Specialty
Psychiatry clinical trials
Trials in depression, anxiety, schizophrenia, bipolar disorder, PTSD, ADHD and substance use.
About psychiatry research
Mental health studies include medicines, talking therapies, digital programmes and neuromodulation. Many enrol people through community and primary-care services as well as specialist clinics.
Research areas
Open trials in each area. Counts come from the latest copy of the registry.
Recently updated open trials
Studies looking for volunteers, most recently updated by their sponsors first.
Major Depressive Disorder, Bipolar I Disorder
Digital Phenotypes for Predicting Depression_Validation
This 12-month, single-site prospective observational study will prospectively monitor the recurrence of mood episodes while continuously collecting passive digital phenotypes in individuals with and without mood disorders.
- Conditions
- Major Depressive Disorder, Bipolar I Disorder, Bipolar II Disorder, Mood Disorders
- Trial name
- NCT07880015
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Depression - Major Depressive Disorder
Understanding the Neural Underpinnings of Risk-Taking Behavior in Psychiatric Disease
The purpose of this study is to understand how the orbitofrontal cortex (OFC), a region at the front of the brain, guides decisions about whether to pursue a possible reward when doing so also carries a risk of loss, and how this…
- Trial name
- NCT07896343
- Testing
- Approach-Avoidance Decision-Making Task
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Francisco
Anxiety Symptoms, Anxiety Disorders
TOUCHminds: Help-seeking in Adolescents With Anxiety
Adolescents frequently experience clinical and subclinical anxiety symptoms, yet many avoid seeking professional help. While universal interventions exist to promote help-seeking, targeted programs for adolescents with elevated…
- Trial name
- TOUCHminds (NCT07366580)
- Testing
- TOUCHminds - Web-Based Intervention
- Where
- Portugal
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Substance Use Disorders (SUDs)
Development of an Interview-Informed Timeline Follow-Back (TLFB) for Opioid Use in the Era of Fentanyl
Background: A Timeline Follow-Back (TLFB) is a tool that helps researchers track how much of a substance a person uses. Different versions of the tool are used to track the use of alcohol, cigarettes, and cannabis.
- Trial name
- NCT06995885
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Abdominal Pain/ Discomfort, Irritable Bowel Syndrome
The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain
The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.
- Trial name
- NCT06706778
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
Opioid Use, Fractures, Bone
Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
An open reduction and internal fixation is a painful procedure requiring intensive postoperative pain management. Traditionally, opioid analgesia has been the gold standard for postoperative pain control.
- Conditions
- Opioid Use, Fractures, Bone, Trauma
- Trial name
- NCT06113211
- Testing
- Narcotic pain medication, Nonnarcotic pain medications
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Henry Ford Health System
Chronic Pain, Musculoskeletal Pain
Multicomponent Exercise and Pain Science Education for Fall Prevention in Older Adults With Chronic Musculoskeletal Pain (MovePainFall)
Chronic musculoskeletal pain is common in older adults and is associated with reduced mobility, loss of function, poorer quality of life, fear of movement, fear of falling and a higher risk of falls.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Accidental Falls, Fear of Falling
- Trial name
- MovePainFall (NCT07889024)
- Testing
- MovePainFall multicomponent exercise programme, Pain science and fall-prevention education
- Where
- Portugal
- Volunteers
- 40 people
- Sponsor
- Instituto Politécnico de Bragança
Depressive Disorder, Major, Inflammation
Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab
This study is a mechanistic randomized controlled trial that investigates whether inhibition of tumor necrosis factor signaling via intravenous infusion of infliximab improves psychomotor speed and executive functioning in…
- Trial name
- NCT06136546
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Narrow the search
Conditions in psychiatry
Conditions with their own page on AzTrials, with the number of registered studies.
- Depression 4,580
- Anxiety 3,452
- Schizophrenia 2,954
- Major Depressive Disorder 1,731
- Autism Spectrum Disorder 1,343
- Bipolar Disorder 1,145
- Alcohol Use Disorder 640
- Anxiety Disorders 629
- PTSD 592
- Attention Deficit Hyperactivity Disorder 573
- Schizoaffective Disorder 547
- Mental Health 541
- Opioid Use 531
- Depressive Symptoms 529
- Autism 522
- Depressive Disorder 497
- Posttraumatic Stress Disorder 482
- ADHD 481
- Opioid Use Disorder 438
Questions about psychiatry trials
Which trials are counted as psychiatry?
Studies whose conditions, or the medical subject headings the registry adds to them, mention any of these terms: depression, depressive, anxiety, schizophrenia, bipolar, ptsd, stress disorder, adhd, autism, substance use, alcohol use, opioid use. A study can belong to more than one specialty, and the grouping is AzTrials', not the sponsor's.
Are all of these trials recruiting?
No. The lists on this page show studies open to volunteers (recruiting, not yet recruiting or enrolling by invitation), as the sponsor last reported. The full search also includes completed and stopped studies, some with posted results.
How can I refer a patient to one of these trials?
Open the trial and use the contacts and sites it lists; the For doctors view of each trial collects them with the key eligibility criteria. AzTrials does not enrol participants or take referrals.