Clinical trials: Telomere Shortening, active
Aging, Obesity
Obesity and Aging: Impacts of Nutritional Counseling and Physical Exercise on Telomeres and Senescence Parameters
The study will involve 80 elderly women, 40 eutrophic and 40 obese, divided into four groups, each with n=20. 1) Eutrophic Group (EG) undergoing only nutritional counseling (NC), 2) Eutrophic Group with NC and combined training…
- Conditions
- Aging, Obesity, Nutrition, Exercise
- Trial name
- NCT07479940
- Testing
- Combined Training, Nutritional Counseling
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Telomere Shortening, Aging
TA-65 and Aging Associated Microvascular Dysfunction
The goal of this clinical trial is to test whether activation of telomerase with a dietary supplement (TA-65) improves microvascular function.
- Conditions
- Telomere Shortening, Aging, Vascular Diseases
- Trial name
- NCT05598359
- Testing
- TA-65
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Telomere Length in Healthy Controls
Telomeres and T-cell Receptor Excision Circles (TRECs) From Peripheral Blood in Normal Subjects Over Time
The Investigators have established a cohort of patients with recent-onset inflammatory arthritis called Early Undifferentiated PolyArthritis (EUPA). This cohort was established to define novel biomarkers of poor outcomes.
- Trial name
- NCT01982890
- Testing
- Control
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Telomere Shortening, Bone Marrow Failure
Study to Evaluate of EXG34217 in Patients With Telomere Biology Disorders With Bone Marrow Failure
This is a Phase I/II, open label, single center study to assess the safety and tolerability of EXG34217 in bone marrow failure patients with telomere biology disorders.
- Trial name
- NCT04211714
- Testing
- EXG34217
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Elixirgen Therapeutics, Inc.