Clinical trials: Upper Endoscopy
Cirrhosis
Study of Two Fasting Procedures Before Gastroscopy: 6 Hours Versus 2 Hours for Clear Fluids
Upper gastrointestinal endoscopy is the key examination for screening for precancerous and cancerous lesions of the esophagus and stomach.
- Trial name
- GASTROPREP (NCT03706846)
- Testing
- fasting
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
All Patients With Upper GIT Symptoms and Underwent Upper Endoscopy
Pattern Of Endoscopic Findings In Patients Underwent Upper Endoscopy In Sohag University Hospital
Diseases associated with upper gastrointestinal tract (UGIT) are common and associated with significant morbidity and mortality globally.
- Trial name
- NCT05820061
- Testing
- upper endoscopy
- Where
- Egypt
- Volunteers
- 800 people
- Sponsor
- Sohag University
Advanced Colorectal Neoplasms, Throat Cancer
Fecal Screening Assay for Taiwanese Population
Fecal occult blood test (FOBT) is a convenient tool for the screening of asymptomatic gastrointestinal (GI) bleeding while 「guaiac-based fecal occult test (G-FOBT) 」 is increasingly replaced by the use of an 「immunochemical-based…
- Conditions
- Advanced Colorectal Neoplasms, Throat Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT01341197
- Testing
- Fecal immunochemical test, guaiac fecal occult-blood test, and Helicobacter pylori stool antigen test
- Where
- Taiwan
- Volunteers
- 3,172 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Esophageal Motility Disorders
Observational Field Study of Acute Esophageal Food Bolus Impaction by Mean Esophageal Manometry and 24h-pH-monitoring
The aim of this study is to evaluate standard investigations performed in patients with bolus impaction in a prospective observational field study. In bolus impaction, ingested food boluses have to be endoscopically removed.
- Trial name
- NCT01447823
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Cirrhosis, Esophagogastric Varices
Clinical Management Strategies for Patients With Cirrhosis and Esophagogastric Varices Complicated by Early-stage Upper Gastrointestinal Cancer
Managing early-stage upper gastrointestinal cancer in patients with liver cirrhosis and esophagogastric varices (EGV) poses substantial clinical challenges.
- Conditions
- Cirrhosis, Esophagogastric Varices, Early-stage Upper Gastrointestinal Cancer
- Trial name
- NCT07368309
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Renmin Hospital of Wuhan University
Upper Gastrointestinal Disorder
Performance Characteristics and Technical Outcomes of Single-use vs. Reusable Gastroscopes Evaluated in the OR
The goal of this clinical trial is to investigate whether single-use gastroscopes are as good as reusable gastroscopes when used in the operation theater in all patients where gastroscopy in the operation theater is indicated.
- Trial name
- NCT06581016
- Testing
- Ambu aScope Gastro, Ambu aScope Gastro Large, Diagnostic gastroscopes, Olympus
- Where
- Denmark
- Volunteers
- 700 people
- Sponsor
- Zealand University Hospital
Gastroesophageal Reflux Disease
Endoloop Mediated Cardioplication to Treat Gastroesophageal Reflux Disease
Endoscopic full-thickness plication (EFTP) of cardia/fundus has been shown effective in treating GERD patients. However, EFTP requires proprietary equipment that are not available in many countries.
- Trial name
- NCT06153901
- Testing
- endoloop mediated cardioplication (ECLC) procedure
- Volunteers
- 35 people
- Sponsor
- Qilu Hospital of Shandong University
Gastrointestinal Endoscopy
Moderate Sedation Combined With Acupuncture Anesthesia in Gastroscopy and Colonoscopy on Screening Research
The purpose of this study is mainly about the feasibility and rationality of moderate sedation combined with acupuncture anesthesia in the application of gastroscopy and colonoscopy ,Then we evaluate the effectiveness and…
- Trial name
- NCT05485064
- Testing
- fentanyl, eletroacupuncture(transcutaneous electrical acupuncture point stimulation ), remimazolam
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
High Risk Superficial Upper Urinary Tract Transitional Cell Carcinoma, Endoscopic Surgical Procedure
Pembrolizumab in Combination With BCG After Ablation in Patients With UUTTCC Without Nephroureterectomy
PURPOSE: This study is being conducted to test the safety of the study drug Pembrolizumab, also known as MK-3475, at different dose levels in combination with the current therapy, (BCG), for superficial upper urinary tract…
- Conditions
- High Risk Superficial Upper Urinary Tract Transitional Cell Carcinoma, Endoscopic Surgical Procedure, Transitional Epithelial Cells
- Trial name
- NCT03345134
- Testing
- MK-3475 and BCG
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shaheen Alanee
Gastrointestinal Diseases
An Observer Blinded Comparison of MACE and Conventional Upper Gastrointestinal Endoscopy in Upper GI Bleeding
Gastroscopy (OGD) is a useful test for investigating a variety of suspected upper GI disorders. But it is uncomfortable for patients and incurs the risk of intubation and sedation, plus a large proportion of procedures reveal…
- Trial name
- MACE (NCT02690376)
- Testing
- Magnetic Assisted Capsule Endoscopy
- Where
- 2 sites in United Kingdom
- Volunteers
- 23 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Upper Tract Urothelial Carcinoma Receiving Kidney-sparing Therapy, Upper Tract Urothelial Carcinoma
Multimodal Kidney-Sparing Strategy for High-Risk Upper Tract Urothelial Carcinoma
UTUC is a cancer that develops in the lining of the kidney or ureter. The standard treatment is radical nephroureterectomy, which removes the kidney and ureter.
