Clinical trials: Acute Diarrhea
Diarrhea
Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea
Multicenter, open-label, controlled, randomized clinical study to evaluate the efficacy and safety of Racecadotril in infants, children and adolescents with acute diarrhea
- Trial name
- NCT03463512
- Testing
- Racecadotril plus ORS, ORS
- Where
- Russia
- Volunteers
- 124 people
- Sponsor
- Abbott
Diarrhea
Safety, Efficacy and Cost-effectiveness of Racecadotril in Children With Acute Diarrhea in Mexico
Rationale: Acute diarrhea (AD) is still a significant morbidity-mortality problem worldwide. Although oral rehydration therapy is the cornerstone, its anti-diarrheal effect is a controversial subject.
- Trial name
- Raceca-Mex (NCT01153854)
- Testing
- Racecadotril
- Where
- Mexico
- Volunteers
- 454 people
- Sponsor
- National Institute of Pediatrics, Mexico
Travelers' Diarrhea
Single Daily Dose Rifaximin for the Treatment of Travelers' Diarrhea
The study will compare durations of diarrhea among subjects who report to clinic for treatment and who receive either: 1. standard rifaximin therapy at a dose of 200 mg three times a day for 3 days, OR 2.
- Trial name
- Rifaximin 600 (NCT00875875)
- Testing
- Rifaximin
- Where
- Mexico
- Sponsor
- The University of Texas Health Science Center, Houston
Acute Diarrhea, Boswellia Serrata
Boswellia Serrata Extract in Acute Diarrhea
Acute diarrhea is a frequent problem worldwide, mostly due to gastrointestinal infections or food poisoning. Boswellia serrata could be active in the treatment of acute diarrhea due to its an-ti-inflammatory, antispasmodic and…
- Trial name
- NCT05345028
- Testing
- lecithin-based delivery form of Boswellia serrata
- Where
- Italy
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Gastrointestinal Infection
Telemedicine and Face-to-face Consultations Diagnostic Accuracy Comparison in Gastrointestinal Infection Patients
Acute gastroenterocolitis (GECA) in healthy adults is a frequent cause of looking for medical care in emergency care units and most cases are aimed at etiology viral infection or food toxin, being generally self-limited with good…
- Trial name
- NCT04803435
- Testing
- Telemedicine Consultation, Face-to-face Consultation
- Volunteers
- 100 people
- Sponsor
- Hospital Israelita Albert Einstein
Hypernatremia, Acute Watery Diarrhea
Hypernatremia Fluid Therapy in Childhood Diarrhoea
Hypernatremic dehydration is a life-threatening condition, particularly in children under two years of age, with mortality rates reaching up to as high as 19%.
- Trial name
- HOPE (NCT07884747)
- Testing
- Oral rehydration solution (ORS)
- Where
- Bangladesh
- Volunteers
- 268 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Acute Watery Diarrhea
Anti-Secretory Drug in Treatment of Acute Watery Diarrhea
In conclusion, racecadotril is an anti-secretory drug that exerts its antidiarrheal effect by inhibiting intestinal enkephalinase. It is effective in reducing the volume and frequency of stool output.
- Trial name
- NCT05216822
- Testing
- Racecadotril
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acute Watery Diarrhea
Comparison of WHO Treatment of Acute Watery Diarrhea With or Without Probiotic (Bacillus Clausii) in Children
This study aimed to compare WHO treatment of acute watery diarrhea with or without probiotic (bacillus clausii) in term of mean duration of diarrhea in children
- Trial name
- NCT06887374
- Testing
- Probiotic Bacillus Clausii
- Where
- Pakistan
- Volunteers
- 184 people
- Sponsor
- Muhammad Aamir Latif
Acute Gastroenteritis, Acute Diarrhea
Evaluation of Serum Interleukin 6 and 8 in Children With Acute Gastroenteritis
Cytokines, such as IL-6 and IL-8 can be used as markers of acute infections, including acute gastroenteritis. This study aims to evaluate serum levels of interleukins 6 and 8 in children with acute gastroenteritis.
- Trial name
- NCT05213325
- Testing
- Evaluation of serum levels of IL-6 and IL-8
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Diarrhoea
Immunological and Clinical Responses to Zinc in Children With Diarrhoea
Zinc deficiency has been found to be widespread among children in developing countries.Clinical and field studies have consistently observed an association between zinc deficiency and higher rates of infectious diseases…
- Trial name
- NCT00408356
- Testing
- Zinc
- Where
- Bangladesh
- Volunteers
- 338 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Acute Diarrhea, Acute Gastroenteritis
Use of Probiotic Yogurt in the Treatment of Acute Diarrhea in Children
The purpose of this study is to determine the effect of probiotic yogurt in acute watery diarrhea in children. The investigators will compare the effect of two different probiotics products.
