Clinical trials: Stroke Hemorrhagic
Hemorrhagic Stroke, Augmented Renal Clearance
ARC in Hemorrhagic Stroke
To determine the incidence and predictors of augmented renal clearance (ARC) in patients with hemorrhagic stroke.
- Trial name
- NCT02386202
- Testing
- No intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke, Acute Stroke
Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)
The goal of this clinical trial is to evaluate whether a multicomponent nurse-led intervention (BEST CARE ICTUS_HC) can reduce stroke-related complications and improve recovery in adults (18 years and older) hospitalized with an…
- Conditions
- Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- BESTCAREICTUS (NCT07627399)
- Testing
- BEST CARE ICTUS_HC BUNDLE
- Where
- 4 sites in Spain
- Volunteers
- 700 people
- Sponsor
- University of Malaga
Stroke, Vascular Accident
PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE)
Stroke-associated pneumonia (SAP) is a grave complication of stroke and one of the most important predictors for patients' poor outcomes.
- Conditions
- Stroke, Vascular Accident, Intracranial Hemorrhages, Intracerebral Hemorrhage
- Trial name
- PRO-CHASE (NCT05419193)
- Testing
- Propranolol Hydrochloride, control group
- Where
- 12 sites in China
- Volunteers
- 168 people
- Sponsor
- Beijing Tiantan Hospital
Intracerebral Hemorrhage (ICH), Hemorrhagic Stroke, Intracerebral
Spleen Volume Change Predicts 45-Day Mortality in Neurocritical Care: A Prospective Cohort Study
This study investigates whether changes in spleen size over 72 hours can help predict the risk of death within 45 days in patients who were admitted to the emergency department with a type of bleeding in the brain called…
- Conditions
- Intracerebral Hemorrhage (ICH), Hemorrhagic Stroke, Intracerebral, Neurocritical Care, Acute Brain Injury
- Trial name
- SCOPE (NCT07132996)
- Testing
- POCUS-based Splenic Volume Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Hematoma Brain, Large Basal Ganglia Hemorrhage
A Multicenter, RAndomlzed, coNtrolled, umBrella Trial fOr Minimally Invasive Neurosurgery With Al-assisted Robotic guidanCe for Hemorrhagic Stroke: Large Basal Ganglia Hemorrhage
This substudy is a prospective, multicenter, parallel-controlled, randomized controlled trial designed to evaluate whether robot-assisted endoscopic evacuation of large basal ganglia hematomas can improve patient outcomes…
- Trial name
- RAINBOW-LBH (NCT06484374)
- Testing
- Robot-Assisted Endoscopic Minimally Invasive Surgery, Traditional Surgical Approaches
- Where
- China
- Volunteers
- 198 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Intracerebral Hemorrhage
Chinese Multicenter Cohort Study of Intracerebral Hemorrhage
Spontaneous intracerebral hemorrhage is a severe form of stroke associated with high mortality and long-term disability. The Chinese Multicenter Cohort Study of Intracerebral Hemorrhage (CASA) is a prospective observational…
- Trial name
- CMCS-ICH (NCT07833410)
- Where
- China
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Cerebrovascular Event, Stent Stenosis
Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation
APICES trial is an investigator-initiated, multicenter, multicenter, randomized, double-blind, placebo-controlled clinical trial that plans to enroll 396 patients with a 1-year follow-up, including a neurovascular imaging…
- Conditions
- Cerebrovascular Event, Stent Stenosis, Ischemic Stroke, Hemorrhagic Stroke
- Trial name
- NCT06308952
- Testing
- Atorvastatin 20mg
- Where
- China
- Volunteers
- 354 people
- Sponsor
- Duan Chuanzhi
Brain Stem Hemorrhage, Robotic Surgical Procedures
A Multicenter, RAndomIzed, coNtrolled, umBrella Trial fOr Minimally Invasive Neurosurgery With AI-assisted Robotic guidanCe for Hemorrhagic Stroke
The purpose of this clinical trial is to observe the improvements in clinical symptoms and imaging outcomes for brainstem hemorrhage using robot-assisted stereotactic puncture, evaluate the clinical efficacy and safety of this…
- Trial name
- RAINBOW-BSH (NCT06459427)
- Testing
- Robot-assisted minimally invasive puncture and aspiration surgery, Standard medical management
- Where
- 15 sites in China
- Volunteers
- 142 people
- Sponsor
- Yanbing Yu
Ischemic Stroke, Hemorrhagic Stroke
Using Machine Learning and Biomarkers for Early Detection of Delayed Cerebral Ischemia
The overall goal of this project is to determine if machine learning and analysis of neurospecific biomarkers can enable early detection of upcoming or ongoing cerebral ischaemia in patients suffering from subarachnoid…
- Trial name
- CIDAIBASSAH (NCT06069973)
- Testing
- No intervention, observational study
- Where
- Sweden
- Volunteers
- 1,500 people
- Sponsor
- Sahlgrenska University Hospital
Intracerebral Hemorrhage
ROSE-Longitudinal Assessment With Neuroimaging
The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of…
- Trial name
- ROSE-LAWN (NCT05089331)
- Where
- 7 sites in United States
- Volunteers
- 250 people
- Sponsor
- State University of New York at Buffalo
Acute Cerebrovascular Accident, Cerebral Edema
Study of Stroke Related Edema Treatments
Stroke remains the fourth leading cause of death in the United States (second worldwide) and a leading cause of long-term disability, resulting in total direct and indirect costs of approximately $73.7 billion annually.