- Trial name
- NCT07504939
- Testing
- SBRT
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Peking University First Hospital
Dyspepsia
Functional Dyspepsia - Effect of Acid-Reducing Treatment and Information.
Study title: Functional dyspepsia -- effect of acid reducing treatment and individualized information. Summary: 15-20% of all people experience dyspepsia each year.
- Trial name
- NCT00437346
- Testing
- Individualized and comprehensive information, Lanzo Melt
- Where
- 5 sites in Norway
- Volunteers
- 35 people
- Sponsor
- Helse Fonna
Upper Aerodigestive Tract Neoplasms, Upper AerodigestiveTract Cancer
AI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions
This is a prospective observational clinical study designed to evaluate the performance of artificial intelligence (AI) algorithms applied to upper aerodigestive tract (UADT) video-endoscopy.
- Conditions
- Upper Aerodigestive Tract Neoplasms, Upper AerodigestiveTract Cancer, Upper Aero-digestive Tract (UADT) Neoplasm, Squamous Cell Carcinoma
- Trial name
- H&NANCE (NCT07596355)
- Where
- 3 sites in Belgium, Italy and 1 more
- Volunteers
- 283 people
- Sponsor
- Istituto Italiano di Tecnologia
Hepatic Encephalopathy
Trial Comparing Sedation for Endoscopy With Propofol Versus Midazolam in Cirrhotics
To compare effects of sedation for upper gastrointestinal endoscopy with propofol and midazolam on psychometric tests and critical flicker frequency (CFF) in cirrhotics
- Trial name
- NCT01356121
- Testing
- Propofol, Midazolam
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Govind Ballabh Pant Hospital
Intraocular Pressure Changes, Upper Gastrointestinal Endoscopy
Intraocular Pressure Changes During EGD
This prospective observational study evaluates short-term changes in intraocular pressure (IOP) during elective esophagogastroduodenoscopy (EGD) performed under routine sedation.
- Trial name
- ENDO-IOP (NCT07190508)
- Testing
- No Intervention (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Sevim Şenol Karataş
Comprehensive Education
The Impact of Comprehensive Education Before Gastroscopy on Improving the Tolerance of Patients
This clinical trial is being conducted to assess whether the comprehensive education before gastroscopy could reduce the adverse reactions, such as nausea, vomiting and improve patient satisfaction.
- Trial name
- NCT03638752
- Testing
- Comprehensive education group
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Ningbo No. 1 Hospital
Gastroesophageal Reflux Disease, Dyspepsia
Evaluation of Efficiency of Esophageal Capsule Endoscopy in the Screening of Patients With Gastroesophageal Reflux Disease or Dyspepsia as Compared to Upper Endoscopy
The exploration of evocative symptoms of esophageal reflux disease or dyspepsia is based on a relatively invasive endoscopic examination, often badly tolerated, and which, in France, is carried out in 50% of the cases under…
- Trial name
- NCT00217347
- Testing
- Esophageal Capsule Endoscopy
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Colonoscopy
Effect of Butorphanol on Colonoscopy for Patients With Postoperative Visceral Pain
The total incidence of abdominal pain after colonoscopy is almost 50%. Butorphanol is a mixed opioid receptor agonist-antagonist, which has strong sedative and analgesic effects.
- Trial name
- NCT04477733
- Testing
- Butorphanol Injection, Saline
- Where
- China
- Volunteers
- 203 people
- Sponsor
- Beijing Tiantan Hospital
Iron Deficiency Anemia
Gastric Capsule Examination for Iron Deficiency Anaemia
This is a pilot prospective single blind controlled trial comparing magnetically steerable gastric capsule endoscopy to conventional oesophagogastroduodenoscopy in diagnosing upper gastrointestinal pathology in patients with…
- Trial name
- NCT02282553
- Testing
- Magnetically steerable pill camera (Microcam Navi, Intromedic Ltd, Seoul, Korea), Flexible endoscope
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Hypoxemia
Oxygen Delivery Methods of Nasal Catheter on the Incidence of Hypoxemia in Patients With Painless Gastroscopy
In this study, patients undergoing painless gastroscopy were selected to change the nasal catheter oxygen delivery mode to oral oxygen delivery after endoscope implantation, in order to explore the effect of this oxygen delivery…
- Trial name
- NCT06139081
- Testing
- Oxygen delivery mode
- Where
- China
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University