Clinical trials: Thrombolytic Therapy
Pulmonary Embolism Subacute Massive, Thrombolytic Therapy
Effect of Thrombolysis on 30-day Mortality in Intermediate High Risk Pulmonary Patients With Low Bleeding Risk
The aim of investigators was to study the effect and safety of Thrombolysis in Intermediate high risk pulmonary embolism patients with low bleeding risk as regards Mortality and bleeding events.
- Trial name
- NCT07374978
- Testing
- Thrombolytic therapy for the study group in the form of streptokinase or recombinant tissue plasminogen activator, Unfractionated Heparin IV
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Stroke, Ischemic, Thrombectomy
Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot.
- Conditions
- Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy, Brain Ischemia
- Trial name
- NCT07069452
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier de Gonesse
Stroke, Ischemic Attack, Transient
Impact of Door-to-Needle Time on Stroke Outcomes at Gonesse Hospital
This study looks at how quickly stroke patients receive treatment after arriving at Gonesse Hospital and whether this affects their recovery.
- Conditions
- Stroke, Ischemic Attack, Transient, Cerebral Infarction, Thrombolytic Therapy
- Trial name
- NCT07018167
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Hospitalier de Gonesse
Hemodialysis, Thrombolytic Therapy
Comparison of Standard Versus High Dose Urokinase for Dysfunctional Tunneled Dialysis Catheters in Haemodialysis Patients: A Randomized Controlled Trial
Tunneled dialysis catheters (TDCs) remain a frequent form of vascular access for patients undergoing long-term haemodialysis (HD).
- Conditions
- Hemodialysis, Thrombolytic Therapy, Dialysis Access Dysfunction, Randomised Controlled Trial
- Trial name
- SHUT (NCT06802679)
- Testing
- Urokinase
- Where
- Singapore
- Volunteers
- 44 people
- Sponsor
- National Healthcare Group, Singapore
Thrombolytic Therapy, Acute Stroke
Improving In-hospital Stroke Service Utilisation in China
A cluster randomised controlled trial will be conducted, using hospital as randomisation unit. Hospitals in Zhejiang Province, China, will be randomised into two arms (1:1): an intervention arm and a control arm.
- Conditions
- Thrombolytic Therapy, Acute Stroke, Door to Treatment Time, Quality Improvement
- Trial name
- NCT03317639
- Testing
- Behaviour Change Wheel model guided intervention
- Where
- China
- Volunteers
- 1,634 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebrovascular Stroke, Thrombolytic Therapy
Thromboelastometry and Ischemic Stroke (ThromboPredict)
In ischemic stroke, the recanalization rate after intravenous thrombolysis has been estimated to be less than 50% in patients with proximal intracranial artery occlusion; this rate is greater than 80% after endovascular…
- Conditions
- Cerebrovascular Stroke, Thrombolytic Therapy, Mechanical Thrombectomy
- Trial name
- NCT04870684
- Testing
- thromboelastometry test
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
The Aim the Study is to Collect and Analyze Data on Patients With Acute Ischemic Stroke During Intravenous Thrombolytic Therapy With Alteplase
Russian Prospective Multicenter Registry Study of Intravenous Thrombolytic Therapy for Acute Ischemic Stroke
Russian prospective multicenter registry study of intravenous thrombolytic therapy for acute ischemic stroke.
- Trial name
- IVT-AIS-R (NCT04674293)
- Testing
- Revelisa
- Where
- Russia
- Volunteers
- 500 people
- Sponsor
- Federal Center of Cerebrovascular Pathology and Stroke, Russian Federation Ministry of Health
Stroke, Acute, Thrombolytic Therapy
Thrombolysis Outcome in Ischemic Stroke
Consecutive patients with diagnosis of acute ischemic stroke and candidate of thrombolytic therapy during Jan 2017-Mar 2019 in BuAli Sina Hospital ,Sari, Iran, enrolled to this cohort study.
- Conditions
- Stroke, Acute, Thrombolytic Therapy, Alteplase, Mortality
- Trial name
- TOSSI (NCT04309357)
- Testing
- Alteplase
- Where
- Iran
- Volunteers
- 214 people
- Sponsor
- Mazandaran University of Medical Sciences
Acute Stroke, Thrombolytic Therapy
Evaluation of the Effectiveness of Thrombolytic Therapy in Acute Ischemic Stroke Patients Using NIRS
Investigators aim to study effectiveness of systemic thrombolytic therapy on acute ischemic stroke patients with near infrared spectroscopy.
- Conditions
- Acute Stroke, Thrombolytic Therapy, Stroke, Ischemic
- Trial name
- E-NESE (NCT03621917)
- Testing
- Near-infrared spectroscopy reading
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Dokuz Eylul University
Myocardial Infarction, Percutaneous Coronary Intervention
Effects of Intracoronary Prourokinase on the Coronary Flow During Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction
The purpose of this study is to determine whether intracoronary selective thrombolysis are more effective than tirofiban on the coronary flow during primary percutaneous coronary intervention for the acute myocardial infarction.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Thrombolytic Therapy
- Trial name
- ERUPTION (NCT02131220)
- Testing
- Prourokinase, Tirofiban, normal saline
- Where
- China
- Volunteers
- 362 people
- Sponsor
- Fudan University
Angiographically Confirmed Acute Massive Pulmonary Embolism Treated With Endovascular Mechanical Fragmentation and Thrombolytic Therapy
Pradaxa or Warfarin for Prevention of Recurrent VTE in Patients With Angiographically Confirmed Acute Massive Pulmonary Embolism undergoIng Endovascular Mechanical Fragmentation and Thrombolytic Therapy
A prospective randomised controlled study to evaluate outcomes of the treatment with pradaxa or warfarin for prevention of recurrent DVT in patients with angiographically confirmed acute massive pulmonary embolism undergoIng…
- Trial name
- Re-Spire (NCT02979561)
- Testing
- Dabigatran Etexilate, Warfarin
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Ischemic Stroke, Thrombolytic Therapy
Mild Hypothermia After Endovascular Treatment in Acute Ischemic Stroke
To study safety and feasibility of mild therapeutic hypothermia after successful recanalization by mechanical endovascular treatment in patients with acute ischemic stroke and proximal arterial occlusion.
- Trial name
- HELMET (NCT02985060)
- Testing
- Arctic Sun, Standard treatment, Saline
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Thrombolytic Therapy, Thrombolysis
Submassive Pulmonary Embolism Experience With EKOS
This single site study evaluates the efficacy of ultrasound accelerated thrombolysis using EKOS Endovascular Device with a standard infusion of thrombolytics for treatment of PE
- Conditions
- Thrombolytic Therapy, Thrombolysis, Mechanical Thrombolysis, Pulmonary Embolism
- Trial name
- SPEEK (NCT02926742)
- Testing
- EkoSonic Endovascular System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Krishna Mannava, MD, FACS, RPVI