Clinical trials: Urinary Tract Infections
Urinary Tract Infections
Phase II Proof of Concept Study in Uncomplicated UTI
A study of the efficacy and safety of MPC-SHRC for the relief of symptoms associated with uncomplicated urinary tract infections.
- Trial name
- NCT03129295
- Testing
- MPC-SHRC
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Mission Pharmacal
Critical Illness, Burns
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
Catheter-associated urinary tract infections (CAUTI) are the most common nosocomial infections in critically ill patients and are responsible for high morbidity rates, increased hospital stays and associated costs.
- Conditions
- Critical Illness, Burns, Surgery, Urinary Tract Infections
- Trial name
- CAB (NCT03816384)
- Testing
- Standard of Care, DLC Group, DLCS Group
- Sponsor
- Potrero Medical
Recurrent Urinary Tract Infection
Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream
Vaginally applied estrogen has been shown to decrease the incidence of Recurrent Urinary Tract Infection (rUTI) in post-menopausal women. However, prior studies have shown the compliance rate for topical estrogen cream is low.
- Trial name
- NCT05723601
- Testing
- Estradiol vaginal cream, Estradiol Vaginal Tablet
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Dysfunction, Lower Urinary Tract Symptoms
School-Based Bladder Health Intervention
The aim of this study is to promote healthy bladder behaviors among school children. We hypothesize that a combination of bladder health education and awareness events, additional resources such as a water station to support…
- Conditions
- Urinary Dysfunction, Lower Urinary Tract Symptoms, Urinary Tract Infections, Urinary Tract Infections in Children
- Trial name
- NCT06273098
- Testing
- Bladder Health Education
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Cystitis, Urinary Tract Infections
Treatment and/or Prevention of Urinary Tract Infections
The purpose of the study is to determine the effect of an investigational oral rinse in reducing uropathogens and treating uncomplicated urinary tract infections.
- Trial name
- UTI (NCT00801021)
- Testing
- Frio Mouth Rinse
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Biomedical Development Corporation
Idiopathic Overactive Bladder, Postoperative Urinary Tract Infection
Antibiotic Prophylaxis for Bladder Botox
Injection of Botox into the bladder is a common treatment for overactive bladder. Postoperative bladder infection is one of the more frequently reported complications of this procedure.
- Trial name
- NCT04444440
- Testing
- Ciprofloxacin
- Where
- Canada
- Volunteers
- 202 people
- Sponsor
- University of Alberta
Urinary Tract Infections
Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)
The study will be conducted to evaluate the therapeutic response (combined per participant microbiological and clinical response) of oral gepotidacin compared to oral nitrofurantoin for treatment of uncomplicated UTI (acute…
- Trial name
- NCT04187144
- Testing
- Gepotidacin, Nitrofurantoin
- Where
- 113 sites in United States, Australia and 4 more
- Volunteers
- 1,606 people
- Sponsor
- GlaxoSmithKline
Intravesical Bacteriophage Treatment for Urinary Tract Infections
Bacteriophages for Treating Urinary Tract Infections in Patients Undergoing Transurethral Resection of the Prostate
Urinary tract infections are among the most prevalent microbial diseases and their financial burden on society is substantial. The use of bacteriophages against bacterial pathogens has gained over the last years a renewed…
- Trial name
- NCT03140085
- Testing
- PYO Phage, Antibiotics, Sterile bacteriology media
- Where
- Georgia
- Volunteers
- 97 people
- Sponsor
- Balgrist University Hospital
Overactive Bladder, Overactive Detrusor
Sensitivity of Extended Cultures in Diagnosing Urinary Tract Infections
There is some evidence to suggest standard urine cultures may not be adequate in identifying patients with low grade urinary tract infections.
- Conditions
- Overactive Bladder, Overactive Detrusor, Urgency-Frequency Syndrome, UTI
- Trial name
- NCT03080389
- Testing
- Extended Urine Culture
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Urinary Tract Infections, Cesarean Section; Infection
Caesarean Delivery With or Without an Indwelling Bladder Catheter
The aim of this study is to compare the incidence of catheter associated culture-based urinary tract infection (UTI) after elective CD with or without preoperative placement of a urinary catheter.
- Trial name
- NCT03672214
- Testing
- Without placement of indwelling catheter, With placement of indwelling catheter
- Where
- Denmark
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Urinary Tract Infections, Bladder Cancer
Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB)
Antimicrobial prophylaxis in urological procedures is aimed to reduce the risk of local and systemic postoperative infections such as urinary tract infection or surgical site infection.
