Clinical trials: completed, sponsored by University of Michigan
Breast Cancer, Colorectal Cancer
Michigan Genetic Hereditary Testing (MiGHT)
The primary purpose of this study is to compare three interventions, two experimental and one standard of care (usual care), to see if the experimental interventions will increase the likelihood of a participant obtaining…
- Conditions
- Breast Cancer, Colorectal Cancer, Ovarian Cancer, Prostate Cancer
- Trial name
- MiGHT (NCT05162846)
- Testing
- Publicly available genetic testing resources, Virtual genetics navigator, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- University of Michigan Rogel Cancer Center
Mild Cognitive Impairment, Alzheimer Disease
Behavioral Change Following Alzheimer's Disease (AD) Biomarker Disclosure
The proposed project will assess long-term changes to health/lifestyle, advanced planning, and research engagement that Black and White patients with Amnestic Mild Cognitive Impairment (aMCI) make following disclosure of positron…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Amnestic Mild Cognitive Disorder
- Trial name
- SHARED III (NCT05584241)
- Testing
- Diagnostic Disclosure Protocol, Biomarker Disclosure Protocol
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Michigan
Scleroderma, Gastroparesis
TENS in Scleroderma
The goal of this pilot study is to assess the acceptability of the transcutaneous electrical acustimulation (TEA) device in treating Scleroderma-related gastroparesis.
- Conditions
- Scleroderma, Gastroparesis, Systemic Sclerosis (SSc)
- Trial name
- NCT06646913
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Physical Inactivity
Tele-video to Improve Daily Activity
This pilot study will test the feasibility of pairing a social network-based approach with a 6-week Occupational Therapist (OT)-led intervention administered remotely (via Zoom) to increase physical function and activity among…
- Trial name
- T-VIDA (NCT06007664)
- Testing
- Tele-Video to Improve Daily Activity
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sebaceous Hyperplasia
Investigating the Effect of Topical Imiquimod on Sebaceous Hyperplasia
This study is being completed to determine if 8 weeks of treatment with imiquimod can shrink sebaceous hyperplasia.
- Trial name
- NCT06840470
- Testing
- Imiquimod 5% Topical Cream
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Oropharynx Cancer
Individualized Adaptive De-escalated Radiotherapy for HPV-related Oropharynx Cancer
This prospective study aims to utilize pre- and mid-treatment PET-CT to guide de-escalation of radiation therapy in HPV-related squamous cell carcinoma of the oropharynx.
- Trial name
- NCT03416153
- Testing
- Carboplatin, Radiation Therapy, Paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 91 people
- Sponsor
- University of Michigan Rogel Cancer Center
Diabetes Mellitus, Type 2
Michigan Men's Diabetes Project 2
The Michigan Men's Diabetes Project 2 (MenD 2) is an 18-month pilot randomized clinical trial. We are looking to recruit 60 Black men with type 2 diabetes (need to have diagnosis for at least 6 months) that are over the age of…
- Trial name
- MenD 2 (NCT05370781)
- Testing
- Peer Led Diabetes Self-Management Support, Diabetes Self-Management Education
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Cirrhosis, Liver, Portal Hypertension
LiveSMART Trial to Prevent Falls in Patients With Cirrhosis
This multicenter trial is being conducted to determine if sequential lactulose and Tele (virtual) Tai-Chi reduces the rate of injurious fall, non-injurious falls, incident overt Hepatic Encephalopathy (HE), and death or liver…
- Trial name
- NCT05794555
- Testing
- Enhanced Usual Care, Lactulose, Investigator recommended exercise
- Where
- 3 sites in United States
- Volunteers
- 233 people
- Sponsor
- University of Michigan
Quality of Life, Catheter-Associated Urinary Tract Infection
Evaluation of Quality-of-Life Improvements Using UroShield Device
The goal of this pilot study is to test key elements of the full study that will follow, including recruitment and retention strategies, intervention delivery, laboratory testing, data collection methods, and adherence to study…
- Trial name
- NCT06319352
- Testing
- Active UroShield
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anxiety
Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors
Demonstrate the feasibility of conducting an eight-week, (45 min/week), theory driven, virtually-delivered, tailored music-based relaxation (TiMBRe) intervention to decrease anxiety in adolescent and young adult (AYA) cancer…
- Trial name
- NCT05911269
- Testing
- TiMBRe, Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Smart-Quality Physical Education
