ThoracotomyNCT07889336
Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Lung Resection
An observational study of Thoracotomy and Toracosurgery, run by Ankara Ataturk Sanatorium Training and Research Hospital at 1 site in Turkey (Türkiye).
Trial summary
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric patients-serve as risk factors for the development of nutritional deficiencies. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Thoracotomy, Toracosurgery, Thoracic Anesthesia
- How many people
- 69 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 30 Nov 2026to 30 Dec 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Patients undergoing elective thoracic surgery; patients scheduled for lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients classified as ASA 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.
Inclusion criteria: Patients undergoing elective thoracic surgery; patients scheduled for lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients classified as ASA 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.
- Exclusion criteria: Patients classified as ASA IV or higher; patients scheduled for emergency surgery; patients under 65 years of age; patients with a history of prior thoracic surgery; patients in GOLD group 3 or 4; patients with systemic inflammatory disease; patients with preoperative chronic pain who regularly use anti-inflammatory or analgesic medication; patients with a history of pulmonary embolism (PE).
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Ankara Ataturk Sanatoryum Research and Training Hospital
Ankara, keçiören, 06290
abdullah TAŞDİZEN, MD, +90 507 053 48 49, abtasdizen@gmail.com
About this study
Official title: The Relationship Between Preoperative Nutritional Status and Postoperative Outcomes in Geriatric Patients Undergoing Pulmonary Resection Via Thoracotomy: A Prospective Observational Study
Malnutrition is a common comorbidity in patients undergoing thoracic surgery. Furthermore, chronic diseases, polypharmacy, low nutrient intake, reduced appetite, and psychological factors-all frequently observed in geriatric patients-serve as risk factors for the development of nutritional deficiencies. Consequently, it is crucial to address the issue of malnutrition in geriatric patients-who often present with these risk factors-and to ensure that a nutritional status assessment is performed prior to thoracic surgery. While numerous screening tools are currently available to assess nutritional status in the elderly, there is no established "gold standard." Although it has been suggested that these nutritional screening tools can serve as prognostic indicators for geriatric surgical patients, the relationship between these tools and postoperative outcomes-such as pain, complications, and length of hospital stay-has not yet been fully evaluated in geriatric patients undergoing lung resection. This study aims to determine the relationship between preoperative nutritional status and postoperative outcomes in patients undergoing lung resection-an area lacking sufficient literature-and to investigate whether preoperative nutritional support can reduce postoperative complications in this patient population.Patients will undergo preoperative assessment, and data regarding those meeting inclusion criteria will be recorded. This includes routine blood tests, age, height, body weight, BMI, gender, diagnoses, ASA and ARISCAT scores, the surgery performed, durations of surgery/anesthesia/one-lung ventilation, intraoperative fluids and IV agents administered, fluid balance, any complications arising during the procedure or postoperative follow-up (up to discharge), Visual Analog Scale (VAS) scores at postoperative hours 1, 2, 4, 8, 16, and 24, Charlson Comorbidity Index, Clinical Frailty Scale (CFS), and nutritional status (GNRI, NRS-2002, PNI, MNA-SF).
- Inclusion criteria: Patients undergoing elective thoracic surgery; patients undergoing lung resection via thoracotomy; patients who have provided informed consent; patients over 65 years of age; patients assessed as ASA class 1, 2, or 3; patients with a body mass index (BMI) between 18 and 35.
- Exclusion criteria: Patients with ASA class IV or higher; patients scheduled for emergency surgery; patients under 65 years of age; patients with a history of prior thoracic surgery; patients in GOLD groups 3 or 4; patients with systemic inflammatory disease; patients with preoperative chronic pain who regularly use anti-inflammatories/analgesics; patients with a history of pulmonary thromboembolism (PTE).
- Conditions
- Thoracotomy, Toracosurgery, Thoracic Anesthesia, Older Adults (65 Years and Older), Lung Resection Surgery
- Keywords
- thoracotomy, older adults(65 years and older), lung resection surgery, lung lobectomy, pneumonectomy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Patients over the age of 65 who underwent lung resection via thoracotomy. | Patients over the age of 65 who underwent lung resection via thoracotomy. |
What is being measured
The primary outcome is the main question the study is designed to answer.
the correlation between preoperative nutritional status and postoperative results in geriatric patients undergoing lung resection by thoracotomy.
