Clinical trials: Type1diabetes
Covid19, type1diabetes
Covid-19 Infection and New Onset Type 1 Diabetes
Although recognized as an autoimmune disease the etiology of type 1 diabetes remains unknown. Virus infections has been suggested as a possible agent triggering the autoimmune reaction finally resulting in beta-cell destruction…
- Trial name
- NCT04623697
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
type1diabetes
Empagliflozin in Adolescent Diabetes
Empagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2), reduces post-prandial glucose levels in adults with both type 2 and type 1 diabetes and importantly reduces both cardiovascular and renal complications…
- Trial name
- NCT04917692
- Testing
- Empagliflozin
- Where
- United States
- Sponsor
- Ohio State University
Type1diabetes, Hypoglycemia
Introducing CGM at Type 1 Diabetes Diagnosis
Diabetes technology is changing and has quickly become an integral part of diabetes care and management. The study team plans to study the effects of introducing technology to newly diagnosed type 1 diabetes patients.
- Trial name
- NCT03736083
- Testing
- Freestyle Libre Blood Glucose Monitor
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Type 1 Diabetes, Hypoglycemia
Neuronostatin - a Glucagonotropic Agent in Humans?
With the present study the investigators wish to delineate the effects of neuronostatin-13 (NST) on glucose-dependent glucagon secretion in humans.
- Conditions
- Type 1 Diabetes, Hypoglycemia, Type1diabetes
- Trial name
- NSTCLAMP (NCT06143267)
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Type1diabetes
Can Continuous Glucose Measurements Help Diabetic Patients Treated With an Implantated Pump?
During this study, we propose to assess the utility of Continuous Glucose Measurements (CGM) in a group of Type 1 diabetic patients treated with an implanted insulin pump.
- Trial name
- CGMIP (NCT03048227)
- Testing
- Continuous Glucose Measurement (CGM)
- Where
- 10 sites in France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Montpellier
type1diabetes, Type2 Diabetes
Efficacy and Safety of Recombinant Human Insulin Patch ZJSRM2021
The aim of this study is to investigate the efficacy，safety， and tolerability of the recombinant human insulin patch ZJSRM2021 in healthy subjects, type 1diabetes mellitus and type 2diabetes mellitus patients
- Trial name
- NCT05089942
- Testing
- Recombinant Human Insulin Patch ZJSRM2021
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial People's Hospital
Type1diabetes
Assay for the Pancreatic Polypeptide: an Help for Clinical Practice Guidelines in Classification of the Diabetes
The purpose of this study is to evaluate global endocrine function within type 1 and type 3c diabetic patients, helping pancreatic polypeptide measurement.
- Trial name
- DIAPP (NCT03396146)
- Testing
- 12 ml total blood tubes volume, Fecal sample
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Type1diabetes
Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet
Despite major technological advances, management of type one diabetes mellitus (T1D) remains suboptimal, putting millions of people at risk for immediate and long-term complications.
- Trial name
- NCT03710928
- Testing
- very low carbohydrate diet, standard carbohydrate diet
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Boston Children's Hospital
Type1diabetes
Advanced Glycation Products and Vascular Complications in Type 1 Diabetes
DIABAGE (Diabetes Advanced Glycation End products) study was conducted between 2015 and 2017. It included 196 type 1 diabetic patients with more than 10 years of diabetes.
- Trial name
- DIABAGE (NCT06458088)
- Where
- France
- Volunteers
- 196 people
- Sponsor
- CHU de Reims
Type1diabetes, Covid19
Covid-19 Pandemic: Patients' Experience in T1D
Given the current situation with COVID-19 declared pandemic on March 11, 2020 and the requirement for physical distancing and to limit social interactions, and for some, to quarantine, the investigators will survey patients…
- Trial name
- NCT04384471
- Testing
- Online survey
- Where
- Canada
- Volunteers
- 384 people
- Sponsor
- McGill University
Type1diabetes
Safety of Closed-loop Hybrid Insulin Administration During Ramadan Fasting in People Living With Type 1 Diabetes
Fasting in Ramadan is not recommended for people with type 1 diabetes. The main risk associated with fasting is dysglycemia (hypoglycemia, hyperglycemia, diabetic ketosis) and dehydration.
