Clinical trials: Sternotomy
Congenital Heart Disease, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
Comparison of Erector Spinae Plane Block and Modified Pectoral Fascial Plane Block for Postoperative Analgesia in Pediatric Cardiac Surgery
Postoperative pain management is an essential component of perioperative care in pediatric congenital cardiac surgery. Regional anesthesia techniques, including the erector spinae plane block (ESPB) and modified pectoral fascial…
- Conditions
- Congenital Heart Disease, Postoperative Pain After Cardiac Surgery Via Median Sternotomy, Anesthesia
- Trial name
- NCT07740915
- Testing
- Ultrasound-Guided Erector Spinae Plane Block, Ultrasound-Guided Modified Pectoral Fascial Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Coronary Artery Bypass Graft (CABG), Postoperative Pain
Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery
Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications.
- Conditions
- Coronary Artery Bypass Graft (CABG), Postoperative Pain, Sternotomy
- Trial name
- BLOCKCABG (NCT07587320)
- Testing
- Multimodal Fascial Plane Block Package, Standard Postoperative Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Saglik Bilimleri Universitesi
Cardiac Surgery, Median Sternotomy
Early Rehabilitation in Patients Following Major Cardiac Surgery: Changes in Functional Capacity and Energy Efficiency in Walking and ADLs.
The main objective of this clinical trial is to evaluate exercise capacity before and after an inpatient or outpatient rehabilitation program in patients following major cardiac surgery.
- Trial name
- K5-POSTCCH (NCT07843316)
- Testing
- Use of COSMED K5, a portable metabolic system that allows real-time measurement of respiratory gas exchange, ventilation, and energy expenditure during physical activities.
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Chronic Postoperative Pain, Chronic Post-Sternotomy Pain
Parasternal Intercostal Nerve Block and Chronic Pain After Cardiac Surgery
Chronic post-sternotomy pain is a common but under-recognised complication of cardiac surgery, reported in roughly 11 to 56 percent of patients and capable of persisting for years after the operation.
- Conditions
- Chronic Postoperative Pain, Chronic Post-Sternotomy Pain, CABG, Sternotomy
- Trial name
- PINB-CPSP (NCT07818512)
- Testing
- Ultrasound-Guided Parasternal Intercostal Nerve Block, Bupivacaine 0.25%
- Volunteers
- 132 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Scheduled Cardiac Surgery, Sternotomy
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters
Postoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and…
- Conditions
- Scheduled Cardiac Surgery, Sternotomy, Elderly Patients, Obesity
- Trial name
- BLS-Sterno (NCT01828788)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Sternotomy
SuperCable vs. Conventional Steel Wire for Closure After a Median Sternotomy
During certain heart surgeries, the sternum is opened and must then be closed securely. The study compares two closure methods - steel wires and SuperCable - in terms of stability, healing, and patient satisfaction.
- Trial name
- SURE (NCT07251881)
- Testing
- SuperCable®, Steel Wires
- Where
- Switzerland
- Volunteers
- 86 people
- Sponsor
- University of Zurich
Postoperative Pain, Cardiac Surgery
ASPB-PIPB Combination in Cardiac Surgery
Cardiopulmonary bypass surgery is associated with significant postoperative pain, which may adversely affect respiratory function, delay mobilization, prolong hospital stay, and increase postoperative complications.
- Conditions
- Postoperative Pain, Cardiac Surgery, Cardiopulmonary Bypass, Median Sternotomy
- Trial name
- NCT07716943
- Testing
- Combined ASPB and PIPB, Anterior Serratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Cardiac Surgery, Sternotomy
ESP/PIF for Sternotomy
This is a randomized study. The purpose of this study is to evaluate the effect of post-surgical pain control of two types of peripheral nerve blocks, specifically erector spinal plane (ESP) block and pecto-intercostal fascial…
- Trial name
- NCT04985500
- Testing
- ESP block, PIF block, Ultrasound
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pulmonary Dysfunction, Median Sternotomy Recovery
FROST-STERN Trial: A Trial of Intraoperative Cryoablation for Post Operative Pain Management After Full Sternotomy
Background and Rationale: Open-heart surgery via a median sternotomy is associated with severe acute postoperative pain. This pain can impair a patient's ability to take deep breaths and cough effectively which increases the risk…
- Conditions
- Pulmonary Dysfunction, Median Sternotomy Recovery, Postoperative Pain
- Trial name
- FROST-STERN (NCT07637370)
- Testing
- Intercostal Nerve Cryoablation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Postoperative Pain, Cardiac Surgery
Parasternal Block Versus Wound Infiltration for Pain After Median Sternotomy:A Salivary Opiorphin-Based Study
This study evaluated the effects of parasternal block and wound site infiltration on postoperative pain in patients undergoing median sternotomy.
