Clinical trials: Surgery, active
Surgery
Premedication Gastric Ultrasound
The primary objective of this study is to assess gastric volume in fasted children using ultrasound before and after drinking premedication.
- Trial name
- NCT04130022
- Testing
- Point-of-Care Ultrasound
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kevin Spellman
Colorectal Cancer, Surgery
Impact of a Multidisciplinary Approach in the Perioperative Geriatrics Unit on Functional Status of Patients Aged 70 and Over Operated on for Colorectal Cancer
Health establishments encourage the development of specific care pathways for the elderly by supporting Geriatric Peri-Operative Units (GPOU).
- Trial name
- DIGER (NCT05993923)
- Testing
- GPOU
- Where
- 4 sites in France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Surgery-Complications, Disability Physical
The STRIVE Before Surgery Trial
The STRIVE Before Surgery Trial evaluates patient-reported disability at 90 days after surgery following participating in a home-based multimodal prehabilitation program supported through an online platform.
- Trial name
- STRIVE (NCT06511258)
- Testing
- Prehabilitation
- Where
- Canada
- Volunteers
- 902 people
- Sponsor
- Ottawa Hospital Research Institute
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Right Ventricular Function, Prone Position
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right ventricular failure (RVF) is a common complication to cardiac surgery, which is associated to mortality, kidney failure, stroke, prolonged mechanical ventilation and ICU stay.
- Conditions
- Right Ventricular Function, Prone Position, Atelectasis, Atelectases, Postoperative Pulmonary
- Trial name
- BAROLO (NCT07632027)
- Testing
- Prone position
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Sahlgrenska University Hospital
Preoperative Anxiety, Orthopedic Surgery
Preoperative Anxiety and One-year Patient-reported Outcomes in Orthopedic Surgery Patients Receiving Enhanced Recovery After Surgery or Conventional Care
This study investigates whether an Enhanced Recovery After Surgery (ERAS) program can help orthopedic surgery patients feel less anxious before their operation and recover better one year after surgery, compared to conventional…
- Conditions
- Preoperative Anxiety, Orthopedic Surgery, Patient Reported Outcome (PRO)
- Trial name
- ERAS-APO (NCT07706244)
- Testing
- Enhanced Recovery After Surgery (ERAS) pathway, Conventional care group
- Where
- Taiwan
- Volunteers
- 220 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Gynecologic Surgery, General Anesthesia
Long-term Follow-up of Bio-signals and Quality of Recovery Following Implementation of ERAS Based on the Mobile Application
The goal of this clinical trial is to evaluate the effect of an Enhanced Recovery After Surgery (ERAS) protocol in patients undergoing gynecologic laparoscopic or robotic surgery under general anesthesia.
- Trial name
- NCT07868952
- Testing
- Enhanced Recovery After Surgery, Usual Care
- Where
- South Korea
- Volunteers
- 350 people
- Sponsor
- Wonju Severance Christian Hospital
Internal Jugular Vein Anatomy, Common Carotid Artery Anatomy
Ultrasound Mapping of the Anatomical Relationship Between the Right Internal Jugular Vein and Carotid Artery
This prospective observational study will describe the anatomical relationship between two major blood vessels on the right side of the neck: the internal jugular vein and the common carotid artery.
- Conditions
- Internal Jugular Vein Anatomy, Common Carotid Artery Anatomy, Cardiac Surgery
- Trial name
- IJVCCA (NCT07893080)
- Testing
- Standardized Ultrasound Imaging and Computer-Assisted Angular Mapping
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara City Hospital Bilkent
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Cardiac Surgery With Cardiopulmonary Bypass, Postoperative Delirium
Mechanisms and Intervention Strategies of Perioperative Glycemic Variability on Postoperative Delirium
Delirium is a sudden change in attention, thinking, and awareness that can occur after heart surgery. It may slow recovery and is associated with longer hospital stays and poorer health outcomes.
