Clinical trials: TACS
Alzheimer Disease
tACS for Amyloid-β Reduction in Alzheimer's Disease
Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration.
- Trial name
- NCT03290326
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Chronic Stroke, Rehabilitation
Effect of tACS on the Recovery of Motor Control of the Upper Limb and Cerebral Connectivity in Chronic Stroke Patients
This project seeks to evaluate the effect of transcranial alternating current stimulation (tACS) on the recovery of motor control of the upper limb and associated neuronal synchrony during a 14-sessions (5-week) rehabilitation…
- Trial name
- tACS (NCT05947318)
- Testing
- transcranial alternating current stimulation 70 Hz, Training, transcranial alternating current stimulation 7 Hz
- Where
- Chile
- Volunteers
- 59 people
- Sponsor
- Universidad Metropolitana de Ciencias de la Educacion
Primary Hypertension
High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS) for Hypertension: A Randomized Controlled Trial
This study focuses on individuals with primary hypertension, with the main objective of investigating the effectiveness and safety of high-intensity transcranial alternating current stimulation (Hi-tACS) as a non-invasive…
- Trial name
- NCT07566650
- Testing
- Active High-Intensity Transcranial Alternating Current Stimulation (Hi-tACS)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuanwu Hospital, Beijing
Transcranial Alternating Current Stimulation, Depressive Disorder
Intervention Effect of High Definition Transcranial Alternating Current Stimulation (HD-tACS) on Depressive Disorder
To investigate the intervention effect of high definition transcranial alternating current stimulation (HD-tACS) on suicidal ideation in patients with depressive disorder and its underlying neural mechanism by magnetic resonance…
- Trial name
- NCT05932706
- Testing
- High definition transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Transcranial Alternating Current Stimulation, Frontotemporal Dementia (FTD)
Transcranial Alternating Current Stimulation in Frontotemporal Dementia
The aim of the study is to evaluate the safety, feasibility, clinical and biological efficacy, and predictors of efficacy of an intervention consisting of transcranial alternating current stimulation (tACS) in patients with…
- Trial name
- BetaTACSFTD (NCT07505784)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Aphasia
The Effect of Dual-target tACS Combined With Speech Training on Repetition Disorder After Stroke
This clinical trial aims to study whether dual-target transcranial alternating current stimulation (tACS) applied to the auditory and motor brain region can improve repetition disorder in people with stroke, and to evaluate the…
- Trial name
- NCT07347327
- Testing
- speech training, real tACS
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Ke Dong, MD
Healthy
Effect of Transcranial Alternative Current Stimulation at Alpha Frequency (α-tACS) on Stressed Healthy Subjects
stress. Notably, several studies reported that stress could alter impulsivity, source monitoring, and time perception. Several mechanisms are involved in the response to a stress factor, among them the…
- Trial name
- CAF-TAS (NCT06229002)
- Testing
- Transcranial alternative current stimulation (tACS) at alpha frequency
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Schizophrenia; Negative Type, Transcranial Alternating Current Stimulation
Efficacy of Hi-tACS for Schizophrenia Negative Symptoms
The goal of this clinical trial is to investigate whether Hi-tACS is effective and safe in treating negative symptoms of schizophrenia. Schizophrenic patients will receive treatment (Hi-tACS or shame stimulation) for 2 weeks.
- Trial name
- NCT06888726
- Testing
- High-intensity transcranial alternating current stimulation (Hi-tACS)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Mental Health Center
Transcranial Alternating Current Stimulation
Atlas of Intracranial Recordings on Cortical Responses After Functional tACS
By analyzing the SEEG recordings, we explore the range of cortical functional responses to strings of 77.5Hz stimulations delivered by tACS,
- Trial name
- AIRCRAFT (NCT04560959)
- Testing
- tACS
- Volunteers
- 30 people
- Sponsor
- Xuanwu Hospital, Beijing
Premenstrual Dysphoric Disorder
Targeting Inter-Hemispheric Alpha Coherence With tACS To Treat PMDD
Purpose: Using transcranial alternating current stimulation (tACS), we will study whether tACS induces changes in prefrontal alpha oscillatory frequencies in women with premenstrual dysphoric disorder (PMDD) and whether tACS…
- Trial name
- NCT02362191
- Testing
- Alternating Current Stimulator
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Visual Impairment, Stroke
Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery
This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients…
- Conditions
- Visual Impairment, Stroke, Parkinson Disease
- Trial name
- R4V (NCT05220449)
- Testing
- Cross-frequency dual-site tACS
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Attention Deficit Disorder With Hyperactivity (ADHD)
Gamma tACS in Attention-Deficit/Hyperactivity Disorder
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by symptoms of inattention, impulsivity, and hyperactivity.
- Trial name
- NCT07145593
- Testing
- Application tACS- 80 Hz, Application tACS -40 Hz, Application TACS - (6-80 Hz)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Depression Disorders, Non-suicidal Self-injury
The Impact of Beta-band Transcranial Alternating Current Stimulation (tACS) on Impulse Inhibition in Adolescents With Non-suicidal Self-injury
This clinical trial aims to determine whether beta-band transcranial alternating current stimulation (tACS) can improve impulse inhibition in adolescents with non-suicidal self-injury (NSSI) and to evaluate its safety.
- Trial name
- NCT07152925
- Testing
- Beta-frequency transcranial alternating current stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Schizophrenia / Schizoaffective Disorder
tACS for Self-Other Boundary in Schizophrenia
This clinical trial investigates whether a non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve the ability to distinguish between "self" and "others" in patients with…
- Trial name
- NCT07818668
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chunyan Zhu
Transcranial Alternating Current Stimulation
Effects of Gamma-tACS on EEG Periodic Activity
In this study on healthy subjects, the effect of transcranial alternating current stimulation (tACS) will be investigated. In particular, the distinction between periodic and aperiodic electroencephalogram (EEG) activity will be…
- Trial name
- GAMMAtACS (NCT05809076)
- Testing
- real tACS
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Schizophrenia
Efficacy and Safety of tACS vs tDCS in Schizophrenia
This clinical trial aims to compare the efficacy and safety of transcranial Alternating current stimulation (tACS) vs. transcranial Direct current stimulation (tDCS) vs. sham stimulation in chronic schizophrenia.
- Trial name
- NCT06494124
- Testing
- transcranial Alternating current stimulation (tACS), transcranial Direct current stimulation (tDCS)
- Where
- India
- Volunteers
- 90 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Healthy
Modulating Speech Perception With Current Stimulation
This study aims to further develop tACS as a tool to improve speech perception, by manipulation of brain-speech synchronisation ("entrainment"), thereby transforming a promising approach into a technique that can benefit to…
- Trial name
- SPEECHSTIM (NCT05446350)
- Testing
- transcranial alternating current stimulation (tACS), electroencephalography (EEG), brain imaging (fMRI)
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Negative Symptoms in Schizophrenia, Cognition Function
tACS to Improve Negative Symptoms & Cognition in Long-term Hospitalized Schizophrenia Patients.
This study aims to evaluate the efficacy of transcranial alternating current stimulation (tACS) on negative symptoms and cognitive function in long-term hospitalized patients with schizophrenia.
- Trial name
- NCT07074704
- Testing
- Hi-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji University
Motor Recovery
tACS for Sensory Motor Recovery After Stroke
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for motor recovery in stroke survivors.
- Trial name
- NCT06029062
- Testing
- tACS 10Hz, tACS 20Hz
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- The University of Texas Health Science Center, Houston
Depression, Major Depressive Disorder
Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Depression
The purpose of this research study is to study closed-loop transcranial alternating current stimulation (tACS) to determine its effects on symptoms of depression in people with major depressive disorder.
- Conditions
- Depression, Major Depressive Disorder, tACS
- Trial name
- CLACS (NCT05772702)
- Testing
- Closed-loop tACS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Electromedical Products International, Inc.