- Conditions
- Urinary Tract Infections, Bladder Cancer, Urologic Surgical Procedures
- Trial name
- NCT04209192
- Testing
- Fosfomycin Tromethamine 3G Sachet, Amikacin
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Urinary Tract Infections
Urinary Tract Infections in Older Persons Admitted to a Psychogeriatric Ward
Urinary tract infections are one of the most common types of infections in older persons. The general aim of this study is to improve the epidemiological knowledge and develop a better diagnostic algorithm for urinary tract…
- Trial name
- UTI_UCP (NCT02368847)
- Testing
- Diagnostic tests
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Surgical Wound Infection, Cystitis
The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study
All surgical procedures carry with them the risk of infection. Even a minor infection can extend the hospitalization after cardiac surgery. The average minimum increase in length of stay for a single infection is three days.
- Conditions
- Surgical Wound Infection, Cystitis, Bacteremia, Pneumonia
- Trial name
- NCT00164099
- Testing
- Synbiotic 2000
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Beth Israel Medical Center
Cystitis, Recurrent, Urinary Tract Infections
Microbiome-Modulating Prophylaxis RCT: Antibiotic vs Gynoflor in Postmenopausal Women With Recurrent Cystitis
This open-label, parallel-group randomized controlled trial compares two prophylaxis strategies for recurrent urinary tract infection (rUTI) in postmenopausal women: (1) nightly oral nitrofurantoin 100 mg for 6 months versus (2)…
- Trial name
- microbiome (NCT07186465)
- Testing
- Nitrofurantoin, Gynoflor
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Multiple Sclerosis, Urinary Tract Infections
Cranberry for Prevention of Urinary Tract Infections in Multiple Sclerosis Patients
Bladder dysfunction occurs at some time in most patients with multiple sclerosis and these patients are prone to have recurrent urinary tract infections.
- Conditions
- Multiple Sclerosis, Urinary Tract Infections, Bladder Dysfunction
- Trial name
- CANNEBERGE (NCT00280592)
- Testing
- Cranberry
- Where
- 10 sites in France
- Volunteers
- 171 people
- Sponsor
- Rennes University Hospital
Urinary Tract Infections, Catheter-Related Infections
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery…
- Trial name
- NO-UTI (NCT02358993)
- Testing
- methenamine hippurate, Ciprofloxacin
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Urinary Retention, Urinary Tract Infection (Diagnosis)
How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding
At least ten percent of patients have postpartum urinary retention or difficulty urinating after birth, which can cause incontinence and other urinary problems long-term.
- Conditions
- Urinary Retention, Urinary Tract Infection (Diagnosis), Postpartum Acute Urinary Retention, Postpartum Care
- Trial name
- NCT07125326
- Testing
- Intermittent catheterization, Continuous catheterization
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Upper Respiratory Tract Infections, Urinary Tract Infections
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care
To evaluate the effect of a continuous postal and web-based feedback and peer comparison system of individual antibiotic prescription rates on the prescription behaviour of primary care physicians in Switzerland.
- Trial name
- NCT01773824
- Testing
- Antibiotic prescription feedback, No Feedback
- Where
- Switzerland
- Volunteers
- 2,900 people
- Sponsor
- University Hospital, Basel, Switzerland
Neurogenic Bladder, Catheter-Related Infections
Antiseptic-coated Intermittent Urinary Catheter
Study design is a prospective, randomised, double-blind, and interventional. Primary aim of the study is to investigate efficacy of antiseptic-coated intermittent hydrophilic urinary catheters in prevention and reduction of…
- Trial name
- GuardianCath (NCT02697162)
- Testing
- Antiseptic-coated catheter, Hydrophilic catheter, Octenidine chloride
- Where
- Croatia
- Sponsor
- Children's Hospital Zagreb
Otorhinolaryngologic Diseases, Respiratory Tract Infections
Antibiotic Education for Children in an Emergency Care Unit
The purpose of this study is to determine if a patient education in acute condition about the intake of oral solution antibiotic in children under 6 year-old are effective to improve the satisfaction about the therapeutic…
- Conditions
- Otorhinolaryngologic Diseases, Respiratory Tract Infections, Pyelonephritis, Urinary Tract Infections
- Trial name
- ACHEEN (NCT00948779)
- Testing
- antibiotic education for children in an emergency care unit
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris