Clinical trials: Suicide Prevention, active
Suicide, Attempted, Suicide Ideation
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
This multisite randomized controlled trial will compare two brief interventions for youth and young adults ages 12-24 following an acute care visit for suicide risk: the Stanley-Brown Safety Planning Intervention with follow-up…
- Conditions
- Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
- Trial name
- Project HOPE (NCT06151158)
- Testing
- Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
- Where
- 6 sites in United States
- Volunteers
- 484 people
- Sponsor
- Johns Hopkins University
Suicide Prevention, Social Media Users
Exploring The Effect of TikTok Trigger Warnings in a Clinical Sample of Youth at Risk of Suicide
Rates of suicide among Canadian youth have risen steadily over the past two decades, alongside rapid growth in social media use-especially TikTok.
- Trial name
- NCT07913854
- Testing
- Trigger Warning
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Suicide, Secure Firearm Storage
Reducing Firearm Suicide Among Veterans: Evaluating the Effectiveness of Peer-Delivered Lethal Means Counseling
Suicide prevention is a top priority for the Department of Veterans Affairs (VA), with a major emphasis on developing innovative and effective ways to prevent firearm suicide.
- Trial name
- NCT07033884
- Testing
- Peer Engagement and Exploration of Responsibility and Safety, Active Control
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicidal Behavior
Intravenous Ketamine for Acute Suicidal Crisis and Psychiatric Hospital Length of Stay
This randomized, double-blind, active placebo-controlled superiority trial will evaluate whether intravenous esketamine reduces time to psychiatric hospital discharge in adults hospitalized because of acute suicide risk.
- Trial name
- NCT07888933
- Testing
- Esketamine, Midazolam (Intravenous)
- Where
- Brazil
- Volunteers
- 106 people
- Sponsor
- University of Sao Paulo
Depressive Disorder, Major Depressive Disorder, Suicidal Ideation
Evaluation of a Multi-Layered Digital Phenotyping, Digital Safety Plan, and Pharmacogenomic Intervention for Suicide Prevention in Adults With Depression
The goal of this clinical trial is to learn if a multi-layered digital and pharmacogenomic intervention works to prevent suicide re-attempts in adults with depression.
- Conditions
- Depressive Disorder, Major Depressive Disorder, Suicidal Ideation, Suicide, Attempted, Suicide Prevention
- Trial name
- SMARTomicS (NCT07885722)
- Testing
- Digital Monitoring (Active/Passive EMA), Ecological Momentary Intervention (EMI) via Digital Safety Plan, Pharmacogenetic-Guided Care and Therapeutic Drug Monitoring
- Where
- Spain
- Volunteers
- 525 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Suicide
THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers
Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year.
- Trial name
- THRIVE (NCT07784634)
- Testing
- Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- University of Alabama at Birmingham
HIV - Human Immunodeficiency Virus, Suicide Prevention
IDEAS for Hope to Reduce Suicide Risk and Improve HIV Care Engagement in Tanzania
In this project, the investigators will conduct a clinical trial to test the effectiveness and implementation of IDEAS for Hope, a 3-session telehealth counseling intervention delivered by nurses, to reduce suicidality and…
- Trial name
- NCT07459218
- Testing
- IDEAS for Hope, Safety Planning Intervention
- Where
- Tanzania
- Volunteers
- 600 people
- Sponsor
- Duke University
Suicide
Rapid Personalization of Safety Plans for Psychiatrically Hospitalized Veterans at High-Risk for Suicide
Veterans psychiatrically hospitalized face significantly elevated suicide risk, particularly in the three months post-discharge.
- Trial name
- NCT07507786
- Testing
- Personalized Safety Plans, Safety Plans as Usual + Calls
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicide Prevention, Suicide
NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics
This study will adapt and evaluate an evidence-based suicide risk screening and follow-up program in two school-based health centers in West Virginia.
- Trial name
- NCT06808503
- Testing
- NIMH Clinical Pathway
- Where
- 3 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Suicide, Suicide Prevention
Peer Delivered Youth Suicide Prevention in Nepal
South Asia has the highest suicide rate in the world with important risk profile differences from high-income settings. Investigators will conduct formative research to co-design a package of brief interventions and…
- Trial name
- NCT07680179
- Testing
- Enhanced Usual Care (EUC), Youth-focused, Peer-delivered, Family-engaged Suicide Prevention Package (YPF-SuPP)
- Where
- Nepal
- Volunteers
- 160 people
- Sponsor
- Yale University
Risk Reduction Behavior, Suicide Prevention
SAFEGUARD Level Up Study
This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program.
- Conditions
- Risk Reduction Behavior, Suicide Prevention, Risky Behavior, Mental Health
- Trial name
- NCT07286955
- Testing
- Level Up
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Suicide Prevention
Caring Contacts Via Text Message for Suicidal Adolescents After Emergency Department Discharge
The goal of this pilot clinical trial is to learn if Caring Contacts (brief, hopeful, supportive text messages) can be delivered to adolescents with suicidal thoughts or behaviors after discharge from the emergency department…
- Trial name
- NCT07043764
- Testing
- Caring Contacts Text Messages
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Suicide Prevention, User Experience
Evaluation of the Quality of Chat Conversations With the Suicide Helpline Zelfmoordlijn 1813
Suicide remains a serious public health issue in Flanders. Every day, nearly three people die by suicide, and many more attempt it or struggle with suicidal thoughts.
- Conditions
- Suicide Prevention, User Experience, Suicide, Suicidal Ideation
- Trial name
- CHATQ-1813 (NCT07176156)
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 373 people
- Sponsor
- University Ghent
Suicide Prevention, Ketamine
Esketamine Versus Crisis Response Planning Versus Enhanced Treatment as Usual for Suicide Prevention: A Pragmatic Randomized Trial in a Brazilian Municipality (SAVE)
The SAVE study will test whether a single esketamine infusion or a single Crisis Response Planning session, each added to enhanced treatment as usual, reduces future suicide-related events compared with enhanced treatment as…
- Conditions
- Suicide Prevention, Ketamine, Crisis Response Plan
- Trial name
- SAVE (NCT07120477)
- Testing
- Intravenous Esketamine, Crisis Response Planning (CRP), Enhanced Treatment as Usual (eTAU)
- Where
- Brazil
- Volunteers
- 478 people
- Sponsor
- University of Sao Paulo
Mental Disease
Mental Health Reinforcement in Wayapi and Teko Communities in French Guiana : Evaluation of the Impact of a Mediation Based Activity in Municipalities of Camopi and Trois Saut in French Guiana
In French Guiana, Indigenous people experience high levels of psychological distress and higher rates of suicidal behavior than the rest of the population.
- Trial name
- MCS Impact (NCT07808801)
- Where
- French Guiana
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Suicide Prevention
Suicide Prevention After Community Care Discharge
The study is of high importance to Veterans' health because it will study a suicide prevention intervention in a Veteran population that is at high risk of suicide but has not been a specific focus of the Veteran Affairs' (VA's)…
- Trial name
- NCT06596044
- Testing
- VA BIC, Standard Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Suicide, Suicide Prevention
Caring Connections Youth Suicide Detection and Intervention Study
The goal of this pilot randomized control trial (RCT) is to test the feasibility of Caring Connections, a Culturally Adapted Linking Individuals Needing Care (CA-LINC) suicide prevention care coordination intervention for…
- Conditions
- Suicide, Suicide Prevention, Suicide Ideation, Suicide Attempt
- Trial name
- CA-LINC (NCT06353711)
- Testing
- Caring Connections, Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Suicide Prevention, Suicide Safety Planning
Suicide Safety Planning
The goal of this clinical trial is to learn the best way to provide suicide prevention care to adults receiving outpatient mental health care.
- Conditions
- Suicide Prevention, Suicide Safety Planning, Suicidal Ideation, Suicide Attempt
- Trial name
- STAY (NCT07783490)
- Testing
- Local Care Continuity, Centralized Care Navigation
- Where
- United States
- Volunteers
- 176,000 people
- Sponsor
- Kaiser Permanente