Clinical trials: sponsored by Icahn School of Medicine at Mount Sinai
Autism Spectrum Disorder
A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder
The proposed project will pilot the use of IGF-1 as a novel treatment for core symptoms of autism. We will use a double-blind, placebo-controlled crossover trial design in five children with autism to evaluate the impact of IGF-1…
- Trial name
- NCT01970345
- Testing
- IGF-1
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Long COVID, Chronic Fatigue Syndrome
Vagus Nerve Stimulation as Treatment for Long Covid
Many patients do not recover following Covid infection. The resulting illness is called Long Covid. Because there is no agreed upon treatment for this ailment, the research team has decided to do an open label pilot study using…
- Trial name
- NCT05608629
- Testing
- Transcutaneous Non-Invasive Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Type 2 Diabetes
TEEN HEED: An Adolescent Diabetes Prevention Intervention Incorporating Novel Mobile Health Technologies
The number of youth with type 2 diabetes in the U.S. is projected to increase by a staggering 49 percent by 2050, with higher rates among minority youth.
- Trial name
- NCT05560386
- Testing
- Text messaging, Virtual workshop
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Genetic Diseases, Inborn, Genetic Predisposition to Disease
NYCKidSeq: Incorporating Genomics Into Clinical Care of Diverse NYC Children
The NYCKidSeq program will significantly advance the implementation of genomic medicine, particularly for children, young adults and their families in Harlem and the Bronx.
- Trial name
- NCT03738098
- Testing
- Standard of Care, GUÍA
- Where
- 2 sites in United States
- Volunteers
- 650 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Preterm Birth
NICU-HEALTH (Hospital Exposures and Long-Term Health)
The purpose of this study is to evaluate the impact of environmental exposures during the NICU hospitalization on preterm infant development. The research team is interested in both chemical and non-chemical exposures.
- Trial name
- NCT01963065
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
22q13 Deletion Syndrome, Phelan-McDermid Syndrome
Clinical Trial in 22q13 Deletion Syndrome(Phelan-McDermid Syndrome)
The purpose of this study is to pilot the use of Insulin-Like Growth Factor-1 (IGF-1) treatment in 22q13 Deletion Syndrome (Phelan-McDermid Syndrome) caused by SHANK3 gene deficiency in order to evaluate safety, tolerability, and…
- Trial name
- NCT01525901
- Testing
- Insulin-Like Growth Factor-1 (IGF-1), Normal saline
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
First Episode Psychosis (FEP), At Risk Mental State (ARMS)
Reducing the Duration of Untreated Psychosis in the United States
The goal of this project is to investigate whether a systematic screening approach for individuals with first episode psychosis (FEP) can substantially reduce Duration of Untreated Psychosis (DUP).
- Trial name
- NCT03369730
- Where
- 3 sites in United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
COPD, Diabetes
Healthy Mediation Adherence To Transform and Effectively Relieve Symptoms
The goal of the parent R01 study has been to determine how beliefs about chronic illness and their treatments affect SMB in the context of chronic obstructive pulmonary disease (COPD) with comorbid hypertension (HTN) and or…
- Conditions
- COPD, Diabetes, Hypertension
- Trial name
- NCT04656093
- Testing
- Supportive counseling, Education on SMB, Psychoeducation on ATs for maladaptive beliefs (if applicable)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Inflammatory Bowel Disease
Precision IFX: Using a Dashboard to Individualize Infliximab Dosage
The introduction of infliximab (IFX) and other monoclonal antibodies (MAbs) targeting tumor necrosis factor (TNF) was a major advancement in the management of inflammatory bowel disease (IBD).
- Trial name
- NCT02624037
- Testing
- Individualized Dosage Precision IFX Dashboard
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Attention Deficit Hyperactivity Disorder, ADHD
Imaging Stimulant and Non Stimulant Treatments for ADHD: A Network Based Approach
The growing number of medications used to treat attention-deficit/hyperactivity disorder (ADHD) raises important questions about whether different medications have similar or different therapeutic mechanisms of action.
- Trial name
- NCT01678209
- Testing
- fMRI scans, Atomoxetine arm, Methylphenidate arm
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Erythropoietic Protoporphyria, EPP
Erythropoietic Protoporphyrias: Studies of the Natural History, Genotype-Phenotype Correlations, and Psychosocial Impact
The initial objective of this protocol is to assemble a well-documented group of patients with confirmed diagnoses of the erythropoietic protoporphyrias, including autosomal recessive Erythropoietic Protoporphyria (EPP) and…
- Conditions
- Erythropoietic Protoporphyria, EPP, X-Linked Protoporphyria, XLP
- Trial name
- NCT01688895
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pre-Diabetes
Community-based Adolescent Diabetes Prevention Program
The number of youth with type 2 diabetes is predicted to quadruple by 2050, with a disproportionate increase among minority youth.
- Trial name
- NCT02458131
- Testing
- TEEN HEED
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Diabetes, Obesity
Project Powerfood: Promoting Food Security, Equity, and Health
Project Powerfood is a pilot program aimed at addressing food insecurity and food access in primary care through the implementation of a food prescription program in collaboration with a number of community partners.
- Trial name
- NCT03246997
- Testing
- Autumn Group, Spring Group
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ulcerative Colitis, Inflammatory Bowel Diseases
Complications and Outcomes of Pouch Excision
Procedure is offered today to most patients with chronic ulcerative colitis (CUC) or familial adenomatous polyposis (FAP) who are candidates for total proctocolectomy.
- Trial name
- NCT03952195
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Crohn's Disease
The Use of Small Bowel Ultrasound to Predict Response to Remicade Induction
Small bowel ultrasound (SBUS) is emerging as a well tolerated, non-invasive, radiation free, low cost measure to assess inflammatory bowel disease (IBD), and is being used as first-line imaging in Europe.
- Trial name
- NCT02488005
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Promoting Cardiovascular Health in Younger Age Group
Family-based Approach to Promotion of Health - FAMILIA (Project 1)
Problem: Childhood obesity has more than doubled over the past 30 years, with nearly one-third of children aged 6 to 11 years being obese.
- Trial name
- FAMILIA (NCT02343341)
- Testing
- Preschool Health Promotion Education Program
- Where
- 15 sites in United States
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Inflammatory Bowel Diseases, Ileostomy
Malnutrition Associated With Complications After Ileostomy Reversal
An ileostomy is a surgical opening established by bringing the end or a loop of the ileum to discharge directly outside the body.
- Trial name
- NCT03909542
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Health
Salud Integral Colombia
In May 2009 in Bogota, Colombia, the Si! program conducted a cluster randomized trial in 1216 children between the ages of 3 and 6 years old, and 928 parents with the aim of evaluating a five month education intervention to…
- Trial name
- NCT03119792
- Testing
- Education Intervention, Control
- Where
- Colombia
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Food Allergy
Anxiety About Casual Exposure to Food Allergens
Living with food allergy may result in anxiety and reduced quality of life. Food allergic patients and their families are often concerned about casual exposure with the offending allergen through skin contact or being near the…
- Trial name
- TOUCH (NCT03349047)
- Testing
- Behavioral intervention group, Education
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Keratoconus, Ectasia
Safety and Effectiveness of Corneal Crosslinking (CXL): Keratoconus and Post-Refractive Ectasia
This prospective, randomized study is being conducted to evaluate the safety and effectiveness of corneal cross-linking (CXL) in patients with keratoconus or post-refractive ectasia (post-LASIK or PRK) utilizing two techniques…
- Trial name
- CXL (NCT03080077)
- Testing
- Ricrolin+, Epi-Off
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Icahn School of Medicine at Mount Sinai