Clinical trials: sponsored by Icahn School of Medicine at Mount Sinai
Growth in Premature Infants
Early Protein Supplementation of Human Milk in Extremely Low Birth Weight Infants
We hypothesize that premature infants who receive their mothers' expressed breast milk supplemented with liquid protein early in their hospitalization will have a growth velocity in the first 28 days of life that is 20% greater…
- Trial name
- NCT01991613
- Testing
- liquid protein supplement
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Advanced Cancer, Metastatic Cancer
Emergency Department-Based Palliative Care for Advanced Cancer Patients
The purpose of this study is to: 1) identify the palliative care needs of Emergency Department patients with advanced cancer, and determine if these needs can be rapidly assessed in the ED; 2) determine whether early palliative…
- Trial name
- NCT01358110
- Testing
- Early palliative care consultation, Care as usual
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV Infections, Hepatitis C
Effects of HIV and Hepatitis C Virus on the Brain
This study will determine the effects that HIV and hepatitis C virus have on thinking abilities and whether the viruses affect brain chemistry.
- Trial name
- NCT00494936
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Metabolic Syndrome
Effect of a Low Advanced Glycation End Products (AGE) Diet in the Metabolic Syndrome
The investigators have previously demonstrated that Advanced Glycation End products (AGEs) are associated with several chronic diseases in humans and that blood AGE levels can be significantly reduced by simply changing the way…
- Trial name
- NCT01363141
- Testing
- Regular AGE Diet, Low AGE Diet
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sickle Cell Disease
Regional Anesthesia for Sickle Cell Crisis Using Ultrasound in The Emergency Department: Phase I
The hypothesis of this study is: Femoral nerve blocks can feasibly be performed on patients with Sickle Cell Disease and painful crisis in the Emergency Department.
- Trial name
- RESCUED (NCT01256281)
- Testing
- Femoral Nerve Block
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Psychotic Disorders
Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia
This study will assess the effectiveness of pimozide in enhancing the effects of clozapine in the treatment of schizophrenia.
- Trial name
- NCT00158223
- Testing
- Pimozide
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Post-Traumatic Stress Disorder
Effectiveness of Trauma-Focused Cognitive Behavioral Therapy in Treating Children With Post-Traumatic Stress Disorder
This study will compare the effectiveness of trauma-focused cognitive behavioral therapy versus standard care in treating children with post-traumatic stress disorder.
- Trial name
- NCT00614068
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT), Treatment as usual (TAU)
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autistic Disorder
Study of Fluoxetine in Adults With Autistic Disorder
This is a study to determine the effect of fluoxetine in the treatment of adult autism and on functional ability and behavior associated with autism. Evidence suggests abnormal serotonin function in autism.
- Trial name
- NCT00027404
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Common Variable Immunodeficiency
Randomized Study of Polyethylene-Glycol-Conjugated Interleukin 2 in Patients With Common Variable Immunodeficiency
OBJECTIVES: I. Determine whether polyethylene-glycol-conjugated interleukin 2 (PEG-IL-2) can reduce the number of infections in patients with common variable immunodeficiency. II.
- Trial name
- NCT00004695
- Testing
- PEG-interleukin-2
- Volunteers
- 48 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dystonia
Deep Brain Stimulation in Treating Patients With Dystonia
RATIONALE: Dystonia is a disorder in which the muscles that control voluntary movements are persistently or intermittently contracted (not relaxed).
- Trial name
- NCT00004421
- Testing
- implanted pulse generator
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autism
Randomized Study of Fluoxetine in Children and Adolescents With Autism
OBJECTIVES: I. Evaluate the efficacy of fluoxetine on social and language deficits, global severity and compulsive dimensions of children and adolescents with autism. II.
- Trial name
- NCT00004486
- Testing
- fluoxetine
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke, Transient Ischemic Attack
Preventing Recurrent Stroke in Minority Populations
This study focuses on causes of under-use of secondary stroke preventive measures demonstrated in randomized clinical trials to be efficacious, but not appropriately utilized in urban, minority populations.
- Trial name
- NCT00211731
- Testing
- Chronic Disease Self Management Course
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pre-diabetes
Effectiveness Study of Community-Based, Peer-Led Education on Weight Loss and Diabetes
The purpose of this study is to compare the effectiveness of a peer-led community-based lifestyle intervention, versus usual care, in achieving weight loss and prevention of diabetes among overweight adults with pre-diabetes in…
- Trial name
- HEED (NCT01004848)
- Testing
- Peer-Led Lifestyle Education on Weight Loss
- Where
- United States
- Volunteers
- 402 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Stroke Recurrence, Transient Ischemic Attack
Prevent Return of Stroke Study
The purpose of this study is to evaluate if a peer-led stroke recurrence prevention intervention, versus usual care, will help reduce risk factors for recurrent strokes among adults in Harlem.
- Trial name
- NCT01027273
- Testing
- Prevent Return of Stroke
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Screening Colonoscopy
Peer Patient Navigation for Colon Cancer Screening
Cancer health disparities related to race and ethnicity are among the most serious problems facing the US health care system. A recent institute of medicine report stated that such disparities are seen at every level of health…
- Trial name
- NCT02194959
- Testing
- Peer PN, Pro PN
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pulmonary Disease, Cardiac Disease
World Trade Center (WTC) CHEST
This project will evaluate the effects of World Trade Center (WTC) exposure in WTC responders 10-13 years following the events of 9/11.
- Conditions
- Pulmonary Disease, Cardiac Disease, Cardiopulmonary Disease, Obstructive Sleep Apnea
- Trial name
- NCT01466218
- Where
- United States
- Volunteers
- 1,012 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Hip Fractures
Improving Pain and Function in Hip Fracture
The purpose of this study is to compare two different methods of treating pain after a hip fracture.
- Trial name
- NCT00749489
- Testing
- Femoral Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 164 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ability to Influence Behavior, Information Systems
Will a Real Time Advisory for Double Low State Change Clinical Behavior and Impact Outcomes
The objective of this study is to use a decision-support system combined with an electronic anesthesia record to detect double low clinical conditions (Mean Arterial Pressure (MAP) < 75 mmHg, and Bispectral Index (BIS) < 45) and…
- Trial name
- NCT01545596
- Testing
- Notification Group
- Where
- United States
- Volunteers
- 20,237 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Type 1 Diabetes Mellitus
Detection of C-peptide in Youth With Longstanding Type 1 Diabetes Mellitus
Background Type 1 diabetes is characterized by pancreatic beta-cell destruction and an inability to synthesize insulin. Connecting peptide (C-peptide) is formed from the same precursor as insulin and is produced in equimolar…
- Trial name
- NCT02131675
- Testing
- Boost shake
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Head and Neck Cancer, Oropharyngeal Cancer
Role of Immune Activation in Response of Head and Neck Squamous Cell Carcinoma to Therapy
The purpose of this study is to investigate the role of the immune system in the response of squamous cell cancers of the head and neck to treatment that includes radiation therapy.
- Conditions
- Head and Neck Cancer, Oropharyngeal Cancer, Human Papillomavirus, Squamous Cell Cancer
- Trial name
- NCT01358097
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai