Clinical trials: Thyroid Dysfunction, active
Thyroid Eye Disease, Graves Ophthalmopathy
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam lid/orbital edema, or lid/orbital erythema recommended for treatment…
- Conditions
- Thyroid Eye Disease, Graves Ophthalmopathy, Graves Disease
- Trial name
- Teprotumumab (NCT06275373)
- Testing
- Teprotumumab Injection [Tepezza]
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Rheumatoid Arthritis, Subclinical Hypothyroidism
Subclinical Hypothyroidism and Disease Activity in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that causes persistent joint inflammation and damage. Thyroid disorders, particularly subclinical hypothyroidism, are common co-existing conditions in…
- Conditions
- Rheumatoid Arthritis, Subclinical Hypothyroidism, Thyroid Dysfunction
- Trial name
- NCT07793786
- Volunteers
- 150 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus (T2DM), Thyroid Dysfunction
Relationship Between Thyroid Dysfunction and Diabetes
Evaluate the expression of glycemic parameters, lipid profile, and thyroid hormones in patients with type 2 diabetes mellitus in upper egypt.
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Thyroid Dysfunction, Metabolic Syndrome, Upper Egypt Patients
- Trial name
- NCT07099937
- Testing
- Observational cross-sectional study with no intervention.
- Volunteers
- 120 people
- Sponsor
- Assiut University
Geriatric Diseases
Thyroid Dysfunction in Elderly
Thyroid dysfunction in elderly
- Trial name
- Thyroid dysfun (NCT07606560)
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Assiut University
Liver Dysfunction, Thyroid
DEscripitive Patient Analysis to Enable Risk-based Quality Improvement Measures in a lArge iNternal mediCIne grouP Practice
Background: Clinical trials often include patients from large hospitals or university clinics. Information on patients cared for at offices from statutory health insurance-accredited physicians represent evidence gaps.
- Conditions
- Liver Dysfunction, Thyroid, Atherosclerosis, Heart Failure
- Trial name
- EMANCIPATE (NCT06178302)
- Volunteers
- 1,000 people
- Sponsor
- Imed19
Thyroid Dysfunction, Hemodialysis
Evaluation of Thyroid Function, Lipid Profile, and Uric Acid Levels in Hemodialysis Patients
This observational study evaluates the prevalence and relationships of thyroid dysfunction, lipid abnormalities, and elevated uric acid levels in adult patients undergoing maintenance hemodialysis at Assiut University Hospital.
- Conditions
- Thyroid Dysfunction, Hemodialysis, Elevated Uric Acid
- Trial name
- NCT07157267
- Volunteers
- 100 people
- Sponsor
- Assiut University
Metabolic Dysfunction-Associated Steatotic Liver Disease, Hypothyroidism
Hypothyroidism and Liver Fibrosis Severity in MASLD
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide, characterized by excess fat accumulation in the liver associated with metabolic risk factors such as obesity and…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Hypothyroidism, Liver Cirrhosis, Non-Alcoholic Fatty Liver Disease
- Trial name
- NCT07793279
- Volunteers
- 85 people
- Sponsor
- Assiut University
Ocular Motility Disorders, Strabismus
Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM)
This prospective, multicenter, multinational observational study evaluates the clinical validity of an AI-based quantitative eye movement analysis system (Glandy EOM) that analyzes smartphone-recorded 9-gaze videos.
- Conditions
- Ocular Motility Disorders, Strabismus, Extraocular Muscle Dysfunction, Thyroid Eye Disease
- Trial name
- GLANDY-EOM-VAL (NCT07623837)
- Testing
- Glandy EOM (AI-based quantitative eye movement analysis software)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- THYROSCOPE INC.
High-risk Pregnancy
Association of Maternal Thyroid Function and Anxiety With Fetal Cardiotocography Parameters in High-Risk Pregnancies
This prospective observational study aims to investigate the association between maternal thyroid function, maternal anxiety levels, and fetal cardiotocography parameters in high-risk pregnancies.
- Trial name
- NCT07774949
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul Training and Research Hospital
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Thyroid Dysfunction
Prevalence and Prognostic Effects of Thyroid Abnormalities in Patients With Acute Coronary Syndrome.
