Clinical trials: in Ethiopia
Peer Support Intervention
Effect of a Peer Support Intervention on Glycemic Control and Economic Burden Among Patients With Diabetes
Diabetes imposes a growing global burden due to rising care costs and reduced quality of life from its complications. Managing the disease remains challenging for many patients, highlighting the need for effective, scalable…
- Trial name
- PSI (NCT07499375)
- Testing
- Peer led educational intervention program
- Where
- Ethiopia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Breast Cancer
Clinical Breast Examination and Patient Navigation Intervention in Sub-Saharan Africa
Brief summery Prolonged presentation, along with diagnostic and treatment delays, remain significant problems for breast cancer care in sub-Saharan Africa , primarily due to low health-seeking behaviour, lack of access, long…
- Trial name
- NCT07023198
- Testing
- Clinical breast examination and Navigation
- Where
- Ethiopia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Diarrhea, Stunting
Effect of Water, Sanitation and Hygiene Educational Intervention on Incidence of Diarrhea and Childhood Stunting Among Under Five Children in Bule Hora Wereda, Southern Ethiopia
Background: Childhood malnutrition and diarrhea remains life-threatening, yet these conditions are preventable. Water, Sanitation, and Hygiene (WASH) interventions are among the most effective measures against diarrhea and…
- Conditions
- Diarrhea, Stunting, Children Under 5 Years
- Trial name
- NCT07867860
- Testing
- WASH Education Intervention
- Where
- Ethiopia
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Bule Hora University
Patient Safety, Patient Safety Education
Patient Safety Competency-Building Program for Healthcare Professionals in Pediatric Cardiac Critical Care in Ethiopia
This study aims to develop and evaluate a patient safety competency-building program for healthcare professionals involved in pediatric cardiac critical care in Ethiopia.
- Trial name
- NCT07844369
- Testing
- Patient Safety Competency-Building Program
- Where
- Ethiopia
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Woong-Han Kim
Dietary Intake, Sexual and Reproductive Health
Advancing Female University Students' Health Through Mobile Technology in Ethiopia
Background: Female university students in Ethiopia experience a high burden of sexual and reproductive health, nutrition, and psychosocial problems, exacerbated by limited access to essential health services and support.
- Conditions
- Dietary Intake, Sexual and Reproductive Health, Psychosocial Wellbeing
- Trial name
- EMPOWER (NCT07746791)
- Testing
- Behavioural change intervention will be provided through mobile application, Routine care
- Where
- Ethiopia
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Bahir Dar University
Tuberculosis, Pulmonary
Digital Health Intervention to Improve TPT Uptake
Despite the evidence of the prevention and control measures of tuberculosis (TB), it still has an impact on the health, social, and economic aspects of the population.
- Trial name
- DHiTPT (NCT07313995)
- Testing
- Digital health intervention
- Where
- 14 sites in Ethiopia
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Arba Minch University
Acute Malnutrition, Severe, Malnutrition, Child
Increasing the Coverage of Severe Acute Malnutrition (SAM) Treatment in Ethiopia
The R-SWITCH intervention aims to address the low coverage of treatment for severe wasting (SAM) by leveraging existing community groups to deliver an integrated package focused on prevention, screening, referral, and treatment…
- Conditions
- Acute Malnutrition, Severe, Malnutrition, Child, Wasting
- Trial name
- R-SWITCH (NCT06380504)
- Testing
- R-SWITCH integrated intervention package
- Where
- Ethiopia
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Malaria Fever
Non-invasive Malaria Diagnostic Data Collection in Ethiopia
This project supports the development of a non-invasive diagnostic tool for malaria, focusing on validating the link between VOCs (volatile organic compounds) and malaria infection using thermodynamic sensors.
- Trial name
- NCT07456969
- Where
- Ethiopia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Breast Cancer
System-integrated Point-of-Care Ultrasound in Breast Cancer Screening
To assess the feasibility, safety, and clinical performance of community-based breast cancer screening incorporating clinical breast exam and short-termed trained examiners performing AI-supported breast POCUS for triage in…
- Trial name
- SPRING (NCT07462351)
- Testing
- AI
- Where
- Ethiopia
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Region Skane
Leishmaniasis, Cutaneous, Leishmaniasis
Ex Vivo Immunogenicity Screening of Vaccine Candidate Antigen Combinations in Ethiopian Patients With Leishmaniasis
This study assesses the immunoprevalence (presence of the induced T-cell response across different patients (and thus HLA types) of six prioritized IPX-derived Leishmania antigens, using Good Laboratory Practice-grade soluble…
- Conditions
- Leishmaniasis, Cutaneous, Leishmaniasis, Leishmaniasis, Visceral, Immunogenicity
- Trial name
- LEISHVAC (NCT07783243)
- Where
- 2 sites in Ethiopia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Folate Deficiency, Vitamin B 12 Deficiency
Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls
Folic acid and vitamin B12 play an interdependent role in key cellular processes, namely deoxyribonucleic acid synthesis, cell division, red blood cell formation, and nervous system myelination.
