Clinical trials: Unilateral Cleft Palate
Unilateral Cleft Lip and Palate, Cleft Lip
Evaluation of Facial Growth in Two Primary Protocols Used in the Surgical Treatment of Unilateral Cleft Lip and Palate Patients
The purpose of this study is to evaluate which surgical protocol for treating Unilateral Cleft Lip and Palate (UCLP), a single or two stage repair ( with hard palate late closure) will have less impact in mid facial growth.
- Conditions
- Unilateral Cleft Lip and Palate, Cleft Lip, Cleft Palate, Developmental Disabilities
- Trial name
- NCT02329509
- Testing
- two stage palate surgical repair, One stage Palate Surgical repair
- Volunteers
- 64 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Cleft Lip and Palate
Parent's Satisfaction and Evaluation of Postsurgical Outcomes in Unilateral Cleft Lip / Palate Newly Born Infants With / Without Vacuum Formed Nasoalveolar Molding Aligners : A Controlled Clinical Trial
Newborns with unilateral cleft lip/ palate will be treated pre-surgically by Vacuum formed aligners in order to evaluate its effect on Nasoalveolar complex.
- Trial name
- NCT03011489
- Testing
- Vacuum formed aligners
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate Children
Feasibility and Performance of Virtual Software for Virtual Bone Graft Planning in Cleft Patients
Objective: The investigators aim to compare the licensed Brainlab Iplan® software, considered the gold standard, to the 3D slicers and Blender freeware for the segmentation of the unilateral cleft defect, as well as the creation…
- Trial name
- VIR-CLEFT (NCT03994679)
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- AZ Sint-Jan AV
Cleft Lip Palate, Cleft Lip, Unilateral, Complete
Nasoalveolar Molding for Egyptian Cleft Lip Palate Infants
The cleft lip and palate (CLP) is the commonest craniofacial anomaly worldwide. Nasoalveolar molding (NAM) therapy has emerged in the management of CLP as an early presurgical intervention to provide symmetry to severely deformed…
- Trial name
- EgyCleft (NCT03029195)
- Testing
- Nasoalveolar molding therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Unilateral Cleft Lip, Nasoalveolar Molding
Nasolabial Soft Tissue Esthetics and Maxillary Changes in Unilateral Cleft Lip and Palate Using PreSurgical Infant Orthopedics With Different Approaches
The nasal deformity is an abnormality in the appearance and structure of the nose in cleft patients having unilateral cleft lip and palate (UCLP).
- Trial name
- PSIO (NCT05940389)
- Testing
- Naso Alveolar Mold, Taping with nasal elevator:
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Cleft Lip and Palate
Effectiveness of Nasal-alar Elevator Combined With Taping Vs. Taping Alone on Improving the Nose Esthetics and Maxillary Arch Dimensions in Infants With Unilateral Complete Cleft Lip and Palate
This randomized trial is designed to assess the effectiveness of nasal elevator as a presurgical infant orthopedics on improvement of nose esthetics vs taping alone.
- Trial name
- NCT04331379
- Testing
- Nasal Elevator, Taping Alone
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Surgically Repaired Unilateral Cleft Lip and Palate
Evaluation of Arch Dimensions of Children With Surgically Repaired Unilateral Cleft Lip and Palate
The aim of the study is to assess arch dimensions among children with surgically repaired unilateral cleft lip and palate.
- Trial name
- NCT03219021
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Menna Allah Mohammed Awad
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
Patients With Unilateral Cleft Lip With or Without Cleft Palate
A Proposal for a New Classification of Secondary Cleft Lip and Nose Deformities in Repaired Unilateral Cleft Lip
Congenital cleft lip with or without cleft palate is one of the most common congenital malformations with an estimated incidence of about 1 every 500 to 700 live births.
