Specialty
Oncology clinical trials
Trials of treatments, screening and supportive care for solid tumours and blood cancers.
About oncology research
Cancer studies make up the largest share of the registry. Many are early-phase studies of targeted therapies and immunotherapies; others compare established treatment combinations, test screening approaches or look at quality of life during treatment.
Research areas
Open trials in each area. Counts come from the latest copy of the registry.
Recently updated open trials
Studies looking for volunteers, most recently updated by their sponsors first.
Lung Neoplasms, Neoadjuvant Therapy
MRD-Guided Postoperative Surveillance and Adaptive Treatment for Resectable Lung Cancer
This study is a prospective single-arm clinical trial targeting patients with stage IB-IIIA non-small cell lung cancer (NSCLC) who have received neoadjuvant immunotherapy.
- Conditions
- Lung Neoplasms, Neoadjuvant Therapy, Immunotherapy, Minimal Residual Disease
- Trial name
- NCT07894458
- Testing
- Adaptive therapy of de-escalation and escalation based on MRD testing and pathological response
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Cachexia-Anorexia Syndrome, Cachexia; Cancer
A Phase II Clinical Study Evaluating the Efficacy and Safety of SXRN Injection in Patients With Cancer Cachexia
This is a multicenter, randomized, double-blind, placebo-controlled, dose-finding Phase II clinical study to evaluate the efficacy and safety of SXRN injection in adult patients with cancer-associated anorexia-cachexia.
- Trial name
- NCT07890324
- Testing
- SXRN Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Jiangsu Guiqiong Pharmaceutical Co., Ltd.
Esophageal Squamous Cell Carcinoma, Immunotherapy
Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC
To evaluate the efficacy and safety of adebrelimab with or without induction chemotherapy followed by concurrent chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma
- Conditions
- Esophageal Squamous Cell Carcinoma, Immunotherapy, Biomarkers
- Trial name
- RICE (NCT06510660)
- Testing
- adebrelimab
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Fujian Medical University Union Hospital
Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia
The goal of this clinical trial is to learn if sonrotoclax (BGB-11417) is safe and may help treat children and adolescents with acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) that has come back after treatment…
- Conditions
- Relapsed Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia, B-cell Acute Lymphoblastic Leukemia, Pediatric Cancer
- Trial name
- NCT07770698
- Testing
- sonrotoclax, Azacitidine, Inotuzumab ozogamicin
- Volunteers
- 30 people
- Sponsor
- BeOne Medicines
Intrahepatic Cholangiocarcinoma (Icc)
Intraarterial Therapies Plus Tislelizumab Plus Lenvatinib Versus Tislelizumab Plus Gemcitabine-Cisplatin in Unresectable Intrahepatic Cholangiocarcinoma
This is a phase III, multicenter, open-label, randomized controlled trial designed to evaluate the efficacy and safety of arterially directed therapy in combination with tislelizumab plus lenvatinib compared with gemcitabine and…
- Trial name
- RAINBOW (NCT07691515)
- Testing
- Gemcitabine, Cisplatin, Tislelizumab
- Where
- 21 sites in China
- Volunteers
- 140 people
- Sponsor
- Zhejiang Cancer Hospital
B-All, Acute Lymphoblastic Leukemia
Anti-CRLF2-R/TSLPR Chimeric Antigen Receptor T Cells (TSLPR-CART) in Participants With Recurrent or Refractory CRLF2-R/TSLPR-Overexpressing B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Background: B-cell acute lymphoblastic leukemia (B-ALL) is a type of blood cancer. Some people with B-ALL have a gene mutation that makes the disease hard to treat.
- Trial name
- NCT07572136
- Testing
- TSLPR-CART, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- National Cancer Institute (NCI)
Melanoma
Community Based Strategies for Early Detection of Melanoma
The purpose of this study is to pilot the use of community education and digital dermatology to increase the early detection of curable melanomas.
- Trial name
- NCT04799106
- Testing
- Community Based Strategies for Early Detection of Melanoma
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Acute Lymphoblastic Leukemia, B-All
CD22 CAR T-cells to Extend Remission Following Commercial CD19 CAR T-cells in Children, Adolescents, and Adults With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Background: Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Chimeric antigen receptor (CAR) therapy involves taking immune cells (T cells) from a person and modifying them to better target cancer cells.
- Trial name
- NCT07328503
- Testing
- CD22 CAR-transduced T cells, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Narrow the search
Conditions in oncology
Conditions with their own page on AzTrials, with the number of registered studies.
- Breast Cancer 8,950
- Prostate Cancer 4,508
- Cancer 4,042
- Colorectal Cancer 3,511
- Lung Cancer 3,124
- Non-small Cell Lung Cancer 3,105
- Multiple Myeloma 2,359
- Ovarian Cancer 2,092
- Lymphoma 2,058
- Pancreatic Cancer 1,968
- Gastric Cancer 1,822
- Hepatocellular Carcinoma 1,820
- Leukemia 1,665
- Head and Neck Cancer 1,611
- Acute Myeloid Leukemia 1,483
- Melanoma 1,467
- Cervical Cancer 1,312
- Neoplasms 1,125
- Bladder Cancer 1,119
- Solid Tumor 1,066
- Esophageal Cancer 1,056
- Rectal Cancer 985
- Breast Neoplasms 972
- Metastatic Breast Cancer 912
- Glioblastoma 905
- Endometrial Cancer 866
- Advanced Solid Tumors 840
- Colon Cancer 830
- Solid Tumors 787
- Sarcoma 777
- Advanced Solid Tumor 775
- Unspecified Adult Solid Tumor, Protocol Specific 758
- Chronic Lymphocytic Leukemia 750
- Carcinoma, Non-Small-Cell Lung 677
- Colorectal Neoplasms 666
- Acute Lymphoblastic Leukemia 661
Questions about oncology trials
Which trials are counted as oncology?
Studies whose conditions, or the medical subject headings the registry adds to them, mention any of these terms: cancer, tumor, neoplasm, lymphoma, leukemia, myeloma, melanoma, carcinoma, sarcoma, glioma, glioblastoma. A study can belong to more than one specialty, and the grouping is AzTrials', not the sponsor's.
Are all of these trials recruiting?
No. The lists on this page show studies open to volunteers (recruiting, not yet recruiting or enrolling by invitation), as the sponsor last reported. The full search also includes completed and stopped studies, some with posted results.
How can I refer a patient to one of these trials?
Open the trial and use the contacts and sites it lists; the For doctors view of each trial collects them with the key eligibility criteria. AzTrials does not enrol participants or take referrals.