Clinical trials: Acute Diarrhea
Diarrhea
Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea
Multicenter, open-label, controlled, randomized clinical study to evaluate the efficacy and safety of Racecadotril in infants, children and adolescents with acute diarrhea
- Trial name
- NCT03463512
- Testing
- Racecadotril plus ORS, ORS
- Where
- Russia
- Volunteers
- 124 people
- Sponsor
- Abbott
Acute Leukemias of Ambiguous Lineage, Bacterial Infection
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
This randomized phase III trial studies how well levofloxacin works in preventing infection in young patients with acute leukemia receiving chemotherapy or undergoing stem cell transplant.
- Conditions
- Acute Leukemias of Ambiguous Lineage, Bacterial Infection, Diarrhea, Fungal Infection
- Trial name
- NCT01371656
- Testing
- levofloxacin
- Where
- 84 sites in United States, Canada
- Volunteers
- 624 people
- Sponsor
- Children's Oncology Group
Diarrhea, Cholera
Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea
Diarrhea remains a leading killer of children in need of better treatments.
- Trial name
- ORS (NCT05814042)
- Testing
- Current standard control ORS (oral rehydration solution)
- Where
- Bangladesh
- Volunteers
- 396 people
- Sponsor
- University of Florida
Diarrhea, Respiratory Infection
Micronutrient Sprinkles in a Daycare Center
Diarrheal diseases are a major cause of morbidity and mortality globally in children less than 5 years of age. Prolonged diarrhea, recurrent infections and growth failure in developing countries are usually a consequence of…
- Trial name
- NCT00967551
- Testing
- Micronutrient Sprinkles with zinc, Micronutrient sprinkles without zinc
- Where
- Brazil
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Emory University
Traveler's Diarrhea
Rifamycin SV-MMX® Tablets Versus Ciprofloxacin Capsules in Acute Traveller's Diarrhoea
The purpose of this study is to prove the non-inferiority of Rifamycin SV-MMX® versus Ciprofloxacin for the treatment of adults with traveller's diarrhoea.
- Trial name
- ERASE (NCT01208922)
- Testing
- Rifamycin SV-MMX®, Ciprofloxacin
- Where
- 19 sites in Ecuador, Guatemala and 1 more
- Volunteers
- 835 people
- Sponsor
- Dr. Falk Pharma GmbH
Acute Gastroenteritis
Lactose-free Milk in Infants With Acute Diarrhea in a Developing Country
The purpose of this study is to determine whether lactose-free milk will shorten the diarrhea duration and decrease its severity in formula-fed infants presenting to the Emergency Department (ED) or pediatric clinics with acute…
- Trial name
- NCT02246010
- Testing
- Lactose- free milk
- Where
- Lebanon
- Volunteers
- 6 people
- Sponsor
- American University of Beirut Medical Center
Acute Diarrhoea
Efficacy of Diosmectite (Smecta®) in the Symptomatic Treatment of Acute Diarrhoea in Adults
The purpose of the study is to demonstrate that diosmectite efficacy is superior to placebo regarding time to recovery of an acute diarrhoea episode presumed of infectious origin in adult subjects.
- Trial name
- ADIASE (NCT02704091)
- Testing
- Smecta
- Where
- 71 sites in Algeria, Czechia and 4 more
- Volunteers
- 858 people
- Sponsor
- Ipsen
Diarrhea, Infantile
Study to Evaluate the Efficacy and Safety of Racecadotril in Children Aged 3 to 60 Months Suffering From Acute Diarrhea
This is a prospective, open-label, multicenter, single-arm study evaluating the efficacy and safety of Racecadotril the treatment of children aged 3 to 60 months suffering from acute diarrhea
- Trial name
- NCT03473561
- Testing
- Racecadotril plus ORS
- Where
- 2 sites in Taiwan
- Volunteers
- 31 people
- Sponsor
- Abbott
Diarrhoea;Acute
Efficacy of the Administration of Colloidal Silicon Dioxide in Tablet Dosage Form in Patients With Acute Diarrhea
The purpose of the study is to demonstrate the antidiarrheal efficacy of colloidal silicon dioxide in tablet dosage form (Carbowhite) in patients with acute diarrhea.
- Trial name
- NCT03633344
- Testing
- Carbowhite
- Volunteers
- 145 people
- Sponsor
- Omnifarma Kiev LLC
Infectious Diarrhea
Film Array Gastrointestinal Panel Compared to Usual Care for ED Evaluation of Infectious Diarrhea
This research study will test a laboratory test called Film-Array Gastrointestinal (GI) Panel. This GI Panel is a test that can identify the bacteria or viruses that may cause diarrhea.
- Trial name
- NCT03809117
- Testing
- Biofire Film Array Gastrointestinal Panel
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Andrew Meltzer
Cholera
Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera
Cholera still remains a global public health concern affecting both children and adults, and patients can succumb in quick time if remain untreated.
- Trial name
- NCT06193408
- Testing
- VR-AD-1005
- Where
- Bangladesh
- Volunteers
- 150 people
- Sponsor
- Hunazine Biotech S.L.
Diarrhea
Efficacy of Lactobacillus GG With Diosmectite in Treatment Children With Acute Gastroenteritis
Treatment diarrhea with Lactobacillus GG or smectite has proven efficacy. A randomized, double blind, placebo-control trial was performed to assess the effectiveness of both LGG and smectite in management of children with acute…
- Trial name
- NCT01657032
- Testing
- Smectite, Lactobacillus GG
- Where
- Poland
- Volunteers
- 88 people
- Sponsor
- Medical University of Warsaw
Gastroenteritis, Gastritis
BEKINDA (Ondansetron 24 mg Bimodal Release Tablets) for Vomiting Due to Presumed Acute Gastroenteritis or Gastritis
Randomized, Placebo-Controlled, Phase 3 Trial of RHB-102 (BEKINDA) (Ondansetron 24 mg Bimodal Release Tablets) for Acute Gastroenteritis.
- Trial name
- GUARD (NCT02246439)
- Testing
- RHB-102
- Where
- 26 sites in United States
- Volunteers
- 330 people
- Sponsor
- RedHill Biopharma Limited
Diarrhea, Gastroenteritis
Oral Zinc for the Treatment of Acute Diarrhea in US Children
Diarrheal diseases are the third leading cause of mortality in the world, with nearly 2 million deaths annually among children under age 5 years.
- Trial name
- NCT01198587
- Testing
- Zinc Sulfate
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Boston Children's Hospital
Diarrhea
Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis
It is generally recommended that oral rehydration should be used as first-line therapy to treat or prevent dehydration in children with acute gastroenteritis (AGE).
- Trial name
- NCT01467570
- Testing
- oral rehydration solution Hipp ORS Apple 200, ESPGHAN ORS
- Where
- Poland
- Volunteers
- 147 people
- Sponsor
- Medical University of Warsaw
Diarrhea, Gastrointestinal Complications
Sulfasalazine in Preventing Acute Diarrhea in Patients With Cancer Who Are Undergoing Pelvic Radiation Therapy
RATIONALE: Sulfasalazine may relieve diarrhea in patients with cancer who are undergoing pelvic radiation therapy. PURPOSE: This randomized phase III trial is studying sulfasalazine to see how well it works in preventing acute…
- Conditions
- Diarrhea, Gastrointestinal Complications, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01198145
- Testing
- sulfasalazine
- Where
- 257 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alliance for Clinical Trials in Oncology