Clinical trials: Tracheostomy Weaning
Weaning From Mechanical Ventilation, Tracheostomy Weaning
Physiological Effect High-flow Tracheal Oxygen on Viscosity of Airway Mucus and Respiratory Effort in Patients Weaning From Invasive Mechanical Ventilation
Rationale: Tracheostomized patients weaning from mechanical ventilation are at risk for dryness of airway mucosa and sputum accumulation during disconnection from mechanical ventilation.
- Conditions
- Weaning From Mechanical Ventilation, Tracheostomy Weaning, Respiratory Failure
- Trial name
- PIONEER (NCT06776939)
- Testing
- Oxygen therapy
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Henrik Endeman
Prolonged Mechanical Ventilation, Ventilator Weaning
Standardized Tracheostomy Weaning Protocol for Prolonged Mechanical Ventilation
This study evaluated the feasibility and clinical outcomes of a standardized weaning protocol for tracheostomized patients requiring prolonged mechanical ventilation.
- Conditions
- Prolonged Mechanical Ventilation, Ventilator Weaning, Tracheostomy
- Trial name
- NCT06642714
- Testing
- Standardized Stepwise Weaning Protocol
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Capital Medical University
Tracheostomy Weaning, Tracheostomy Decannulation
WEANING FROM TRACHEOSTOMY
Tracheostomy is a very common surgical procedure performed in critically ill patients on invasive mechanical ventilation, and usually performed in difficult-to-wean patients and whn prolonged mechanical ventilation is required.
- Trial name
- NCT05271786
- Testing
- Decannulation
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- University of Milan
Tracheostomy, Cough
Objective Evaluation of Cough Effort in Tracheotomized Patients (LOST Study)
This study aims to evaluate how well tracheotomized patients can cough before and after their tracheostomy tube is removed. Cough strength is measured using two different tools-Peak Flow and Lorio.
- Conditions
- Tracheostomy, Cough, Weaning, Respiratory Function Tests
- Trial name
- NCT07061561
- Testing
- Peak Expiratory Flow Measurement Using Peak Flow Meter and Lorio Device
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Tracheostomy, ICU
Determinants of Successful Decannulation in Difficult-to-wean Patients
The factors of success of decannulation are not well known in the literature and the decision to decannulate is mainly based on clinical judgment.
- Conditions
- Tracheostomy, ICU, Weaning Failure
- Trial name
- DESCATRON (NCT04841889)
- Testing
- Associated factors with decannulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Forcilles
Tracheostomy Weaning
Decannulation of Tracheostomy Cannula Based on Suctioning Frequency and High-flow Oxygen Protocol in the Intensive Care Unit
In the DECAP-ICU trial, the investigators will be focusing on the impact of a new weaning tracheostomy technique based on suctioning frequency compared to the standard practice of capping tolerance.
- Trial name
- DECAP-ICU (NCT05778682)
- Testing
- Suctioning based protocol, Usual Care
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Université de Sherbrooke
Invasive Mechanical Ventilation, Critical Illness
Mechanical Ventilation Discontinuation Practices
Background: The requirement for ventilator support is a defining feature of critical illness. Weaning is the process during which the work of breathing is transferred from the ventilator back to the patient.
- Conditions
- Invasive Mechanical Ventilation, Critical Illness, Spontaneous Breathing Trial, Weaning Invasive Mechanical Ventilation
- Trial name
- IOS (NCT03955874)
- Where
- 14 sites in United States, Canada
- Volunteers
- 1,868 people
- Sponsor
- Unity Health Toronto
Weaning, Tracheostomy
Does Deflating the Tracheal Cuff Shorten Weaning Time?
The purpose of this study is to determine whether deflating the tracheal cuff in tracheostomized patients, during disconnections from ventilatory support along the weaning phase shortens the weaning time.
- Trial name
- NCT00956540
- Testing
- Deflating tracheal cuff, Deflating tracheal cuff 2
- Where
- Spain
- Volunteers
- 195 people
- Sponsor
- Hospital Virgen de la Salud