Sustaining Quality Physical Education for Healthy Kids
The purpose of the study was to examine the effects of the technology-enhanced quality physical education (Smart-QPE) lessons on physical activity, cardiorespiratory fitness, social emotional learning (SEL) skills, and mental…
- Trial name
- NCT07227935
- Testing
- Smart-QPE
- Where
- United States
- Volunteers
- 1,165 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Relapsed Chronic Lymphocytic Leukemia
A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL
Metformin is an antidiabetic drug which is an inexpensive and generally well tolerated medication. More recently metformin has been shown to act against carcinomas by two mechanisms: 1) an indirect, insulin-dependent mechanism…
- Trial name
- NCT01750567
- Testing
- Metformin
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Michigan Rogel Cancer Center
Gastroparesis With Diabetes Mellitus
Transcutaneous Electrical Acustimulation (TEA) for Gastroparesis
The device being studied, the Transcutaneous Electrical Accustimulator (TEA), will deliver weak electrical current at two specific points, one at the leg and the other at the arm at settings known to improve symptoms involving…
- Trial name
- NCT05362578
- Testing
- transcutaneous electrical accustimulation at treatment point.
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Michigan
Human Gastrointestinal Physiology Data
Pharmacokinetic Study of Single-Dose Modified Release Glipizide in Healthy Volunteers
In vivo drug dissolution in the gastrointestinal (GI) tract is largely unmeasured. The purpose of this clinical study is to evaluate the in vivo drug dissolution and systemic absorption of modified release formulations of the BCS…
- Trial name
- NCT05159427
- Testing
- Glucotrol XL 5Mg Extended-Release Tablet, Glipizide ER 5 MG 24 HR Extended Release Oral Tablet, Rifaximin 200Mg Tab
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression
You Are What You Eat: Food as a Risk Factor and a Treatment for Depression
This study experimentally investigates 1) whether ultra processed food (UPF) intake contributes to depression by increasing low mood and poor sleep due to blood glucose fluctuations (which then increases the desire to consume…
- Trial name
- NCT06242665
- Testing
- Low UPF Meals (Study Provided), Low UPF Nutritional Guidance, Low UPF Snacks (Study Provided)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Michigan
Stuttering, Stuttering, Childhood
Speech Processing in Stuttering
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech.
- Conditions
- Stuttering, Stuttering, Childhood, Stuttering, Adult
- Trial name
- NCT04929184
- Testing
- Speech and non-speech tasks
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study
The objective of this study is to test the effects of caffeine on neurocognitive and clinical recovery after major surgery. Specifically, this trial tests the primary hypothesis that caffeine will reduce the incidence of…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Mild Cognitive Impairment
- Trial name
- NCT05574400
- Testing
- Dextrose Water, Caffeine citrate
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Michigan
Suicide, Suicide, Attempted
Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care
This study is being completed to examine different combinations of technology-augmented strategies to identify an effective Adaptive intervention (AI) addressing post-discharge suicide risk with high implementation potential.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
- Trial name
- NCT05282225
- Testing
- MI- Safety Plan, Texts messages, Monitoring
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced
Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients
A multicenter, randomized, adaptive allocation clinical trial to determine if increasing durations of induced hypothermia are associated with an increasing rate of good neurological outcomes and to identify the optimal duration…
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
- Trial name
- ICECAP (NCT04217551)
- Testing
- Therapeutic Hypothermia
- Where
- 76 sites in United States
- Volunteers
- 1,158 people
- Sponsor
- University of Michigan
Endodontically Treated Teeth
Alternative EndoCrowns Designs for Chairside CAD/CAM
This investigation will be a longitudinal clinical trial to study the association of preparation design on the internal and marginal adaptation of the resulting restorations and the long-term clinical performance of chairside…
- Trial name
- NCT04604314
- Testing
- CEREC Tessera
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Michigan
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