- Trial name
- NCT07893353
- Testing
- Intranasal insulin-20U, Intranasal insulin-40U, Intranasal Saline
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Fujian Medical University Union Hospital
Thoracic Surgery, Video-assisted
Sensory Anesthesia Achieved Through Different Paravertebral Block Approaches for Post-Op Pain Management After VATS Lung Resection
Video-assisted thoracoscopic lung resection (VATS) is a minimally invasive surgical approach frequently used in the treatment of lung cancers.
- Conditions
- Thoracic Surgery, Video-assisted, Paravertebral Block
- Trial name
- NCT07063602
- Testing
- Evaluation of the hypoesthesia of the thorax
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Thoracic Surgery
Thoracic Surgery by SHURUI Single-Port Surgical Robot
The introduction of single-port surgical robot has been a transformative breakthrough in the medical field, representing a significant advancement in minimally invasive procedures.
- Trial name
- NCT07255703
- Testing
- Device: Endoscopic Surgical System, SR-ENS-600
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Emergency Abdominal Surgery, Opioid Sparing Anaesthesia
Effect of Opioid-sparing Anesthesia on Quality of Recovery After Emergency Laparotomy
Opioids are widely used during anesthesia for pain control, but they cause many side effects-such as nausea, constipation, respiratory depression, dependence, and delayed recovery.
- Trial name
- NCT07262242
- Testing
- Lidocaine (drug), Fentanyl (IV)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Penis/Surgery, Penis/Injuries
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
The goal of this randomized interventional clinical trial is to learn if placement of a thin layer of fatty tissue (fat graft) beneath a split-thickness skin graft on the surface of the penis improved outcomes of surgery in men…
- Conditions
- Penis/Surgery, Penis/Injuries, Penile Skin, Adult-Acquired Buried Penis
- Trial name
- NCT07316491
- Testing
- Autologous fat grafting, Genitourinary Reconstruction with Split-Thickness Skin Grafting
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Prostate Cancer Surgery, Prostate Cancer Metastatic Disease
Safety and Efficacy of OTL78
This is a trial to assess the accuracy of an imaging agent, PSMA targeted fluorescent dye OTL78 (zopocianine), in combination with Near InfraRed (NIR) fluorescent imaging, to improve the detection of malignant (growing in an…
- Trial name
- NCT07725523
- Testing
- 0.06 mg/kg ZOPOCIANINE given 1-7 days prior to surgery
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Clinton Bahler
Spinal Surgery for Lumbar Spinal Stenosis (LSS)
Activity Post Spinal Surgery Engagement Trial
Back pain can be disabling, limiting the ability to walk and to engage in physical activity. For patients with degenerative lumbar spinal stenosis, decompressive surgery often provides substantial pain relief and improved…
- Trial name
- ASSET (NCT07825480)
- Testing
- Wrist based activity tracker wear, Basic Study Activities, Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Brigham and Women's Hospital
Heart Valve Surgery, Acute Kidney Injury
Effects of Remote Ischemic Preconditioning at Different Time Phases in Patients Undergoing Heart Valve Surgery
Patients undergoing heart valve surgery require cardiopulmonary bypass, a procedure that can lead to a temporary reduction in blood flow to major organs and subsequent ischemia-reperfusion injury, thereby triggering postoperative…
- Trial name
- NCT07888634
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Fujian Medical University Union Hospital
Thoracotomy, Toracosurgery
Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric…
- Conditions
- Thoracotomy, Toracosurgery, Thoracic Anesthesia, Older Adults (65 Years and Older)
- Trial name
- NCT07889336
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Liposuction, Body Contouring Surgery
A Prospective Randomized Study to Evaluate the Benefits of Harmonic Vibration Liposuction
The purpose of this study is to compare two devices, PAL device manufactured by Microaire Surgical Instruments, LLC and the Harmonic Vibrator liposuction device to see if there is a difference in the outcome of the procedure with…
- Trial name
- HarmonicLipo (NCT07889427)
- Testing
- Harmonic Vibration
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Lipocosm, LLC