Clinical trials: ACL Reconstruction, active
Knee, ACL
Restoration of Knee Extension After ACL Reconstruction
The purpose of this study is to determine whether the addition of a home-based high-intensity knee extension stretching device (Ermi Knee Extensionater) to standard postoperative physical therapy improves recovery of full knee…
- Trial name
- NCT07685561
- Testing
- Standard Physical Therapy, Ermi Knee Extensionater
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Alabama at Birmingham
Anterior Cruciate Ligament Reconstruction Rehabilitation, Blood Flow Restriction (BFR) Training Effects
Effect of Blood Flow Restriction Rraining on Rehabilitation After Anterior Cruciate Ligament Reconstruction
Importance: Following anterior cruciate ligament reconstruction (ACLR), patients often experience quadriceps muscle weakness and atrophy, frequently leading to long-term complications.
- Trial name
- NCT07311031
- Testing
- Blood flow restriction training, Standard ACL rehabilitation
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital MAZ
Anterior Cruciate Ligament Injuries
A Study Of Focused Shockwave For Anterior Knee Pain Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to investigate whether Focused Shockwave (FSW) therapy reduces anterior knee pain following anterior cruciate ligament reconstruction (ACL-R) with bone-patellar tendon-bone (BTB) or quadriceps tendon…
- Trial name
- NCT07580157
- Testing
- Focused Shockwave
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Anterior Cruciate Ligament (ACL) Rupture, Anterior Cruciate Ligament (ACL) Reconstruction
Comparison of Video Based Phone App vs. Supervised Preoperative Exercise for ACL Reconstruction
The goal of this clinical trial is to learn if using a phone app for exercises is as effective as working with a physical therapist before anterior cruciate ligament knee surgery.
- Conditions
- Anterior Cruciate Ligament (ACL) Rupture, Anterior Cruciate Ligament (ACL) Reconstruction, Anterior Cruciate Ligament (ACL) Injury
- Trial name
- ACL-PREHAB-APP (NCT07322497)
- Testing
- Mobile App Exercise Program, Supervised Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Anterior Cruciate Ligament (ACL)
Preoperative Rehabilitation for Patient With an ACL Injury
Muscle qualities are critical for the recovery after an anterior cruciate ligament (ACL) injury. Before ACL reconstruction (ALCR), resistance training aims to maintain patient strength and volume in order to optimize recovery.
- Trial name
- K-POP (NCT07411625)
- Testing
- Resistance training, Traditional exercises
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Nantes University Hospital
Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation
Fractal vs Isochronous Cueing in Athletes After ACL Reconstruction
Anterior cruciate ligament (ACL) injuries are among the most prevalent and functionally limiting knee injuries in sports, particularly those that involve pivoting movements.
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Athlete
- Trial name
- SyncGait (NCT07243535)
- Testing
- Fractal Cueing, Isochronous Cueing
- Where
- Portugal
- Volunteers
- 36 people
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation
The Effect of Plyometric Training in Post-ACLR Surgery
The primary goal of this RCT is to evaluate the effect of adding plyometric training on standard program intervention in patients aged 18-40 years who have undergone ACLR surgery.
- Conditions
- Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament/Surgery, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- NCT07862881
- Testing
- Standard program, Plyometrics Training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament Injuries, Postoperative Pain
Multimodal Analgesia vs. Femoral Block in ACL Surgery
This study aims to compare the effects of a preemptive multimodal intravenous analgesia protocol and a femoral triangle block on early postoperative rehabilitation compliance in patients undergoing anterior cruciate ligament…
- Conditions
- Anterior Cruciate Ligament Injuries, Postoperative Pain, Pain, Postoperative
- Trial name
- MAPvsFTB (NCT06936995)
- Testing
- Preemptive Multimodal Intravenous Analgesia, Femoral Triangle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Ankara University
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Clinical and Biological Outcomes of BioBrace-Augmented ACL Reconstruction
This prospective, single-center, single-arm observational cohort study aims to evaluate the clinical, radiological, and arthroscopic outcomes and safety of primary anterior cruciate ligament (ACL) reconstruction augmented with…
- Trial name
- NCT07906860
- Testing
- BioBrace® Reinforced BioInductive Implant
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries
Correlation Between Psychological Readiness, Knee Function, and Isokinetic Performance After Anterior Cruciate Ligament Reconstruction (ACLR) Using Peroneus Longus Tendon Graft (PL-ACL-2025)
This clinical trial aims to investigate the correlation between psychological readiness, knee function, and isokinetic performance after anterior cruciate ligament reconstruction (ACLR) using the Peroneus Longus tendon graft…
- Conditions
- Anterior Cruciate Ligament (ACL) Injury, Athletic Injuries, Knee Injuries
- Trial name
- PL-ACLR (NCT07201597)
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Anterior Cruciate Ligament (Acl) Reconstruction
The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction surgery is a common procedure performed by orthopedic surgeons. Postoperatively, patients often experience pain, muscle tension, and concerns about their ability to return to…
- Trial name
- NCT06382324
- Testing
- mindfulness practice of body scan, listening to light music
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament Reconstruction
Tourniquet vs. Dual-flow Arthroscopy Sheath in Anterior Cruciate Ligament (ACL) Reconstruction
This is a prospective randomized study comparing tourniquet use versus a dual-flow arthroscopy sheath in Anterior Cruciate Ligament (ACL) reconstruction surgery.
- Trial name
- RELICA (NCT06819696)
- Testing
- ACL reconstruction with a dual-flow arthroscopy sheath, ACL reconstruction with a thigh tourniquet
- Where
- 3 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Bone Graft; Complications, ACL Injuries
Radiographic Findings and Clinical Outcomes After Bone Grafting Patellar Defect in ACL Reconstruction
All patients will be randomly assigned using a computer randomization algorithm to one of two matched cohort groups. Patients will not be advised which group they belong to until after the completion of the study.
- Trial name
- BTB BackFill (NCT06975306)
- Testing
- autologous bone grafts, Demineralized bone matrix (DBM)
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Arizona
Anterior Cruciate Ligament (ACL) Tear
Effects of a Preoperative Cognitive-Behavioral Intervention on Kinesiophobia and Function in Anterior Cruciate Ligament Reconstruction
This study aims to systematically elucidate the integrative effects of psychological rehabilitation on the "brain-psychology-motor" triad in patients with anterior cruciate ligament (ACL) rupture.
- Trial name
- NCT07423767
- Testing
- Cognitive-Behavioral Intervention, Control group
- Where
- 2 sites in China
- Volunteers
- 44 people
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Rupture
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
The Investigators are studying the effect of an ACL reconstruction on return to play by capturing outcome measures and biomechanics information.
- Trial name
- NCT06294314
- Testing
- Fertilized ACL
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Marshall University
ACL Repair
The Effect of Pre-Operative Cryoneurolysis on Post-Operative Narcotic Consumption in Patients Undergoing Autograft ACL Reconstruction
The purpose of the research is to investigate the effect of preoperative Cryoneurolysis of the knee on postoperative pain management in patients undergoing autograft anterior cruciate ligament (ACL) reconstruction (a surgical…
- Trial name
- NCT06603051
- Testing
- Cryoneurolysis
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Virtua Health, Inc.
ACL
LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study
The Anterior Cruciate Ligament (ACL) is a major stabiliser of the knee. ACL rupture is being increasingly identified in children and skeletally immature patients.
- Trial name
- LivD_ACLR (NCT05395767)
- Testing
- Endoscopic Anterior Cruciate Ligament reconstruction using living donor hamstring allograft from a parent donor
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maidstone & Tunbridge Wells NHS Trust
ACL Reconstruction
Application of Multiple Vertical Jump Tests in Return-to-Play Assessment for Anterior Cruciate Ligament Reconstruction Athletes
Anterior cruciate ligament (ACL) injury is a common sports-related injury, particularly in sports that require extensive jumping and cutting movements.
- Trial name
- RTP-VJ (NCT07297511)
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University