Risk Reduction BehaviorNCT07286955
SAFEGUARD Level Up Study
A study testing Level Up in people with Risk Reduction Behavior and Suicide Prevention, run by Uniformed Services University of the Health Sciences at 1 site in United States.
Trial summary
This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal-related behaviors (SRBs) and other harmful behaviors, improve mental health, enhance job… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Risk Reduction Behavior, Suicide Prevention, Risky Behavior
- What is being tested?
- Level Up
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5,000 participants
- Where
- 1 siteUnited States
- Study dates
- 10 Dec 2025to Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Active duty Soldiers Active duty Soldiers who are currently stationed at Fort Hood, Texas and are members of a participating platoon.
Who cannot join
- Soldiers who are not present at the time of recruitment
- Soldiers who are under the age of 18 years old
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
3ABCT, 1st Cavalry Division
Fort Hood, Texas, 76544
3ABCT Operations Officer, 410-491-8560, dalton.r.coe.mil@army.mil
About this study
This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal-related behaviors (SRBs) and other harmful behaviors, improve mental health, enhance job performance, and reduce early military separation. The Level Up program components will be made available to participants through an online platform or mobile app that can be downloaded onto their personal mobile devices. These training materials will help Soldiers learn and practice skills. The Level Up program will also involve personalized messages from a Level Up trainer and virtual booster sessions. Active duty Soldiers who are currently stationed at Fort Hood, Texas and are members of a participating platoon will be randomized to receive either Level Up or Training as Usual (TAU). Participants will complete baseline and follow up surveys 1, 3, and 6 months post-baseline.
Read the detailed description
The first four years of service is widely known to be an especially high-risk period for suicide-related behaviors (SRBs) among Soldiers. In addition, most suicides occur among younger Soldiers aged 17-24 years-old (40%) and 25-29 years-old (26%) compared to older Soldiers (30-34 years-old= 18%, 35+ years-old = 16%). Situational stressors are prevalent among Soldiers who die by suicide, particularly in the areas of relationship problems (42%), workplace issues (29%), and financial issues (10%). These findings align with growing literature attesting to the direct relationship between such situational stressors and later SRBs in the military This time is also marked by high rates of other harmful behaviors and of early separation from the Army. The Army invests billions of dollars in recruiting and training, yet many new Soldiers leave the service early or experience serious events like suicidal behaviors. Exposure to situational stressors involving such areas of life as romantic relationships and finances increases risk for suicide and other harmful behaviors. Implementing universal training programs to prevent these types of negative outcomes before they arise have enormous potential to bolster the mental toughness of new Soldiers during this difficult transition. The proposed project aims to prevent suicide-related behaviors (SRBs) and other behaviors qualifying for a Serious Incident Report (SIR) through an innovative, universal life skills program delivered to Soldiers at Fort Hood. The proposed project will test the effectiveness of a recently developed, evidence-based training program designed to build life skills and coping strategies that can protect against suicide, other harmful behaviors, poor work performance, and premature separation. A majority of Soldiers in a typical operational unit are of enlisted rank and 30 years of age or younger, which as discussed earlier is the demographic of highest risk for suicide. Therefore, the purpose of this study will remain focused on evaluating the effectiveness of Level Up for reducing SRBs among early career Soldiers.
This project will evaluate the effectiveness of Level Up, a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal thoughts and behaviors, improve mental health, enhance job performance, and reduce early military separation. Previous studies show that building skills like stress management, problem-solving, and healthy communication can protect against SRBs and related problem behaviors. However, many of these programs failed to show long-term impact, partly due to limited engagement. Level Up is designed to overcome these limitations by combining interactive learning, mobile technology, personalized coaching, and on-demand virtual booster sessions. This hybrid format is intended to help Soldiers refresh their skills and engage with content at their preferred pace and rhythm. The Level Up program components include: 1) four weekly 2-hour live group sessions, 2) a mobile app/online platform/workbook with brief, interactive self-guided exercises in core skill areas (e.g., managing stress, tactical thinking, healthy relationships), 3) personalized coaching via messages from trained staff during the first month of app use, and 4) virtual booster sessions over one year, focused on practical domains like finances, leadership, promotion tips, and personal relationships. Soldiers will be randomized to receive either Level Up or TAU.
The Level Up program content draws from evidence-based psychological methods such as Cognitive Behavioral Therapy, Acceptance and Commitment Therapy, and motivational coaching adapted to fit military culture and tailored to be relevant, accessible, and engaging for Soldiers. By equipping them with essential life skills and support, the program aims to reduce SRBs and other behaviors qualifying for SIRs, develop psychosocial skills, and increase career success and satisfaction.
If effective, Level Up could be implemented Army-wide as a universal prevention program to improve mental health, readiness, and retention. There are minimal risks as the interventions are educational, although some participants may experience brief emotional discomfort during skill practice or reflection. All participants can opt out at any time, and all are provided with resources and additional support as needed. This study could have a transformative impact on military suicide prevention efforts, especially during early service when Soldiers are most vulnerable. By evaluating this scalable program in a large, real-world setting, the research will provide clear evidence about its benefits for reducing suicide and improving readiness. Results will also support development of predictive tools to identify which Soldiers may benefit most from added support. Findings will be shared across the Department of War to inform policy, training, and future resilience-building programs-ultimately improving the health, performance, and quality of life of Soldiers across the Force.
- Conditions
- Risk Reduction Behavior, Suicide Prevention, Risky Behavior, Mental Health, Resilience, Performance at Work
- Being tested
- Level Up
- Keywords
- Military Health, Suicide Prevention, Harmful Behaviors, Life Skills Training, First Duty Location, Active-duty Military, Risk Reduction, Prevention, Level Up
- Medical subject headings
- Risk Reduction Behavior, Suicide Prevention, Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Level UpBehavioural
The Level Up program components include:
- Four weekly 2-hour live group sessions
- A mobile app/online platform/workbook with brief, interactive self-guided exercises in core skill areas (e.g., managing stress, tactical thinking, healthy relationships)
- Personalized coaching via messages from trained Level Up staff during the first month of app use
- Virtual booster sessions over one year, focused on practical domains like finances, leadership, promotion tips, and personal relationships
| Study group | Role | What they receive |
|---|---|---|
| Level Up Program | Experimental | The Level Up program is a hybrid intervention combining interactive learning, mobile/online technology, personalized coaching, and on-demand virtual booster sessions. The evidence-based training program was designed to build life skills and coping strategies that can protect against suicide, other harmful behaviors, poor work performance, and premature separation during a Soldier's first duty assignment. Receives: Behavioral: Level Up |
| Training As Usual (TAU) | No intervention | TAU will serve as the study control condition. TAU will consist of other mandatory training activities determined by their unit. TAU activities include access to a variety of standard Army training resources at Fort Hood that support the mental health and well-being of Soldiers and lower risk of harmful behaviors. |
What is being measured
The primary outcome is the main question the study is designed to answer.
The occurrence of any harmful behavior
The occurrence of any harmful behavior, either self-reported in follow up surveys or administratively reported
Measured: Within the 12 months after intervention randomization
The occurrence of any suicide-related behavior
The occurrence of any suicide-related behavior, either self-reported in follow up surveys or administratively reported
Measured: Within the 12 months after intervention randomization
Secondary outcomes (33)
The occurrence of any premature separations from service
Measured: Within the 12 months after intervention randomization
Poor performance as indicated either by written reprimands, designations in the NCOER, a corrective action plan, remedial training, flagging actions, demotion, Article 15, or barred reenlistment
Measured: Within the 12 months after intervention randomization
Personal deployment readiness
Walter Reed Army Institute of Research Land Combat Survey; Scale ranges from 4-20; Higher scores indicate higher perceived readiness
Measured: Within the 6 months after intervention randomization
Emotionality
Emotion Reactivity Scale (ERS) ; Scale ranges from0-4; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Job satisfaction
3-item Job Satisfaction Scale; Scale ranges from 3-15; Higher scores indicate higher perceived job satisfaction
Measured: Within the 6 months after intervention randomization
Depression symptom severity
Patient Health Questionnaire-2 (PHQ-2); Scale ranges from 0-8; Higher scores indicate more severe symptoms
Measured: Within the 6 months after intervention randomization
Anxiety symptom severity
Generalized Anxiety Disorder-2 (GAD-2); Scale ranges from 0-8; Higher scores indicate more severe symptoms
Measured: Within the 6 months after intervention randomization
Incidence of traumatic brain injuries
Number of traumatic brain injuries; based on the Army STARRS Surveys; No scale range; number indicates greater number of traumatic brain injuries
Measured: Within the 6 months after intervention randomization
Lifetime history of various mental/emotional health problems
Family History Screen (FHS); Scale ranges from 0-1; 0=No; 1=Yes
Measured: Within the 6 months after intervention randomization
Chronic stress severity
Personal Life Stress Scale (PLS); Scale ranges from 0-50; Higher scores indicate greater chronic stress severity
Measured: Within the 6 months after intervention randomization
Mental toughness
Sports Mental Toughness Questionnaire (SMTQ); Scale ranges from 5-25; Higher scores indicate higher confidence \& constancy
Measured: Within the 6 months after intervention randomization
History of suicidal ideation, plan, & attempt
Columbia-Suicide Severity Rating Scale (C-SSRS) Full scale Baseline/Screening; Scale ranges from 0-1 0=No; 1=Yes
Measured: Within the 6 months after intervention randomization
Positive social networks
Supportive \& Negative Social Interaction Scale (SIS); Scale ranges from 0-8; Higher scores indicate more positive/negative social support
Measured: Within the 6 months after intervention randomization
Negative social networks
Supportive \& Negative Social Interaction Scale (SIS); Scale ranges from 0-8; Higher scores indicate more positive/negative social support
Measured: Within the 6 months after intervention randomization
Mattering/belonging
General Mattering Scale; Scale ranges from 0-20; Higher scores indicate higher perceived mattering to others
Measured: Within the 6 months after intervention randomization
Loneliness
3-Item Loneliness Screener; Scale ranges from 0-16; Higher scores indicate more frequency-severity of loneliness
Measured: Within the 6 months after intervention randomization
Adverse childhood events & trauma
Childhood Trauma Questionnaire - Short Form (CTQ-SF) ; Scale ranges from 0-44; Higher scores indicate more childhood maltreatment
Measured: Within the 6 months after intervention randomization
Conscientiousness
Big Five Inventory (BFI)16 \& Personality Inventory for DSM-5 Brief Form (PID-5-BF); Scale ranges from 0-8; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Mastery
Pearlin \& Schooler's Psychological Coping Resources Measure; Scale ranges from 0-8; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Openness
120-item International Personality Item Pool (IPIP); Scale ranges from 0-4; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Problem-solving ability
Social Problem Solving Inventory-Revised (SPSI-R); Scale ranges from 0-8; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Psychological well-being
Flourishing Scale; Scale ranges from 0-12; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Resilience
Army STARRS Resilience Scale; Scale ranges from 0-16; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Self-esteem
Rosenberg Self-Esteem Scale; Scale ranges from 0-8; Higher scores indicate lower of each adaptive trait
Measured: Within the 6 months after intervention randomization
Anxious, Cyclothymic, Depressive, & Hyperthymic temperament
Revised NEO Personality Inventory (NEO-PI-R) \& the Temperament Evaluation of Memphis, Pisa, Paris \& San Diego-autoquestionnaire version (TEMPS-A); Scale ranges from 0-8 for each temperament; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Borderline personality
McLean Screening Instrument for Borderline Personality Disorder; Scale ranges from 0-16; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Anger-hostility
Big Five Inventory (BFI)16 \& Personality Inventory for DSM-5 Brief Form (PID-5-BF); Scale ranges from 0-8; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Impulsivity/negative urgency
Impulsive Behavior Scale - Short Form (SUPPS-P); Scale ranges from 0-8; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Introversion
Eysenck Personality Questionnaire - Brief Version (EPQ-BV)28 \& Revised NEO Personality Inventory (NEO-PI-R); Scale ranges from 0-8; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Fearlessness about death
Acquired Capability for Suicide Scale; Scale ranges from 0-4; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Self-conscious
Widiger Five-Factor Rating Form - Revised31 \& NEO Five-Factor Inventory (NEO-FFI); Scale ranges from 0-8; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Vulnerability
NEO Five-Factor Inventory (NEO-FFI); Scale ranges from 0-4; Higher scores indicate higher of each maladaptive trait
Measured: Within the 6 months after intervention randomization
Frequency of risky behaviors
Unit Risk Inventory (URI); Scale ranges from 0-1; 0=Never; 1=At least less than once a month
Measured: Within the 6 months after intervention randomization
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Dec 2025
- Study start10 Dec 2025
- Primary completionDec 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Risk Reduction BehaviorStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 5,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Uniformed Services University of the Health Sciences
- Sponsor type
- US federal agency
- Collaborators
- Defense Health Agency, Harvard University, Henry M. Jackson Foundation for the Advancement of Military Medicine, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Walter Reed Army Institute of Research (WRAIR), University of Michigan
- Responsible party
- Sponsor
- Investigators
- Thomas H Nassif, PhD, Principal investigator, Uniformed Services University of the Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07286955
- Sponsor's protocol ID
- USUHS.2025-162
- Other IDs
- Federal Award # HU00012520025
- Status last verified
- Sep 2026
- First submitted
- 3 Dec 2025
- Last updated
- 25 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- SAFEGUARD Level Up Study
- ClinicalTrials.gov ID
- NCT07286955
- Acronym / sponsor ID
- USUHS.2025-162
- Conditions
- Risk Reduction Behavior, Suicide Prevention, Risky Behavior, Mental Health, Resilience, Performance at Work
- Keywords
- Military Health, Suicide Prevention, Harmful Behaviors, Life Skills Training, First Duty Location, Active-duty Military, Risk Reduction, Prevention
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 5,000 participants (estimated)
- Lead sponsor
- Uniformed Services University of the Health SciencesUS federal agency
- Collaborators
- Defense Health Agency, Harvard University, Henry M. Jackson Foundation for the Advancement of Military Medicine, Beth Israel Deaconess Medical Center, Massachusetts General Hospital, Walter Reed Army Institute of Research (WRAIR), University of Michigan
- Study start
- 10 Dec 2025 (actual)
- Primary completion
- Dec 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 16 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project will evaluate the effectiveness of Level Up: Boost Your Life Skills ("Level Up"), a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal-related behaviors (SRBs) and other harmful behaviors, improve mental health, enhance job performance, and reduce early military separation. The Level Up program components will be made available to participants through an online platform or mobile app that can be downloaded onto their personal mobile devices. These training materials will help Soldiers learn and practice skills. The Level Up program will also involve personalized messages from a Level Up trainer and virtual booster sessions. Active duty Soldiers who are currently stationed at Fort Hood, Texas and are members of a participating platoon will be randomized to receive either Level Up or Training as Usual (TAU). Participants will complete baseline and follow up surveys 1, 3, and 6 months post-baseline.
Detailed description
The first four years of service is widely known to be an especially high-risk period for suicide-related behaviors (SRBs) among Soldiers. In addition, most suicides occur among younger Soldiers aged 17-24 years-old (40%) and 25-29 years-old (26%) compared to older Soldiers (30-34 years-old= 18%, 35+ years-old = 16%). Situational stressors are prevalent among Soldiers who die by suicide, particularly in the areas of relationship problems (42%), workplace issues (29%), and financial issues (10%). These findings align with growing literature attesting to the direct relationship between such situational stressors and later SRBs in the military This time is also marked by high rates of other harmful behaviors and of early separation from the Army. The Army invests billions of dollars in recruiting and training, yet many new Soldiers leave the service early or experience serious events like suicidal behaviors. Exposure to situational stressors involving such areas of life as romantic relationships and finances increases risk for suicide and other harmful behaviors. Implementing universal training programs to prevent these types of negative outcomes before they arise have enormous potential to bolster the mental toughness of new Soldiers during this difficult transition. The proposed project aims to prevent suicide-related behaviors (SRBs) and other behaviors qualifying for a Serious Incident Report (SIR) through an innovative, universal life skills program delivered to Soldiers at Fort Hood. The proposed project will test the effectiveness of a recently developed, evidence-based training program designed to build life skills and coping strategies that can protect against suicide, other harmful behaviors, poor work performance, and premature separation. A majority of Soldiers in a typical operational unit are of enlisted rank and 30 years of age or younger, which as discussed earlier is the demographic of highest risk for suicide. Therefore, the purpose of this study will remain focused on evaluating the effectiveness of Level Up for reducing SRBs among early career Soldiers.
This project will evaluate the effectiveness of Level Up, a strengths based, military-specific life skills training program. The goal is to determine whether Level Up can decrease suicidal thoughts and behaviors, improve mental health, enhance job performance, and reduce early military separation. Previous studies show that building skills like stress management, problem-solving, and healthy communication can protect against SRBs and related problem behaviors. However, many of these programs failed to show long-term impact, partly due to limited engagement. Level Up is designed to overcome these limitations by combining interactive learning, mobile technology, personalized coaching, and on-demand virtual booster sessions. This hybrid format is intended to help Soldiers refresh their skills and engage with content at their preferred pace and rhythm. The Level Up program components include: 1) four weekly 2-hour live group sessions, 2) a mobile app/online platform/workbook with brief, interactive self-guided exercises in core skill areas (e.g., managing stress, tactical thinking, healthy relationships), 3) personalized coaching via messages from trained staff during the first month of app use, and 4) virtual booster sessions over one year, focused on practical domains like finances, leadership, promotion tips, and personal relationships. Soldiers will be randomized to receive either Level Up or TAU.
The Level Up program content draws from evidence-based psychological methods such as Cognitive Behavioral Therapy, Acceptance and Commitment Therapy, and motivational coaching adapted to fit military culture and tailored to be relevant, accessible, and engaging for Soldiers. By equipping them with essential life skills and support, the program aims to reduce SRBs and other behaviors qualifying for SIRs, develop psychosocial skills, and increase career success and satisfaction.
If effective, Level Up could be implemented Army-wide as a universal prevention program to improve mental health, readiness, and retention. There are minimal risks as the interventions are educational, although some participants may experience brief emotional discomfort during skill practice or reflection. All participants can opt out at any time, and all are provided with resources and additional support as needed. This study could have a transformative impact on military suicide prevention efforts, especially during early service when Soldiers are most vulnerable. By evaluating this scalable program in a large, real-world setting, the research will provide clear evidence about its benefits for reducing suicide and improving readiness. Results will also support development of predictive tools to identify which Soldiers may benefit most from added support. Findings will be shared across the Department of War to inform policy, training, and future resilience-building programs-ultimately improving the health, performance, and quality of life of Soldiers across the Force.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Level Up Program | Experimental | Behavioral: Level UpThe Level Up program is a hybrid intervention combining interactive learning, mobile/online technology, personalized coaching, and on-demand virtual booster sessions. The evidence-based training program was designed to build life skills and coping strategies that can protect against suicide, other harmful behaviors, poor work performance, and premature separation during a Soldier's first duty assignment. |
| Training As Usual (TAU) | No intervention | –TAU will serve as the study control condition. TAU will consist of other mandatory training activities determined by their unit. TAU activities include access to a variety of standard Army training resources at Fort Hood that support the mental health and well-being of Soldiers and lower risk of harmful behaviors. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Active duty Soldiers Active duty Soldiers who are currently stationed at Fort Hood, Texas and are members of a participating platoon.
Key exclusion criteria (2 listed)
- Soldiers who are not present at the time of recruitment
- Soldiers who are under the age of 18 years old
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Level UpThe Level Up program components include: * Four weekly 2-hour live group sessions * A mobile app/online platform/workbook with brief, interactive self-guided exercises in core skill areas (e.g., managing stress, tactical thinking, healthy relationships) * Personalized coaching via messages from trained Level Up staff during the first month of app use * Virtual booster sessions over one year, focused on practical domains like finances, leadership, promotion tips, and personal relationships | Behavioural | Level Up Program |
Primary outcome
The occurrence of any harmful behavior
Time frame: Within the 12 months after intervention randomization
The occurrence of any harmful behavior, either self-reported in follow up surveys or administratively reported
The occurrence of any suicide-related behavior
Time frame: Within the 12 months after intervention randomization
The occurrence of any suicide-related behavior, either self-reported in follow up surveys or administratively reported
33 secondary outcomes
The occurrence of any premature separations from service
Time frame: Within the 12 months after intervention randomization
Poor performance as indicated either by written reprimands, designations in the NCOER, a corrective action plan, remedial training, flagging actions, demotion, Article 15, or barred reenlistment
Time frame: Within the 12 months after intervention randomization
Personal deployment readiness
Time frame: Within the 6 months after intervention randomization
Emotionality
Time frame: Within the 6 months after intervention randomization
Job satisfaction
Time frame: Within the 6 months after intervention randomization
Depression symptom severity
Time frame: Within the 6 months after intervention randomization
Anxiety symptom severity
Time frame: Within the 6 months after intervention randomization
Incidence of traumatic brain injuries
Time frame: Within the 6 months after intervention randomization
Lifetime history of various mental/emotional health problems
Time frame: Within the 6 months after intervention randomization
Chronic stress severity
Time frame: Within the 6 months after intervention randomization
Mental toughness
Time frame: Within the 6 months after intervention randomization
History of suicidal ideation, plan, & attempt
Time frame: Within the 6 months after intervention randomization
Positive social networks
Time frame: Within the 6 months after intervention randomization
Negative social networks
Time frame: Within the 6 months after intervention randomization
Mattering/belonging
Time frame: Within the 6 months after intervention randomization
Loneliness
Time frame: Within the 6 months after intervention randomization
Adverse childhood events & trauma
Time frame: Within the 6 months after intervention randomization
Conscientiousness
Time frame: Within the 6 months after intervention randomization
Mastery
Time frame: Within the 6 months after intervention randomization
Openness
Time frame: Within the 6 months after intervention randomization
Problem-solving ability
Time frame: Within the 6 months after intervention randomization
Psychological well-being
Time frame: Within the 6 months after intervention randomization
Resilience
Time frame: Within the 6 months after intervention randomization
Self-esteem
Time frame: Within the 6 months after intervention randomization
Anxious, Cyclothymic, Depressive, & Hyperthymic temperament
Time frame: Within the 6 months after intervention randomization
Borderline personality
Time frame: Within the 6 months after intervention randomization
Anger-hostility
Time frame: Within the 6 months after intervention randomization
Impulsivity/negative urgency
Time frame: Within the 6 months after intervention randomization
Introversion
Time frame: Within the 6 months after intervention randomization
Fearlessness about death
Time frame: Within the 6 months after intervention randomization
Self-conscious
Time frame: Within the 6 months after intervention randomization
Vulnerability
Time frame: Within the 6 months after intervention randomization
Frequency of risky behaviors
Time frame: Within the 6 months after intervention randomization
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Thomas H Nassif, PhD principal investigator
Uniformed Services University of the Health Sciences
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Level Up in people with Risk Reduction Behavior and Suicide Prevention, run by Uniformed Services University of the Health Sciences at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 25 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Level Up Study Team (301-660-6297, level-up-study-ggg@usuhs.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The occurrence of any harmful behavior (time frame: Within the 12 months after intervention randomization). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Sep 2026.