- Trial name
- NCT01954290
- Testing
- Conivaptan, Hypertonic saline, Mannitol
- Sponsor
- University of Florida
Acute Stroke
Essential Acute Stroke Care in Low Resource Settings: a Pilot studY
An investigator-initiated, evaluator-blinded, prospective, multi centre, before-and-after, effectiveness-implementation hybrid design study to assess the feasibility of essential acute stroke care in a low resource setting
- Trial name
- EASY (NCT04157231)
- Testing
- Acute stroke care Intervention arm
- Where
- 4 sites in Nigeria, Peru
- Volunteers
- 300 people
- Sponsor
- The George Institute
Intracerebral Hemorrhage
Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial
The objective of the rFVIIa for Acute Hemorrhagic Stroke Administered at Earliest Time (FASTEST) Trial is to establish the first treatment for acute spontaneous intracerebral hemorrhage (ICH) within a time window and subgroup of…
- Trial name
- FASTEST (NCT03496883)
- Testing
- Recombinant Activated Factor VII (rFVIIa)
- Where
- 88 sites in United States, Canada and 4 more
- Volunteers
- 860 people
- Sponsor
- Joseph Broderick, MD
Acute Stroke
BraiN20® Medical Device in Suspected Acute Stroke Patients
Time is Brain company (http://www.tibtimeisbrain.com/about_us/) developed BraiN20®, a medical device to assess the presence and characteristics of the N20 signal of SEP.
- Trial name
- PROMISE-GLOB (NCT06421337)
- Testing
- BraiN20(R)
- Where
- 3 sites in Spain
- Volunteers
- 500 people
- Sponsor
- Alicia Martínez Piñeiro
Ischemic Stroke, Hemorrhagic Stroke
Aerobic Exercise and Cognitive Training in Patients With Stroke
The goal of this clinical trial is to test the effects of aerobic exercise and BDNF on patients with ischemic and hemorrhagic stroke during a computerized cognitive training. The main questions it aims to answer are: 1.
- Trial name
- NCT05735405
- Testing
- Neuropsychological evaluation, BDNF evaluation, Pedaling as a moderate intensity aerobic exercise
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Ischemic, Stroke Hemorrhagic
Study on the Performance of a Machine Learning Algorithm Recognizing and Triaging Large Vessel Occlusions Using Non-contrast CT Scans
The goal of this prospective observational study is to assess the effectiveness and performance of Methinks AI stroke imaging software platform in acute Code Stroke patients, and as a comparator to study sites utilizing existing…
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Stroke, Acute, Brain Ischemia
- Trial name
- SMART-LVO (NCT06216457)
- Testing
- AI software for Stroke
- Volunteers
- 5,000 people
- Sponsor
- Methinks Software SL
Cardiovascular Complications, Hemorrhagic Disorders
Comparison of Accidents and Their Circumstances With Oral Anticoagulants
Differences in efficacy and safety between new oral anticoagulants (NOAC) and vitamin K antagonist (VKA) in real practice remain uncertain.
- Conditions
- Cardiovascular Complications, Hemorrhagic Disorders, Embolism and Thrombosis
- Trial name
- CACAO (NCT02376777)
- Testing
- Follow up
- Where
- 33 sites in France
- Volunteers
- 4,162 people
- Sponsor
- CNGE IRMG Association
Cerebrovascular Stroke, Intracranial Hemorrhages
Predictive Value of Infarction Volume on Hemorrhagic Transformation in Ischemic Stroke/TIA With Non-valve Atrial Fibrillation(NVAF) Patients Using Rivaroxaban
This study was aimed at patients with newly diagnosed stroke / TIA associated with nonvalvular atrial fibrillation. We will observe the effect of early using rivaroxaban anticoagulation on hemorrhagic transformation, and explore…
- Conditions
- Cerebrovascular Stroke, Intracranial Hemorrhages, Anticoagulant, Matrix Metalloproteinases
- Trial name
- NCT03772457
- Testing
- Rivaroxaban
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, CVA (Cerebrovascular Accident)
MORbidity PRevalence Estimate In StrokE
Information regarding the likely progress of post-stroke symptoms is vitally important to stroke survivors to allow them to plan for the future and to adjust to life after stroke.
- Conditions
- Stroke, CVA (Cerebrovascular Accident), CVA; Sequelae, Stroke, Ischemic
- Trial name
- MORe PREcISE (NCT03605381)
- Where
- 3 sites in United Kingdom
- Volunteers
- 500 people
- Sponsor
- Aneurin Bevan University Health Board