The primary outcome variable of the study is the evaluation of the correlation between preoperative nutritional status and postoperative outcomes in geriatric patients undergoing lung resection by thoracotomy.Patients will be evaluated preoperatively and patients who meet the inclusion criteria will have routine blood tests, age, height, body weight, BMI, gender, diagnoses, ASA and ARISCAT scores, surgery performed, duration of surgery/anesthesia/single lung ventilation, fluid and iv agents administered intraoperatively, fluid balance, advanced complications, if any, during the procedure or during postoperative follow-up until discharge, postoperative 1., 2., 4., 8., 16. and 24. visual Analog Scale(VAS), Charlson Comorbidity Index, Clinical Frailty Scale(CFS), nutritional status of GNRI, NRS-2002, PNI, MNA-SF and forms will be recorded by filling out
Measured: after surgery up to 30 days
Secondary outcomes (1)
comparison of the indicated nutritional risk screening tools in terms of the predictability of postoperative outcomes in geriatric patients who will undergo lung resection with thoracatomy.
The nutritional screening tools such as nutritional status of GNRI, NRS-2002, PNI, MNA-SF will be compared to determine which one is better at predicting postoperative outcomes.
Measured: after surgery up to 30 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Oct 2026
- Study start30 Nov 2026 (estimated)
- Primary completion30 Oct 2027 (estimated)
- Study completion30 Dec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for ThoracotomyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 69 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Abdullah TAŞDİZEN, Ankara Ataturk Sanatorium Training and Research Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07889336
- Sponsor's protocol ID
- abd01
- Status last verified
- Oct 2026
- First submitted
- 16 Oct 2026
- Last updated
- 22 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Gunaydin B, Kurtipek O. Elektif Non-Kardiyak Cerrahi Gecirecek Eriskinlerin Pre-Operatif Degerlendirme Kilavuzu: Avrupa Anesteziyoloji Dernegi'nden Guncellenmis Onerilerin Ozeti: Pre-Operative Evaluation of Adults Undergoing Elective Noncardiac Surgery: Summary of the Updated Guideline From the European Society of Anaesthesiology. Turk J Anaesthesiol Reanim. 2019 Jun;47(3):244-272. doi: 10.5152/TJAR.2019.150419. Epub 2018 Jun 1. No abstract available. Turkish.
PubMed 31183475Buja A, De Luca G, Dal Moro S, Mammana M, Zanovello A, Miola S, Boemo DG, Storti I, Bovo P, Zorzetto F, Schiavon M, Rea F. Cost-consequence analysis of the enhanced recovery after surgery protocol in major lung resection with minimally invasive technique (VATS). Front Surg. 2024 Oct 30;11:1471070. doi: 10.3389/fsurg.2024.1471070. eCollection 2024.
PubMed 39539512Le Pimpec Barthes F, Mordant P, Pricopi C, Foucault C, Dujon A, Riquet M. [The place of surgery in metastatic non-small cell lung cancer]. Rev Mal Respir. 2012 Mar;29(3):376-83. doi: 10.1016/j.rmr.2011.07.010. Epub 2012 Feb 22. French.
PubMed 22440301Gao S, Liao X, He Y, Tan Z, Jiang L, Yang J. The effectiveness of multimodal prehabilitation on functional capacity and clinical outcomes in patients undergoing elective laparoscopic colorectal cancer surgery: a systematic review of meta-analysis of randomized controlled trials. J Cancer Surviv. 2026 Mar 24. doi: 10.1007/s11764-026-01978-7. Online ahead of print.
PubMed 41872610Hunter JM. Postoperative pulmonary complications and reversal agents. Br J Anaesth. 2018 Mar;120(3):604. doi: 10.1016/j.bja.2017.12.024. Epub 2018 Jan 17. No abstract available.
PubMed 29452820