- Trial name
- NCT04972370
- Testing
- Patients with Unilateral Cleft Lip with or without Cleft Palate
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cleft Lip and Palate
Unilateral Cleft Repair in One Surgery With Pure Primary Healing
Retrospective analysis of the current surgical method to repair unilateral cleft lip and palate malformations at our centre
- Trial name
- NCT04108416
- Testing
- Cleft lip and palate repair
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Unilateral Complete Cleft Lip and Palate
Printed Aligners for Nasoalveolar Molding Treatment
study will provide nasoalveolar molding (NAM) treatment, special care for infants born with cleft lip and palate. This novel appliance will help to provide the care in accurate and easy form by help of both digital work flow and…
- Trial name
- NAM (NCT06683560)
- Testing
- : photopolymer resin material "graphy" Tera Harz 85 will be used to print 3D printed aligners for NAM treatment
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Cleft Palate, Unilateral, Complete
Palatal Lengthening Using Buccinator Myomucosal Flaps with Furlow Z-plasty Technique for Primary Cleft Palate Repair
: Cleft palate is a congenital deformity caused by abnormal facial development during intra-uterine life. Worldwide, the prevalence of cleft lip/palate is about 1:1000 live births.
- Trial name
- NCT04346173
- Testing
- furlow z plasty with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Mahmoud Akram
Cleft Lip and Palate
DynaCleft® Effects on Soft Tissues and on Quality of Life for Incomplete Unilateral Cleft Lip Infants
The purpose of this study is to examine the effectiveness of the DynaCleft® system on soft tissues of infants with unilateral incomplete cleft lip and to assess influences on quality of life for infants who underwent DynaCleft®…
- Trial name
- NCT04455035
- Testing
- Comparator: Retrospective Group(Control), Prospective Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cleft Lip and Palate
The Effectiveness of Adhesive Versus Conventional Nasoalveolar Molding on Children With Unilateral Cleft Lip and Palate
The present study will compare the effectiveness of adhesive nasoalveolar molding (GS-NAM) and conventional nasoalveolar molding on the alveolar ridge, nasal, and labial growth in children with unilateral cleft lip and palate.
- Trial name
- NCT06451276
- Testing
- Nasoalveolar molding in unilateral cleft lip and palate
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cleft Lip and Palate
Assessment of Maxillary Arch Depth and Width in a Group of Surgically Repaired Unilateral Cleft Lip and Palate Children Versus Normal Children .
The aim of the present study is to determine the effect of surgically repaired UCLP on dental arch dimensions and the need for orthodontic intervention in comparison with other healthy children , the presence of dental anomalies…
- Trial name
- NCT04791813
- Testing
- Alginate impressions , Photographic data and panoramic radiographs .
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Lip
Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment
Alveolar bone grafting (ABG) is an essential part of the surgical management of cleft lip and palate patients. This procedure could obliterate oronasal fistula, stabilize dental arch, offer bone matrix for adjacent teeth…
- Trial name
- NCT02454998
- Testing
- orthodontic treatment
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Cleft Lip and Palate
Progression of Grafted Bone Density in Cleft Alveolus
The patients with unilateral and bilateral cleft lip and palate received alveolar bone graft surgery. Two time points of cone beam CT were taken for all the patients: post-operative 6 months, and post-operative 2 years.
- Trial name
- CDAABG (NCT04987190)
- Testing
- alveolar bone graft
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Unilateral Cleft Lip and Palate
Effect of Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients
This study includes Three Dimensional Evaluation of Maxillary Arch Changes After Using Two Different Construction Techniques of Nasoalveolar Molding Devices in Unilateral Cleft Lip and Palate Patients (Randomized Controlled…
- Trial name
- NCT05837780
- Testing
- Nasoalveolar molding device
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Cleft Lip and Palate
Effect of Novel Nasoalveolar Molding Techniques on Parents' Satisfaction and Short Term Treatment Outcomes in Unilateral Cleft Lip and Palate Infants: A Randomized Controlled Trial
The aim of this trial is to figure out the efficiency of modified Grayson NAM on parents' satisfaction, nasal esthetics, interlabial gap and maxillary arch changes.
- Trial name
- NCT02845193
- Testing
- Modified Nasoalveolar molding, Taping, CAD/NAM
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cairo University