Clinical trials: Thyroid Nodule
Multimoda Lultasound, Thyroid Cancer
Multimodality US Based on Angio Planewave Ultrasensitive Imaging and Shear Wave Elastography to Evaluate the Malignancy Risk Value of Thyroid Nodules
The goal of this clinical trial is to explore the value of a multimodal ultrasound model based on Angio Planewave Ultrasensitive Imaging, Shear Wave Elastography and grayscale ultrasound in the differential diagnosis of benign…
- Conditions
- Multimoda Lultasound, Thyroid Cancer, Microvascular Classification
- Trial name
- NCT06530771
- Testing
- ultrasound
- Where
- China
- Volunteers
- 720 people
- Sponsor
- Fifth Affiliated Hospital, Sun Yat-Sen University
Thyroid Abnormalities
Thyroid Abnormalities Associated With Exposure to Atmospheric Emissions of Radioactive Iodine
Background: An inadequate filtering system at the Mayak nuclear weapons production facility in Ozyorsk, Russia, allowed the release of various radioactive materials, particularly I-131 (radioactive iodine) into the city's…
- Trial name
- NCT00342693
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Cancer Institute (NCI)
Thyroid Nodule
Application of Ultrasonic Gray-scale Ratio in Differentiating Benign From Malignant Thyroid Nodules.
According to the grades of echogenicity to evulated thyroid nodules is a subjective process and is thus influenced by the observer's judgement.
- Trial name
- NCT03700762
- Testing
- ultrasound gray-scale ratio
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Hangzhou
Thyroid Nodule
Protein Classifier for Thyroid Indeterminate Nodules
In multi-center, prospective, double-blind cohorts, PCT-DIA/MS protein classifier supported by artificial neural networks will be validated to classify thyroid indeterminate nodules.
- Trial name
- NCT04477798
- Testing
- PCT-DIA/MS
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Luo Dingcun
Thyroid Nodule
Surgical Versus Non Surgical Management of Thyroid Nodule
To compare between surgical (hemi thyroidectomy and total thyroidectomy) and non-surgical (medical, ethanol injection,thermal ablation and laser photo coagulation) management of simple thyroid nodule regarding: Outcome of every…
- Trial name
- NCT04580199
- Testing
- thyroidectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahmoud Fahd
Thyroid Nodule, Thyroid Neoplasm
Molecular Classifier for the Fine Needle-based Assessment of Malignancy Risk in Thyroid Nodules
This study evaluates the usefulness of molecular classifier to aid the diagnosis of malignancy in the material obtained by fine-needle aspiration biopsy (FNAB) of thyroid nodule.
- Conditions
- Thyroid Nodule, Thyroid Neoplasm, Thyroid Cancer
- Trial name
- ThyroPred-1 (NCT03392402)
- Where
- Poland
- Volunteers
- 599 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Thyroid Neoplasm, Goiter
Total Thyroidectomy With Harmonic Scalpel®
Harmonic scalpel is a new surgical instrument. Its use has been recommended in patients submitted to total thyroidectomy. Few randomized controlled trials has been published.
- Conditions
- Thyroid Neoplasm, Goiter, Thyroid Nodule
- Trial name
- NCT00385983
- Testing
- Harmonic Scalpel
- Where
- 9 sites in Brazil
- Volunteers
- 280 people
- Sponsor
- Brazilian Society of Head and Neck Surgery
Thyroid Gland Carcinoma
Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid Nodules
This clinical trial evaluates deoxyribonucleic acid (DNA) methylation signatures in diagnosing and managing thyroid nodules. The purpose of this research is to develop a new test for thyroid cancer.
- Trial name
- NCT05229341
- Testing
- Diagnostic Procedure, Electronic Health Record Review, Needle Biopsy
- Where
- United States
- Volunteers
- 1,450 people
- Sponsor
- City of Hope Medical Center
Thyroid Neoplasm
Validation of the Diagnostic Accuracy of the Electronic Nose in the Detection of Thyroid Cancer
Patients with a suspected thyroid nodule face an invasive and patient unfriendly diagnostic work-up to determine the risk of malignancy.
- Trial name
- NCT04883294
- Testing
- Electronic Nose
- Volunteers
- 1,500 people
- Sponsor
- Maastricht University Medical Center
Thyroid Nodule
Accuracy of FNAC in Diagnosis of Thyroid Nodules
Detection of degree of accuracy of FNAC in diagnosis of thyroid nodules
- Trial name
- NCT06782828
- Testing
- observe results of FNAC
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Neoplasms, Thyroid Nodules
Is the Routine Pressure Dressing After Thyroidectomy Necessary?
Thyroidectomy is an operation that is commonly performed. After an operation a pressure dressing by Hypafix is usually used due to the belief that it will help to reduce complications such as post-operative bleeding or haematoma.
- Conditions
- Thyroid Neoplasms, Thyroid Nodules, Graves Disease, Goiter
- Trial name
- NCT00400465
- Testing
- Normal dressing, Pressure dressing
- Where
- Thailand
- Volunteers
- 116 people
- Sponsor
- Khon Kaen University
Thyroid Nodule, Thyroid Cancer
The Safety and Feasibility of Radiofrequency Ablation to Treat Low-risk Thyroid Cancer
The goal of this clinical trial is to test radiofrequency ablation (RFA) in thyroid cancers ≤2 cm in diameter. The main question it aims to answer is: What is the feasibility of RFA use for low-risk thyroid cancers (≤2 cm)?…
- Trial name
- NCT06929650
- Testing
- Radiofrequency ablation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Tumor
Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors
This is a study to assess the combination of PXD101 and 5-Fluorouracil (5-FU)in patients with advanced solid tumors. The primary goal of the study is to understand the safety, anti-tumor activity, and how the study drug behaves…
- Trial name
- NCT00413322
- Testing
- belinostat, 5-Fluorouracil (5-FU)
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Valerio Therapeutics
Thyroid Neoplasms
Accuracy of FDG-PET Scanning to Diagnose Malignant Thyroid Nodules
The main purpose of this study is to see how well FDG-PET scans can determine the malignancy of thyroid nodules that have already been tested (and come back positive) by fine needle aspiration.
- Trial name
- NCT00537797
- Testing
- FDG-PET Scan
- Where
- 3 sites in United States
- Volunteers
- 84 people
- Sponsor
- Washington University School of Medicine
Thyroid Nodules
Realtime-Elastography (RTE) and Thyroid Nodules
The study is an open, prospective multicenter study. According to the statistical sample size calculation 593 patients with thyroid nodules ≥ 5mm in size will be included in the study.
- Trial name
- NCT01609946
- Testing
- Realtime-Elastography, linear ultrasound probe, Hitachi EUB-900, Japan, Cytology (FNAB) or Surgery
- Where
- 10 sites in Germany
- Volunteers
- 602 people
- Sponsor
- Johannes Vermehren
Benign Thyroid Nodules
Study of the Feasibility of Radiofrequency Ablation of Benign Thyroid Nodules
The purpose of the present protocol is to evaluate the response rate to treatment of these symptomatic benign nodules with radiofrequency as an alternative to surgical treatment.
- Trial name
- TRAF (NCT03646383)
- Testing
- Radiofrequency ablation
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Toulouse
Thyroid Cancer, Thyroid Nodule
Surgical Competency for Robot-Assisted Thyroidectomy: Construction and Validation of a Robotic Thyroidectomy Assessment Score (RTAS)
To develop and validate a structured scoring tool (robotic thyroidectomy assessment score, RTAS) for assessing and quantifying surgical performance in robotic thyroidectomy (RT).
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Diseases, Thyroid Cancer, Papillary
- Trial name
- NCT06730321
- Testing
- Observations on clinicopathological factors influencing the assessment score of surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai 6th People's Hospital
Thyroid Nodules, Pulsed Field Ablation
Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules
To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.
- Trial name
- NCT07226804
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Nodule
Clinical Study of Ultrasonic Artificial Intelligence and Fine Needle Aspiration in Qualitative Diagnosis of Thyroid Nodules
To study the value of thyroid artificial intelligence diagnosis system and fine needle puncture in the diagnosis of benign and malignant thyroid nodules, so as to provide evidence-based medical evidence for the diagnosis of…
- Trial name
- NCT05407506
- Testing
- THYROID AI
- Volunteers
- 1,000 people
- Sponsor
- Luo Dingcun