges as a new marker for the advanced form of pre-procedural microvascular obstruction (MVO), which is…
- Trial name
- RECONSIDER (NCT03371784)
- Testing
- Hydrocortisone
- Where
- Romania
- Volunteers
- 77 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Myocardial Infarction
Adjunctive Cilostazol Versus High Maintenance-dose ClopidogrEL in Acute Myocardial Infarction (AMI) Patients According to CYP2C19 Polymorphism
Percutaneous coronary intervention (PCI) with stent implantation is the preferred reperfusion strategy for treatment of acute myocardial infarction (AMI).
- Trial name
- ACCELAMI2C19 (NCT00915733)
- Testing
- cilostazol, clopidogrel (Plavix), CYP2C19
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeongsang National University Hospital
Left Ventricular Dysfunction
Bone Marrow Derived Mononuclear Cells For Myocardial Regeneration
Evaluative pilot study for safety and feasibility with administration of autologous bone bone marrow derived mononuclear cells by endoventricular catheter into the normal border zone fo the ischemic lesion.
- Trial name
- NCT00938847
- Testing
- PCI
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Asklepios proresearch
Myocardial Infarction
STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction
This study aims at evaluating, in a proof of concept approach, the outcome of patients presenting with acute ST-elevation myocardial infarction within 3 hours of symptom onset in either a pre-hospital setting or community…
- Trial name
- NCT00623623
- Testing
- primary PCI, enoxaparin, catheterisation
- Where
- 201 sites in Austria, Belgium and 14 more
- Volunteers
- 1,899 people
- Sponsor
- Boehringer Ingelheim
Acute ST-segment Elevation Myocardial Infarction
Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention
OBJECTIVE: To determine whether a therapeutic strategy involving low-dose intracoronary fibrinolytic therapy with reteplase infused after coronary reperfusion will reduce the myocardial infarction size.
- Trial name
- RECOVERII (NCT04571580)
- Testing
- Normal Saline, Reteplase Injection 9mg, Reteplase Injection 18mg
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Ge Junbo
Heart Failure, Acute Myocardial Infarction (AMI)
Efficacy and Safety of Early Initiation of Vericiguat in Heart Failure After Acute Myocardial Infarction
Heart failure (HF) is a severe cardiovascular disease with extremely high morbidity and mortality rates worldwide, and ischemic cardiomyopathy is an important cause of heart failure.
- Conditions
- Heart Failure, Acute Myocardial Infarction (AMI), Acute Heart Failure (AHF)
- Trial name
- VIC-MI (NCT06812546)
- Testing
- Vericiguat
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Dongying Zhang
Myocardial Infarction
Coronary Anatomy Study and Times Since the Onset of Acute Myocardial Infarction Symptoms in Women Until the Opening of the Artery (TAPAC Study)
TAPAC study is an an investigator-driven, observational, prospective,cohort aimed at evaluating differences between men and women in patients undergoing primary angioplasty : hospital medical care, successful markers myocardial…
- Trial name
- TAPAC (NCT03152240)
- Testing
- Non intervention
- Where
- Spain
- Volunteers
- 800 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
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