Clinical trials: Transgender
Contraception
A Novel IUD Insertion Technique
A previous trial performed by our research team, in order to reduce the pain associated with intrauterine device insertion, compared the novel technique of IUD insertion under the guidance of the trans-abdominal sonography to the…
- Trial name
- NCT02582268
- Testing
- intrauterine device TCu 380A, Trans-abdominal sonography
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Dry and Sensitive Skin
Validation of Skin Instrumentation to Detect Ceramide-Driven Lipid Replenishment - Assessing Skin Glow, Hydration, Trans Epidermal Water Loss, Skin Surface Assessment, Sebum and Least-Reflection Factor.
This is a single-center, open-label, split-face, site-randomized validation study, NB250045-NB-V designed to establish and confirm the reliability, reproducibility, and sensitivity of various skin measurement methods.
- Trial name
- NCT07423325
- Testing
- Marketed Product - CeraVe Moisturizer
- Where
- India
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Glaucoma, Glaucoma Following Surgery
Anterior-segment OCT (AS-OCT) and Intraoperative OCT (iOCT) for Trans- Conjunctival Needle Revision (TCNR)
Trabeculectomy is a very important and commonly performed glaucoma operation. It allows fluid from inside the eye to exit into a space called a bleb located on the surface of the eye under the upper eyelid.
- Trial name
- NCT05790408
- Testing
- Digital microscope integrated with intraoperative OCT (Zeiss Artevo 800, Carl Zeiss Meditec AG), Spectralis Anterior-segment OCT (AS-OCT) (Heidelberg Engineering)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northwestern University
Transgender, Renal Function
Renal Effects of Hormones/Biomarkers in Transgender PrEP Recipients
Will use a subset of the main study cohort of transgender or non-binary individuals to evaluate the relationships between self-reported exogenous hormone use, endogenous hormone values, renal biomarkers, drug levels and directly…
- Conditions
- Transgender, Renal Function, Hormone Replacement Therapy
- Trial name
- NCT04742816
- Testing
- IHX-CL measurements, Iohexol
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of California, San Diego
Prostate Cancer
Robotic-arm Assisted Ga-68 PSMA PET/CT Guided Transgluteal Prostate Biopsy
Gallium-68 prostate-specific-membrane-antigen (Ga-68 PSMA) PET/CT is being used in Prostate cancer imaging. In the present study, we aimed to evaluate the efficacy and safety of robotic arm-assisted Ga-68 PSMA PET/CT-guided…
- Trial name
- NCT05022576
- Testing
- Robotic arm assisted PSMA PET/CT guided prostate biopsy
- Where
- India
- Volunteers
- 78 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Obesity, Insulin Resistance
Resveratrol and the Metabolic Syndrome
Metabolic syndrome is a serious health condition that affects about 35 percent of adults and places them at higher risk of cardiovascular disease, diabetes, stroke and diseases related to fatty buildups in artery walls.
- Conditions
- Obesity, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT01714102
- Testing
- Resveratrol
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Transgenderism, HIV Infections
Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions
The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and…
- Trial name
- NCT05666102
- Testing
- Transgender men's perspectives on HIV risk and HIV prevention interventions
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Adenoid Cystic Carcinoma of the Head and Neck
All-trans Retinoic Acid (ATRA) in the Treatment of Recurrent/Metastatic Adenoid Cystic Carcinoma of the Head and Neck
This is a prospective, open-label, randomized controlled clinical intervention study to evaluate the efficacy and safety of all-trans retinoic acid (ATRA) in treating patients with recurrent metastatic adenoid cystic carcinoma of…
- Trial name
- Aplus (NCT04433169)
- Testing
- All-trans Retinoic Acid, VEGFR inhibitor, Chemotherapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Endothelial Dysfunction
Effects of Trans-Resveratrol in Endothelial Function in Hypertensive Patients
Arterial Hypertension (HBP) has a high prevalence and low rates of control, is considered a major modifiable risk factors and one of the most important public health problems.
- Trial name
- NCT02616822
- Testing
- Trans-resveratrol
- Volunteers
- 24 people
- Sponsor
- Hospital Universitario Pedro Ernesto
Aging
VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements
This study aims to assess the safety and efficacy of study drugs and supplements on clinical (structural and functional) signs of aging and to explore/identify other possible biological measures of aging.
- Trial name
- NCT04994561
- Testing
- Study Drugs and Nutritional Supplements
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vitality in Aging Research Group, Inc.
Hepatocellular Carcinoma
Hypoxic Changes in Hepatocellular Carcinoma (HCC) Following Trans Arterial Chemo Embolization and Stereotactic Radiation: Fluorine18 (18F) Fluoromisonidazole (FMISO) Imaging
[18F] FMISO Positron Emission Tomography (PET) to determine hypoxia in patients with HCC treated with TACE.
- Trial name
- NCT03303469
- Testing
- FMISO
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Alabama at Birmingham
Urinary Bladder Cancer, Urinary Bladder Neoplasm
Neutrophils to Lymphocytes Ratio in Predicting the Response to BCG in Non-muscle Invasive Bladder Cancer
There is a relation between inflammatory cells and the prognosis of tumors (cancer colon, renal, liver, and urinary bladder). In this study, the investigators will link the Neutrophils to Lymphocytes ratio to the response to…
- Conditions
- Urinary Bladder Cancer, Urinary Bladder Neoplasm, BCG, Trans Urethral Resection of a Bladder Tumor
- Trial name
- NCT05946369
- Testing
- Neutrophil to lymphocyte ratio
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Ain Shams University
Operative Time, Grip Strength
Safety Study of Surgical Technique to Treat Acute Dorsal Trans-Scaphoid Perilunate Dislocations
The purpose of this study is to determine a surgical technique is effective in the treatment of acute dorsal trans-scaphoid perilunate dislocations.
- Conditions
- Operative Time, Grip Strength, Pain, Functional Status
- Trial name
- ADTPD (NCT00738127)
- Testing
- Open reduction and internal fixation
- Where
- China
- Volunteers
- 801 people
- Sponsor
- The Second Hospital of Qinhuangdao
Transgenderism, Catheter Related Complication
Safe Access for Bladder Entry in Transgender Men Following Penile Reconstruction
Inserting a urinary catheter in transgender men following penile reconstruction is difficult and usually requires specialist input.
- Trial name
- SAFE (NCT04454970)
- Testing
- Urethrotech Urethral catheterisation device (UCD), Bardia Aquafil long term catheter
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University College, London
Hernia, Inguinal
Changing the Innate Consensus About Mesh Fixation in Trans-abdominal Preperitoneal Laparoscopic Inguinal Hernioplasty in Adults: Short and Long Term Outcome. Randomized Controlled Clinical Trial
Introduction: Inguinal hernioplasty is the standard treatment for inguinal hernia. Mesh fixation is used to keep mesh in place for which various mesh fixation techniques have been used in laparoscopic inguinal hernia repair, but…
- Trial name
- NCT04272424
- Testing
- laparoscopic mesh fixation
- Volunteers
- 3 people
- Sponsor
- Zagazig University
HIV, STIs
The South-East Asian Transgender Health Cohort
This is a prospective observational cohort study that will enroll 300 HIV-negative transgender people and 150 transgender people living with HIV from 4 community health centers in Thailand, Vietnam, and the Philippines.
- Conditions
- HIV, STIs, HCV
- Trial name
- SEATrans (NCT05454579)
- Where
- 5 sites in Philippines, Thailand and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Maxillary Sinus Disease
Evaluation of Bone Height Gain Following Trans-crestal Sinus Floor Elevation
Missing teeth usually result in functional and cosmetic deficits. Traditionally, they have been restored with dentures or fixed bridges.
- Trial name
- NCT05411510
- Testing
- Densah bur
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Ahmed Mohamed Said Rozeik
Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL
This is a Phase II single-center open label trial of the combination of ATRA and pembrolizumab treatment in patients with histologically proven, relapsed or refractory Hodgkin Lymphoma or B-Non-Hodgkin-lymphoma.
- Conditions
- Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma
- Trial name
- NCT06484920
- Testing
- ATRA, Pembrolizumab
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Rita Assi
Gender Dysphoria, Gender Identity Disorder
TransCare - Genital Surgery for Trans Women in Centralized vs. Decentralized Health Care Delivery Settings
Trans (i.e., transgender, transsexual) individuals experience a gender that does not match their sex assigned at birth (Gender Incongruence), which can lead to distress called gender dysphoria (formerly known as transsexualism).
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT03872648
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pregnancy (Unwanted), Sexually Transmitted Disease (STD)
#TranscendentHealth: A Text Messaging Pregnancy Prevention Program for Transgender Boys
Transgender and gender-diverse young people who were assigned female at birth (AFAB), including transgender boys, nonbinary youth, and others, face real sexual health disparities.
- Conditions
- Pregnancy (Unwanted), Sexually Transmitted Disease (STD), HIV Infection, Sexual Behavior
- Trial name
- THPP (NCT07681908)
- Testing
- #TranscendentHealth, Universal Sexual Health Program
- Where
- United States
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Center for Innovative Public Health Research