Clinical trials: Sternotomy, open to volunteers
Complete Revascularization, Coronary Artery Bypass Grafting
Complete Revascularization Via Inferior Part-sternotomy
To verify the effectiveness and safety of minimally invasive coronary artery bypass grafting for complete revascularization of multivessel coronary artery disease via inferior part-sternotomy, We aim to randomize 260 patients…
- Conditions
- Complete Revascularization, Coronary Artery Bypass Grafting, Multivessel Coronary Artery Disease
- Trial name
- NCT05835167
- Testing
- Inferior part-sternotomy, Full median sternotomy
- Volunteers
- 260 people
- Sponsor
- China National Center for Cardiovascular Diseases
Prehabilitation, Cardiac Surgery
Feasibility of Physical Prehabilitation for High-Risk Patients Undergoing Cardiac Surgery Via Sternotomy
Rationale Cardiac surgery via median sternotomy carries an elevated risk of postoperative complications and delayed functional recovery.
- Conditions
- Prehabilitation, Cardiac Surgery, Risk Assesment, Aortic Valve
- Trial name
- PREPA-STER (NCT07893184)
- Testing
- Physical Prehabilitation Intervention
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Pain, Sternotomy
Comparison of the Efficacy of Combined Transversus Thoracic Plane Block and Serratus Anterior Plane Block Versus Erector Spinae Plane Block in the Management of Sternotomy Pain
Background and Purpose: Median sternotomy is the standard surgical approach for cardiac procedures, yet it is associated with significant postoperative pain.
- Conditions
- Postoperative Pain, Sternotomy, Nerve Block, Patient Outcome Assessment
- Trial name
- NCT07452627
- Testing
- TTP Block, ESP Block, SAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Cardiac Surgery Subjects
Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery
The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids. The objective of the study is to try to predict a patient's analgesic needs based on their objectively…
- Trial name
- NCT07513974
- Testing
- Measure of the minimal pain threshold with an algometer
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Septal Defect
Deep Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Patients Undergoing Primary Repair of Septal Defects Via Median Sternotomy
In this study we are aiming to compare the Erector Spinae Plane Block and the Deep Parasternal intercostal plane block as regard to their technique, application and outcome in order to describe the most suitable method for…
- Trial name
- NCT06873906
- Testing
- Deep Parasternal intercostal plane block, Erector Spinae Plane Block, conventional analgesic regimen
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Cardiac Surgery, Sternotomy
Affecting Factors for Chronic Pain After Sternotomy
Chronic pain is common complication of surgery procedures. Rates of mortalits is getting lower in cardiac surgery. This situation has brought us to focus morbidity and long term life quality.
- Conditions
- Cardiac Surgery, Sternotomy, Pain, Acute, Pain, Chronic
- Trial name
- NCT06534372
- Testing
- Open cardiac surgery with sternotomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara Etlik City Hospital
Postoperative Pain, Sternotomy
Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is associated with significant intraoperative and postoperative pain, often requiring substantial opioid administration.
- Conditions
- Postoperative Pain, Sternotomy, Opioid Consumption, Intraoperative Pain Control
- Trial name
- NCT07315308
- Testing
- Deep Parasternal Intercostal Plane Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Pain, Postoperative
Gabapentin to Reduce Opioid Use Postoperatively (GROUP) in Children
The primary objective of this study is to determine if the peri and post operative use of gabapentin in children reduces the need for narcotics after thoracic surgery.
- Trial name
- NCT04724252
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Davis
Sternotomy Closure,Open Heart Surgery
Botulinum Toxin Injection After Sternotomies to Improve Scar Aspect and Impact
Sternotomy scars, which are localized in a high-tension area are often dystrophic, hypertrophic or keloidal, and can be difficult to accept to patients who already endured a heavy intervention with high psychologic impact.
- Trial name
- BotuCiSter (NCT07013240)
- Testing
- Botulinum toxin injection
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Bordeaux
Ascending Aortic Aneurysm
Full Sternotomy vs Mini-sternotomy for Ascending Aortic Pathology
This study investigates outcomes after hemiarch repair in patients with chronic ascending aortic disease. The patients will be divided into two groups according to surgical approach: 100 patients will undergo hemiarch repair via…
- Trial name
- NCT07386028
- Testing
- Full sternotomy, J-shaped mini-sternotomy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Tomsk Cardiology Research Institute
Coronary Artery Bypass, Off-Pump, Minimally Invasive Cardiac Surgery
MInithoraCotomy vs Sternotomy for Multivessel Coronary Artery Bypass Grafting: A Partially Randomized Patient Preference Trial Assessing Quality of Life and Patency Outcomes
This trial will address essential questions of the efficacy and safety of MICS-CABG in addition to the quality of life and patency rate of the grafts.
- Trial name
- NCT04795193
- Testing
- Minimal invasive coronary surgery, Off-pump coronary artery bypass surgery
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Peking University Third Hospital
Retrospective Review, Cerclage
Enhanced Sternal Closure With Montage or Montage-CT to Evaluate Post-Operative Opioid Use Following Median Sternotomy
This is a retrospective study based on analysis real world data obtained from hospitals that have adopted use of Montage or Montage-CT for use following sternotomy.
- Conditions
- Retrospective Review, Cerclage, Pain Management
- Trial name
- NCT07215546
- Testing
- Montage or Montage CT
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Abyrx, Inc.
Bypass Surgery, Arrythmia
Parasternal Intercostal Plane Catheter for Pain Control After CABG Surgery
Coronary artery bypass graft (CABG) surgery performed via sternotomy (incision of the breastbone) can cause severe pain after surgery; this can slow recovery and increase the need for opioid pain relievers.
- Conditions
- Bypass Surgery, Arrythmia, Postoperative Pain
- Trial name
- PIP-PAIN (NCT07759570)
- Testing
- Parasternal blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Koc University Hospital
CABG, Physiological Parameter
The Effect of Virtual Reality and Eye Mask During Dressing After CABG Surgery
This study aims to evaluate the effects of virtual reality (VR) and eye mask (EM) applications on pain, anxiety, and physiological parameters during dressing after Coronary Artery Bypass Graft (CABG) surgery.
- Conditions
- CABG, Physiological Parameter, Postoperative Pain, Postoperative Anxiety
- Trial name
- CABG (NCT07039812)
- Testing
- Virtual Reality Headset, Eye Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Sternal Instability After Median Sternotomy
Comparison of Supra-abdominal ex Versus Infra-abdominal With Laser on Median Sternotomy
the aim of this study is to find out the differences between the effect of supra- abdomen exercises and the effect of infra-abdomen exercise combined with LASER And the effect of LOW LEVEL LASER only on sternal instability.
- Trial name
- LLL/CABG (NCT07381387)
- Testing
- supra abdomen resisted exercises combined with LLL + Traditional cardiac rehabilitation program of phase one, ): patients will infra abdomen resisted exercises combined with LLL +Traditional cardiac rehabilitation program of phase one., patients will receive Traditional cardiac rehabilitation program of phase one with LLL
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Atrial Fibrillation (AF), Cardiac Surgery
Isolation of Pulmonary Veins Using the Box Technique in Patients Undergoing Sternotomy
Atrial Fibrillation (AF) is the most common cardiac arrhythmia worldwide, affecting approximately 2.8% of the population, with prevalence increasing with age.
- Trial name
- BoxTer (NCT07312149)
- Testing
- Collection of study data from patient records
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Sternotomy, Cardiovascular Diseases
RCT on T-REX Twente Regimen Effects on Quality of Life and Mobilisation for Cardiac Surgery Patients After Sternotomy
The goal of this study is whether the T-REX Twente precautions have a positive impact on the quality of life (MAcNew QLMI), level of physical activity, and reduction of fear of movement in heart patients after a total median…
- Conditions
- Sternotomy, Cardiovascular Diseases, Physical Inactivity, Quality of Life
- Trial name
- T-REX Twente (NCT06115759)
- Testing
- T-REX Twente precautions, Usual (restrictive) sternal precautions
- Where
- Netherlands
- Volunteers
- 154 people
- Sponsor
- Medisch Spectrum Twente
Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD)
Effects of Myofascial Release on Cardiac Patients After Median Sternotomy
After deciding to join this study and signing the informed consent form, participants will undergo the following interventions: All participants will receive a preoperative assessment (Tp) before surgery.
- Conditions
- Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD), Valve Heart Disease
- Trial name
- NCT07649330
- Testing
- myofascial release+Routine Physical Therapy, Routine Physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Siou-Pin Huang
Sternotomy
SuperCable vs. Conventional Steel Wire for Closure After a Median Sternotomy
During certain heart surgeries, the sternum is opened and must then be closed securely. The study compares two closure methods - steel wires and SuperCable - in terms of stability, healing, and patient satisfaction.
- Trial name
- SURE (NCT07251881)
- Testing
- SuperCable®, Steel Wires
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Zurich