- Conditions
- Folate Deficiency, Vitamin B 12 Deficiency, Anemia, Megaloblastic, Cognitive Development
- Trial name
- NCT06100146
- Testing
- Folic acid and vitamin B12 fortified flour, Unfortified cereal flour
- Where
- 2 sites in Ethiopia
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- University Ghent
Athletic Injuries
Machine Learning-Guided Training for Elite Athletes (MLGT)
Plaintext The purpose of this study is to evaluate whether a personalized training protocol driven by machine learning can successfully reduce time-loss sports injuries and enhance athletic performance in elite athletes.
- Trial name
- MLGT (NCT07683091)
- Testing
- Adaptive Machine Learning Workload Optimization
- Where
- 2 sites in Ethiopia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Debre Berhan University
Cervical Carcinoma, Human Papilloma Virus (HPV)
Leveraging Project ECHO for Improved Cervical Cancer Screening in Ethiopia
Project TICHILALECH ("she can" in Amharic), a five-year, implementation science study, is focused on improving cervical cancer screening, triage, and treatment and integration with human immunodeficiency virus (HIV) care at five…
- Trial name
- NCT07678047
- Testing
- TICHILALECH ECHO
- Where
- Ethiopia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Prenatal Exposure Delayed Effects
Nutrition and Inflammation in Pregnancy: Impacts on Early Human Brain Development in Ethiopia
The goal of this observational child follow-up study is to examine the effects of prenatal nutrition and infection management interventions on long-term child neurodevelopment.
- Trial name
- NCT06296238
- Where
- Ethiopia
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Brown University
Maternal Behavior
Evaluation of Prototype Solutions for Optimizing Maternal Health Behaviors
This study is a three-year implementation research project that aims to develop and test the effectiveness and acceptability of interventions to promote three outcomes: institutional delivery, antenatal care, and iron-folic acid…
- Trial name
- NCT05907720
- Testing
- Human-centered design prototype solutions for vulnerable pregnant women
- Where
- Ethiopia
- Volunteers
- 1,468 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Trachoma
Sanitation, Water, and Instruction in Face-washing for Trachoma I/II
SWIFT I is a series of 3 cluster-randomized trials designed to assess several alternative strategies for trachoma control in communities that have been treated with many years of mass azithromycin distributions.
- Trial name
- SWIFT I/II (NCT02754583)
- Testing
- Water, sanitation, and hygiene (WASH) intervention, Standard of care WASH intervention, Azithromycin
- Where
- Ethiopia
- Volunteers
- 47,605 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Adolescent Behavior, Gender
GAGE Act With Her-Ethiopia Evaluation
This study evaluates the impact of Act With Her Ethiopia (AWH-E), a gender transformative multi-level program that aims to improve the lives of young adolescent boys and girls.
- Trial name
- NCT03890237
- Testing
- Her Spaces, Act With Her, Act With Her + Asset Transfer
- Where
- 3 sites in Ethiopia
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- George Washington University
Post Partum Depression
Prevalence and Determinant Factors of Postpartum Depression Among Mothers Visiting Postnatal and Immunization Clinics in Selected Public Health Institutions, Mekelle, Tigray
This study looks at depression among mothers after childbirth (also called postpartum depression) in Mekelle City, Tigray, Ethiopia.
- Trial name
- NCT07563712
- Where
- Ethiopia
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Mekelle University
Maternal and Child Health, Maternal Nutrition
Social Networks for Improving Maternal & Child Health
Brief Summary: Improving Maternal and Child Health via Indigenous Structures The goal of this cluster randomized controlled community trial is to assess the effect of community-based interventions using indigenous community…
- Trial name
- SoNIMCH (NCT07522047)
- Testing
- Community-based Health and Nutrition Counseling via Indigenous Social Support Structures (ISSS)
- Where
- Ethiopia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Bahir Dar University