- Trial name
- RAMDAM (NCT05747352)
- Testing
- closed-loop hybrid insulin administration
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Centre Hospitalier Sud Francilien
Type1diabetes, Psychology Functional Behavior
A Trial of Diabetes-educated Psychologist to Improve HbA1c and Reduce Diabetes-related Distress
Type 1 diabetes is associated with a significant increase in mortality, cardiovascular disease, injuries on eyes and kidneys. These risks are largely dependent on glycemic control.
- Trial name
- NCT03753997
- Testing
- Treatment by a diabetes educated psychologist
- Where
- Sweden
- Volunteers
- 142 people
- Sponsor
- Vastra Gotaland Region
Type1diabetes
Gluten and Amylase Trypsin Inhibitors (ATI) Free Diet
Siblings of those with type 1 diabetes are at an increased risk of developing the disease themselves. Through prior research, the investigators have found that siblings as well as those with type 1 diabetes have a general level…
- Trial name
- NCT03443180
- Testing
- Gluten and Amylase Trypsin Inhibitors (ATI)-free diet
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
type1diabetes, CGM
Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System
The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference venous plasma sample measurements.
- Conditions
- type1diabetes, CGM, T1D
- Trial name
- NCT07745244
- Testing
- GS3 CGM
- Where
- China
- Volunteers
- 36 people
- Sponsor
- SiBionics, Co, Ltd
Type1diabetes, Diabetes Mellitus, Type 1
Genetics Of Autoimmunity In Type I Diabetes
The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 diabetes.
- Conditions
- Type1diabetes, Diabetes Mellitus, Type 1, Type1 Diabetes Mellitus, Diabetes Mellitus
- Trial name
- NCT03648918
- Testing
- Blood Collection
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Type1diabetes
Comparative Study Between Two Models of a Non-invasive Glucose Monitoring Device
This clinical study has been launched to compare the performances of two models of a non-invasive glucose monitoring device.
- Trial name
- NCT03530644
- Testing
- WM3.4NR, P0.1
- Where
- Denmark
- Volunteers
- 3 people
- Sponsor
- RSP Systems A/S
Type1diabetes, Obesity
Tirzepatide Use in People With Obesity and Type 1 Diabetes
Tirzepatide, a gut hormone-based medication, has shown promising results in treating obesity, with ~22% weight loss and mild side effects.
- Trial name
- NCT07096908
- Testing
- Tirzepatide
- Where
- Kuwait
- Volunteers
- 60 people
- Sponsor
- Dasman Diabetes Institute
Type1diabetes, Depressive Symptoms
Type 1 Diabetes and Depression: Role of Brain Glutamate
The goal of this study is to examine the effect of chronic and acute hyperglycemia in type 1 diabetes mellitus (T1DM) on brain glutamate levels using magnetic resonance spectroscopy (MRS), and associations of brain glutamate with…
- Conditions
- Type1diabetes, Depressive Symptoms, Major Depressive Disorder
- Trial name
- NCT05355285
- Testing
- Glucose Clamp
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Lipodystrophy Acquired, Type1diabetes
Cyclophosphamide in the Treatment of Associated Acquired Lipodystrophy Syndrome With Type 1 Diabetes
This study evaluates the change of insulin resistance and glucose metabolism of patients with panniculitis associated acquired lipodystrophy syndrome and type 1 diabetes with the treatment of cyclophosphamide.
- Trial name
- NCT03936829
- Testing
- Cyclophosphamide
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Fudan University
Type1diabetes, Therapeutic Play
The Effect of Therapeutic Play on Anxiety and Fear Levels in Children With Diabetes
The study will be conducted using a randomized controlled method. Children with type 1 diabetes who are admitted to the Pediatric Endocrinology Service will be divided into two groups by randomization method.
- Conditions
- Type1diabetes, Therapeutic Play, Fear State, Anxiety State
- Trial name
- NCT06418269
- Testing
- Therapeutic Play
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa