Clinical trials: Thoracotomy
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo
Chest Tube Removal
Clinical Trial Evaluating the Optimal Technique for Chest Tube Removal
There are two commonly used methods to remove chest tubes following thoracotomy. One is to remove the chest tube at maximum inspiration, (patient is asked to take a deep breath in and hold it), and the other is to pull the chest…
- Trial name
- NCT00873587
- Testing
- Chest tube pull on inspiration, Expiration
- Where
- United States
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pneumothorax, Pleural Effusion
Drainage Amount for Removal of Thoracostomy Tube
The purpose of this study is to determine whether chest tubes can be safely removed without considering how much fluid is draining through the tube.
- Trial name
- DARTT (NCT00575198)
- Testing
- No drainage threshold, Drainage <2 mL/kg
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- University of California, Davis
Lung Disease, Pulmonary Lobectomy
PleuraSeal Post Market Study (Europe)
To further characterize the PleuraSeal Sealant System as compared to standard of care (sutures and staples only) in subjects undergoing an elective pulmonary lobectomy and segmentectomy via open thoractomy.
- Trial name
- NCT00704171
- Testing
- Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System
- Where
- 9 sites in United States, Austria and 4 more
- Volunteers
- 121 people
- Sponsor
- Integra LifeSciences Corporation
Minimal Invasive Cardiac Surgery, Limited Right Anterior Thoracotomy for Mitral Valve Replacement
Efficacy of Limited Right Anterior Thoracotomy Versus Median Sternotomy for Mitral Valve Replacement
this study compare between two diffrent methods for approach mitral valve in mitral valve replacement throgh opening of the middle of the sternum by saw or through opening between 4th and 5th rib on the right side of the chest…
- Trial name
- NCT06869980
- Testing
- mitral valve replacement through limited right anterior thoractomy, mitral valve replacement through median sterntomy
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Zagazig University
Lung Cancer, Lobectomy
Medicoeconomic Evaluation of Two Surgical Techniques for Lobectomy in the Lung Cancer
This is a national study that involves the participation of 600 lung cancer patients indicated that treatment is ablation of the pulmonary lobe. This technique is called lobectomy.
- Trial name
- LungSco01 (NCT02502318)
- Testing
- Video-thoracoscopy, thoracotomy
- Where
- 10 sites in France
- Volunteers
- 261 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Lung Diseases, Lung Cancers
Optimizing Post-Thoracotomy Pain Management: Comparing Erector Spinae vs. Paravertebral Block in Thoracotomy Patients
This prospective, observational study included ASA class II-III patients aged 18-70 years who underwent elective unilateral lobectomy via a thoracotomy.
- Trial name
- NCT06964698
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Non Small Cell Lung Cancer
Multicentric Analysis of Predictors of N1 Upstaging After Resection of cStage-I NSCLC
Five papers showed a lower N1 nodal upstaging with video-assisted thoracic surgery (VATS) compared to open surgery in patients with cStage-I NSCLC .
- Trial name
- NUTS (NCT02730897)
- Testing
- Central/Peripheral
- Volunteers
- 956 people
- Sponsor
- University Hospital, Gasthuisberg
Esketamine, Pain
Esketamine and Butorphanol for Post-Lobectomy Pain
Post-thoracotomy pain syndrome (PTPS) affects respiratory function, hindering sputum clearance and ventilation, and represents a significant complication of thoracic surgery.
- Conditions
- Esketamine, Pain, Post-thoracotomy Pain Syndrome, Thoracic Diseases
- Trial name
- NCT06398834
- Testing
- Esketamine, Butorphanol
- Where
- China
- Volunteers
- 223 people
- Sponsor
- Second People's Hospital of Hefei City
Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery
Our Aim is to identify patient risk factors and clinical practices associated with healthcare-acquired infections (HAIs) after cardiac surgery.
- Conditions
- Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Sepsis, Pneumonia
- Trial name
- HAI (NCT02068716)
- Where
- United States
- Volunteers
- 911,754 people
- Sponsor
- Dr. Donald Likosky
Chronic Post-thoracotomy Pain, Neuropathic Pain
SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery
This study aims to evaluate the efficacy of ultrasound-guided Serratus Posterior Superior (SPS) block compared to surgeon-administered intercostal blockade in preventing chronic pain at 3, 6, and 12 months following…
- Conditions
- Chronic Post-thoracotomy Pain, Neuropathic Pain, Postoperative Pain, Acute
- Trial name
- NCT07436806
- Testing
- SPS block, Surgical Intercostal Blockade.
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Medipol University
Cancer of the Lung, Lung Cancer
Circulating Tumor DNA in Patients at High Risk for Lung Cancer
Patients who are about to undergo a diagnostic or therapeutic bronchoscopy or thoracic surgery without a distant history of cancer will have their blood drawn for measurement of circulating tumor DNA (ctDNA) to validate the…
- Conditions
- Cancer of the Lung, Lung Cancer, Lung Neoplasms, Adenocarcinoma of the Lung
- Trial name
- NCT02715102
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Pathway Genomics
Lung Transplantation
Chronic Pain After Lung Transplantation, an Incidence Study
This is an investigation on the frequency of chronic pain amongst recipients after lung transplantation. Factors relating to the development of chronic pain are investigated.
- Trial name
- NCT00745654
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pain, Postoperative
Chronic Pain Following Thoracic Surgery
Pain that persists after the healing of a surgical wound has previously been described as an important, but often unrecognized clinical problem.
- Trial name
- PTPS-18 (NCT01144845)
- Testing
- Thoracic surgery
- Where
- Denmark
- Volunteers
- 702 people
- Sponsor
- University of Aarhus
Multiple Pulmonary Nodules
Fast Track Rehabilitation Following Video-assisted Lung Segmentectomy
Aim of this prospective randomized study is to assess the safety and efficacy of video-assisted lung segmentectomy (Group B) comparing with mini muscle-sparing thoracotomy (group A) during diagnostic process for pulmonary nodules.
- Trial name
- NCT01397045
- Testing
- VATS, Mini thoracotomy
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- Theagenio Cancer Hospital
Post-thoracotomy Pain Syndrome
IMPACT OF OPERATIVE POSITIONING ON THE DEVELOPMENT OF SHOULDER PAIN AFTER PULMONARY LOBECTOMY BY VATS
The investigators want to be able to show a 66% decrease in the incidence of shoulder pain in the "support" group compared to the "suspension" group.
- Trial name
- POVA (NCT04415242)
- Testing
- positioning
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Gastric Neoplasm
Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
To compare left thoraco-abdominal approach with abdominal and transhiatal approach to cardia or subcardia cancer
- Trial name
- NCT00149266
- Testing
- Surgery: abdominal and transhiatal approach, Surgery: left thoraco-abdominal approach
- Where
- Japan
- Volunteers
- 167 people
- Sponsor
- Japan Clinical Oncology Group
Siewert Type II Adenocarcinoma of Esophagogastric Junction
Right Versus Left Thoracic Surgical Approaches for Siewert II Gastroesophageal Junction Adenocarcinoma
To explore the 5-year overall survival (OS) of right versus left thoracic surgical approaches for patients with locally advanced Siewert II gastroesophageal junction adenocarcinoma treated by neoadjuvant chemotherapy
- Trial name
- NCT06644352
- Testing
- different thoracic surgical approaches
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences