Clinical trials: in Pakistan
Gamification in Health Education
Effect of Gamification on Orthodontic Knowledge Retention Among Dental Students
The goal of this clinical trial is to find out if a modern teaching method: Gaming can be used as an effective teaching tool to impart knowledge of orthodontics to final year students of dentistry as compared to another popular…
- Trial name
- NCT07479342
- Testing
- Gamification, LGIS
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Foundation University Islamabad
Diabetic Foot, Diabetic Neuropathies
3D Printed vs Ready-to-Wear Insoles for Diabetic Neuropathy
Diabetic neuropathy is a condition caused by chronic high blood glucose levels that damage nerves over time, frequently causing abnormal plantar pressure and increasing the risk of foot ulcers and impaired mobility.
- Trial name
- 3DP-DPN (NCT07641764)
- Testing
- 3D Printed Customized Insole, Ready-to-Wear Insole
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- University of Faisalabad
HIV - Human Immunodeficiency Virus, Psychological Distress
Comparison of Acceptance and Commitment Therapy and Cognitive Behavior Therapy: Managing Psychological Distress and Its Multifaceted Impact on Stigmatization, Psychological Wellbeing, Social Support and Treatment Adherence in HIV/AIDS Patients
This is a randomized controlled trial comparing Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT) for HIV/AIDS patients at Sheikh Zayed Hospital.
- Trial name
- HIV CBT ACT (NCT07652918)
- Testing
- CBT, ACT+ Standard Care
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sadia Batool
CTS, Carpal Tunnel Syndrome (CTS)
Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
- Trial name
- NCT07653789
- Testing
- Combined Intervention Group, Neuromobilization Group, Tendon Gliding Exercise Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Postoperative Pain
Comparison of Intraperitoneal Bupivacaine and Saline Irrigation for Pain Relief After Laparoscopic Cholecystectomy
This randomized clinical trial compared intraperitoneal irrigation of bupivacaine(a local anesthetic) vs a control group receiving normal saline for relief of post operative pain following laparoscopic gallbladder surgery.
- Trial name
- NCT07650760
- Testing
- Bupivacain, Saline (0.9% NaCl)
- Where
- Pakistan
- Volunteers
- 106 people
- Sponsor
- Wah Medical college , POF hospital
Preterm Labor
Threatened Preterm Labour: Vaginal Progesterone Versus Nifedipine
So, a number of studies have been conducted worldwide to find a suitable agent for arresting threatened preterm labor. The current study is planned to examine the effectiveness of nifedipine and progesterone in the treatment of…
- Trial name
- NCT07649668
- Testing
- Vaginal progesterone 200mg daily, Nifedipine 20 Mg
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- Dr Mudassar Saeed Pansota
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Emergency Laparotomy, Intestinal Obstruction
Enhanced Recovery Versus Standard Care After Emergency Abdominal Surgery in Patients Requiring Emergency Laparotomy
This study aims to compare an Enhanced Recovery After Surgery (ERAS) protocol with conventional postoperative care in adults undergoing emergency laparotomy for intestinal obstruction or intestinal perforation.
- Conditions
- Emergency Laparotomy, Intestinal Obstruction, Intestinal Perforation, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT07650461
- Testing
- Enhanced Recovery After Surgery, Conventional Postoperative Care
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Duration of Analgesia, Pain Score
Evaluation of Intrathecal Hyperbaric Bupivacaine With Dexmedetomidine in Adults Undergoing Perianal Surgery
The aim of this study is to evaluate the effects of adding 5-mcg dexmedetomidine to hyperbaric bupivacaine in our population as it has never been published before, to enhance the duration of analgesia after perianal procedures…
- Trial name
- DEX-BUP (NCT07651488)
- Testing
- Dexmedetomidine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Liaquat National Hospital & Medical College
Chemotherapy Induced Oral Mucositis
Effect of Oral Ice Chips to Prevent Chemotherapy-Induced Oral Mucositis in Patient With Solid Tumor Treated With 5 Fluorouracil and Methotrexate
The goal of this randomized controlled clinical trial is to determine whether oral cryotherapy using ice chips can prevent and reduce the incidence and severity of chemotherapy-induced oral mucositis in adult cancer patients…
- Trial name
- NCT07327476
- Testing
- Oral Cryotherapy (Ice Chips), Standard Oral Care (Mouthwash)
- Where
- Pakistan
- Volunteers
- 102 people
- Sponsor
- University of Health Sciences Lahore
Hemodynamic Responses During Tracheal Extubation, Peri-extubation Hypertension
Comparative Study About The Effect Of Dexmedetomidine Vs Lignocaine On Hemodynamic Stability During Tracheal Extubation, Especially In Resource Limited Populations
This randomized, double-blind controlled trial aims to compare the effectiveness of intravenous dexmedetomidine (0.5 µg/kg) and lignocaine (1.5 mg/kg) in attenuating hemodynamic responses during tracheal extubation in adult…
- Conditions
- Hemodynamic Responses During Tracheal Extubation, Peri-extubation Hypertension, Peri-extubation Tachycardia
- Trial name
- NCT07651657
- Testing
- Tracheal Extubation
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Mayo Hospital Lahore
Iron Deficiency Anemia, Iron Deficiency Anemia Treatment
Effectiveness of Oral Iron Therapy in Iron Deficiency Anemia With Daily vs Alternate Day Dosing
Treating iron deficiency anemia in children with daily and alternate day oral iron therapy
- Trial name
- NCT07267975
- Testing
- Ferrous sulphate
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Parkinson Disease, Neuro-Degenerative Disease
Conventional Physical Therapy Action Observation Therapy on Freezing of Gait and Functional Mobility in Parkinson's Disease
The goal of this study is to determine the effects of action observation therapy with conventional physical therapy on freezing gait and functional limitation in participants with Parkinson's disease.
- Trial name
- NCT07244900
- Testing
- Conventional Physical Therapy, Action Observation plus conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- University of Lahore
Seizure Disorder Generalized Tonic Clonic
Comparing the Outcome of Buccal Midazolam and Intramuscular Midazolam in Children Presenting With Seizures.
The goal of this clinical trial(Quasi Experimental) is to compare efficacy of oral midazolam over intra-muscular Midazolam in children suffering from seizures.
- Trial name
- NCT07626255
- Testing
- Midazolam
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Community Acquired Pneumonia, Childhood Pneumonia
3 vs. 5 Days of Amoxicillin for Childhood Pneumonia: An RCT
Pneumonia is the most common infection in children and leading to most common cause of mortality and morbidity in in children globally. Bacterial cause is mostly streptococcus pneumonia in children of 3 months to 5 years of age.
- Trial name
- Pnemonia (NCT07647835)
- Testing
- Amoxicillin
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Khyber Teaching Hospital
Epidural Dosage of Lidocaine Bupivacaine in Lower Limb Surgeries
Comparison of Different Epidural Lidocaine-Bupivacaine Mixtures for Lower Limb Surgeries
This randomized controlled trial will evaluate different epidural lidocaine-bupivacaine mixtures in patients undergoing lower limb surgery at a tertiary care hospital in Karachi, Pakistan.
- Trial name
- LBM-LLS (NCT07648784)
- Testing
- Lidocaine-Bupivacaine Epidural Mixture (High-dose Lidocaine)
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Congenital Syndactyly of Hand
Comparison of Outcomes of Plantar vs Groin Full-Thickness Skin Graft for Correction of Congenital Syndactyly of Hand
Congenital syndactyly is a condition present at birth in which two or more fingers are joined together. Surgical correction was performed to separate the fingers, improve hand appearance, and support better hand function.
- Trial name
- NCT07647562
- Testing
- Plantar Full-Thickness Skin Graft, Groin Full-Thickness Skin Graft
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Sheikh Zayed Medical College
Cervical Spinal Cord Injury, Cervical Cord Injuries Spinal
Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries
This randomized clinical trial aims to evaluate the effectiveness of combining Low Volume Nose Resistance Breathing Exercises (LVNRBE) with Incentive Spirometry (IS) on respiratory outcomes in patients with cervical spinal cord…
- Trial name
- NCT07645027
- Testing
- Acapella device plus Incentive Spirometry, conventional respiratory physiotherapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Chronic Non-Specific Low Back Pain
Comparison of High-Intensity Interval Training With Moderate-Intensity Continuous Training in Chronic Non-Specific Low Back Pain Patients
The goal of this clinical trial is to compare the HIIT with MICT in chronic non-specific low back pain patients. The main questions it aims to answer are: The broad aim of the study is to compare HIIT with MICT in pain reduction…
- Trial name
- NCT07645859
- Testing
- Brisk walk and jog, Normal walk
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Chronic Low-back Pain (cLBP)
Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain
Chronic low back pain (CLBP) is a multifactorial condition influenced by physical, psychological, and social factors. Conventional physical therapy primarily targets biomechanical impairments, often neglecting psychosocial…
- Trial name
- NCT07280806
- Testing
- Biopsychosocial model based care, Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
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