The goal of this observational study is knowledge of Prevalence of throid abnormalities in patients with acute coronary syndrome And prognostic effects of thyroid abnormalities in patients with acute coronary syndrome as early…
- Trial name
- NCT06579014
- Volunteers
- 129 people
- Sponsor
- Assiut University
Thyroid Disease
Effect of Nutrition Education on the Quality of Life, Chronic Disease Adaptation in Patients With Thyroid Dysfunction
This thesis study is designed to examine the effects of nutrition education provided to individuals with thyroid dysfunction on their quality of life and adaptation to the disease.
- Trial name
- NCT07027579
- Testing
- Nutrineal
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Çanakkale Onsekiz Mart University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Thyroid Disease
Impact Of Thyroid Dysfunction on Liver Function Tests
This study aims to evaluate the effect of thyroid dysfunction on liver function tests.
- Trial name
- NCT07354048
- Testing
- Control group, Patients with hypothyroidism or hyperthyroidism that are controlled on treatment, Patients with hypothyroidism or hyperthyroidism that are not controlled on treatment
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Thyroid Disorders Complicating Pregnancy, Maternal Depression in Pregnancy, Unspecified Trimester
Thyroid-Stimulating Hormone Levels in Pregnancy and Their Association With Depression, Anxiety, and Sexual Function
This prospective, single-center, observational cross-sectional study aims to evaluate the relationship between thyroid-stimulating hormone (TSH) levels and psychological as well as sexual health outcomes during pregnancy.
- Conditions
- Thyroid Disorders Complicating Pregnancy, Maternal Depression in Pregnancy, Unspecified Trimester, Anxiety Disorder, Unspecified, Sexual Dysfunction, Unspecified
- Trial name
- TSH-MIND (NCT07272213)
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
GI Disorders
Esophageal Motility and Gastric Emptying Disorders Among Different Thyroid Dysfunction
Detect prevalence of different gastroparesis symptoms among different thyroid disorders Effect of thyroid disorders either hypothyroidism, hyperthyroidism and subclinical disorders in upper gastro motility
- Trial name
- NCT07069816
- Testing
- Scintigraphy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Dysfunction, Metabolic Dysfunction-Associated Fatty Liver Disease
Thyroid Dysfunction and Its Association With Metabolic Dysfunction-Associated Fatty Liver Disease
This study aims to evaluate the prevalence of thyroid dysfunction and its association with metabolic dysfunction-associated fatty liver disease.
- Trial name
- NCT06739330
- Testing
- Fibroscan
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tanta University
Thyroid Dysfunction, Immune Thrombocytopenic Purpura
Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura Patients
Study of relation between thyroid dysfunction and immune thrombocytopenic purpura patients and if there is relation between them
- Trial name
- NCT07900334
- Testing
- Laboratory tests TSH, FT3, FT4 ,anti thyroglobulin antibodies, Anti -TPO antibodies
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Thyroid; Functional Disturbance, Hypothyroidism
A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients
Hypothyroidism, defined by elevated thyrotropin (TSH) levels, is a common endocrine complication in chronic kidney disease patients, and prior evidence shows that higher TSH levels, even within the normal laboratory range, are…
- Conditions
- Thyroid; Functional Disturbance, Hypothyroidism, Hemodialysis
- Trial name
- THYROID-HD (NCT03977207)
- Testing
- Levothyroxine Sodium
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of California, Irvine
Overt, Sub-clinical
Association Between Overt and Sub-clinical Primary Hypothyroidism and Metabolic Dysfunction-Associated Steatoic Liver Disease in Non-Diabetic Patients
This study aims to estimate the prevalence of Metabolic dysfunction - associated Steatoic liver disease (MASLD) among adults with primary hypothyroidism (overt or sub-clinical 1ry hypothyroidism) and prevalence of MASLD in…
- Conditions
- Overt, Sub-clinical, Primary Hypothyroidism, Metabolic Dysfunction-Associated Steatoic Liver Disease
- Trial name
- NCT07603817
- Testing
- FibroScan, Thyroid Function Assessment
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University