- Trial name
- NCT01564290
- Testing
- Probiotic yogurt
- Where
- Bolivia
- Volunteers
- 54 people
- Sponsor
- Centro Pediatrico Albina de Patino
Malaria, Diarrhea
Clinical Evaluation of the Use of an mHealth Intervention on Quality of Care
Under the World Health Organization's (WHO) integrated community case management (iCCM) Rapid Access Expansion Program (RAcE), World Vision Niger and Canada supported the Niger Ministry of Public Health to implement iCCM in four…
- Conditions
- Malaria, Diarrhea, Acute Respiratory Infection
- Trial name
- NCT03874143
- Testing
- mHealth Intervention for Quality of Care
- Volunteers
- 520 people
- Sponsor
- World Vision Canada
Diarrhea
Impact of the Nutritional Product PTM202 on Acute and Long-Term Recovery From Childhood Diarrheal Disease
This trial will assess the impact of the nutritional product PTM202 on childhood diarrhea in Guatemalan children. The product is based on cow-milk colostrum and egg.
- Trial name
- NCT02385773
- Testing
- PTM202, Enfamil Puramino
- Where
- 2 sites in Guatemala
- Volunteers
- 321 people
- Sponsor
- University of Colorado, Denver
Acute Leukemias of Ambiguous Lineage, Bacterial Infection
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantation
This randomized phase III trial studies how well levofloxacin works in preventing infection in young patients with acute leukemia receiving chemotherapy or undergoing stem cell transplant.
- Conditions
- Acute Leukemias of Ambiguous Lineage, Bacterial Infection, Diarrhea, Fungal Infection
- Trial name
- NCT01371656
- Testing
- levofloxacin
- Where
- 84 sites in United States, Canada
- Volunteers
- 624 people
- Sponsor
- Children's Oncology Group
Acute Infectious Diarrhoea in Children
Evaluating the LGG of on Acute Infectious Diarrhea in Children
Acute diarrhea due to infectious causes is a major source of morbidity in the pediatric population. Although it is generally self-limiting, acute diarrhea may lead to severe dehydration, hospitalization, and, rarely, death…
- Trial name
- PROBAGE 2 (NCT07342101)
- Testing
- LGG, Standart of care
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 480 people
- Sponsor
- Eskisehir Osmangazi University
Acute Gastroenteritis, Diarrhea
Surveillance Study of Acute Gastroenteritis in Hospitalized Children
Acute gastroenteritis is a common cause of hospital admission and health office visits and have a huge burden on the economy of developing countries.
- Conditions
- Acute Gastroenteritis, Diarrhea, Dehydration
- Trial name
- SAGE (NCT02245139)
- Volunteers
- 198 people
- Sponsor
- Shaikh Ragheb Harb Hospital
Diarrhoea;Acute, Diarrhea Travelers
Single Dose Antibiotic Treatment of Acute Watery Diarrhea, Rifaximin Versus Azithromycin, With Loperamide Adjunct
The purpose of this study is to compare a single dose of rifaximin with loperamide to the current standard approach of single dose azithromycin with loperamide for the treatment of acute watery traveler's diarrhea (TD).
- Trial name
- TrEAT_TD2 (NCT05677282)
- Testing
- Rifaximin 550 MG, Azithromycin 500 MG, Loperamide
- Where
- 4 sites in Djibouti, Honduras and 2 more
- Volunteers
- 150 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Dehydration, Acute Gastroenteritis
Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)
To compare length of stay (LOS) of pediatric patients in a pediatric emergency room presenting with Gastroenteritis treated with IV rehydration versus oral Speedlyte rehydration.
- Trial name
- NCT03562702
- Testing
- Standard IV Rehydration Therapy, Oral Rehydration Therapy (ORT)
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Acute Bacterial Gastroenteritis
Safety and Efficacy of Prulifloxacin vs Placebo in Treatment of Acute Gastroenteritis in Adult Travelers
The objective of this pivotal Phase III study is to investigate the safety and efficacy of prulifloxacin versus placebo in the treatment of patients with acute bacterial gastroenteritis (traveler's diarrhea.
- Trial name
- NCT00448422
- Testing
- prulifloxacin
- Where
- India
- Volunteers
- 268 people
- Sponsor
- Optimer Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Diarrhea, Cholera
Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea
Diarrhea remains a leading killer of children in need of better treatments.
- Trial name
- ORS (NCT05814042)
- Testing
- Current standard control ORS (oral rehydration solution)
- Where
- Bangladesh
- Volunteers
- 396 people
- Sponsor
- University of Florida