- Conditions
- Postoperative Pain, Cardiac Surgery, Median Sternotomy
- Trial name
- NCT07621744
- Testing
- Parasternal blocks, Wound Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ataturk University
Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy
Effect of Positioning and ACBT on Pulmonary Complications After Cardiac Surgery
The goal of this quasi-experimental clinical trial is to learn if position management combined with the Active Cycle of Breathing Techniques (ACBT) works to reduce postoperative pulmonary complications in adult patients…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Cardiac Surgery With Sternotomy, Atelectasis, Postoperative Pneumonia
- Trial name
- P-ACBT (NCT07612033)
- Testing
- Structured Position Management Protocol, Active Cycle of Breathing Techniques (ACBT)
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Assiut University
Chronic Pain, Postoperative, Sternotomy Pain
Early Screening of Chronic Post-sternotomy Pain Using the DN4-i Questionnaire
Chronic post-sternotomy pain (CPSP) is a common complication after cardiac surgery, with a reported prevalence between 30% and 50%.
- Trial name
- DEPDN4i (NCT07603271)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Institute Arnault Tzanck, France
Bariatric Surgery, Cardiac Surgery With Sternotomy
Suzetrigine-enhanced MultimOdal Opioid-sparing THerapy in Cardiac and Bariatric SURGery
This is prospective, randomized study. The purpose of this study is to evaluate whether the addition of Suzetrigine to well established multimodal pain regimen for participants undergoing bariatric patients undergoing weight-loss…
- Conditions
- Bariatric Surgery, Cardiac Surgery With Sternotomy, Post-operative Pain
- Trial name
- SMOOTH-SURG (NCT07539623)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Postoperative Pain, Cardiac Surgery
Comparison of Paravertebral Block and Deep Parasternal Intercostal Plane Block in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is often associated with significant postoperative pain. Poor pain control after sternotomy may increase opioid use, delay mobilization, prolong extubation time, and…
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Pain After Cardiac Surgery Via Median Sternotomy
- Trial name
- SPARE-CABG (NCT07498946)
- Testing
- Thoracic paravertebral block (TPVB), Bilateral Deep Parasternal Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Postoperative Pain, Sternotomy Pain
Comparison of Erector Spinae Plane Block (ESPB) With the Combination of Superficial Parasternal Intercostal Plane Block (SPIPB) and Serratus Anterior Plane Block (SAPB) in the Management of Postoperative Sternotomy Pain in Patients Undergoing Cardiac Surgery Via Sternotomy
This study aims to compare the effectiveness of two regional anesthesia techniques in managing pain for participants undergoing cardiac surgery via sternotomy.
- Conditions
- Postoperative Pain, Sternotomy Pain, Acute Pain, Cardiac Surgery
- Trial name
- NCT07472296
- Testing
- Erector spinae plane block (ESPB), Superficial Parasternal Intercostal Plane Block (SPIPB), Serratus Anterior Plane Block (SAPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Sternotomy Closure,Open Heart Surgery, Cardiac Surgery
Prediction of Chronic Pain in Cardiac Surgery: Evaluation by Algocartography Predict-ALGOCARTE
Sternotomy results in chronic postoperative pain in 30-55% of subjects. Few studies have been published on chronic pain in cardiac surgery, but there appears to be a relationship between the area of peri-scar hyperalgesia, which…
- Conditions
- Sternotomy Closure,Open Heart Surgery, Cardiac Surgery, Chronic Pain Post-Procedural
- Trial name
- Predict-ALGOCA (NCT06681272)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Sternotomy
Comparison of the Efficacy of Combined Transversus Thoracic Plane Block and Serratus Anterior Plane Block Versus Erector Spinae Plane Block in the Management of Sternotomy Pain
Background and Purpose: Median sternotomy is the standard surgical approach for cardiac procedures, yet it is associated with significant postoperative pain.
- Conditions
- Postoperative Pain, Sternotomy, Nerve Block, Patient Outcome Assessment
- Trial name
- NCT07452627
- Testing
- TTP Block, ESP Block, SAP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Uludag University
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Sternotomy
Chronic postoperative pain is a well-known problem. Chronic postoperative pain is defined as pain that begins following a surgical procedure and persists for more than 2 months without other obvious causes such as infection or…
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Sternotomy
- Trial name
- NCT05357963
- Testing
- Sternotomy application
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain, Sternotomy
Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is associated with significant intraoperative and postoperative pain, often requiring substantial opioid administration.
- Conditions
- Postoperative Pain, Sternotomy, Opioid Consumption, Intraoperative Pain Control
- Trial name
- NCT07315308
- Testing
- Deep Parasternal Intercostal Plane Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Heart Surgery Via Sternotomy, Post-operative Analgesia
Advantage of Tramadol in Local Analgesia Post-Sternotomy
Sternotomy, the reference approach for heart surgery, may induce profound and intense post-operative pain. One method of analgesia used is patient-controlled intravenous morphine.
- Trial name
- ATLAS (NCT02851394)
- Testing
- Levobupivacaine, tramadol
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Universitaire Dijon