Clinical trials: Spinal Manipulation
Cervicalgia
Effects of Cervical Spine Manipulation on Gait
The purpose of the study is to see if manipulation of the neck will change the way people who may or may not have neck pain, walk under differing conditions.
- Trial name
- NCT02287324
- Testing
- Manipulation, Manual Contact
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Trigger Points, Myofascial, Myofascial Trigger Points
Dose Response Effects of Cervical Spinal Manipulative Therapy (SMT) on Pressure Sensitivity of Myofascial Trigger Points
Specific Aim 1: To determine if the effect of cervical spinal manipulation on the pressure pain thresholds in a myofascial trigger point in the infraspinatus muscle can be enhanced and/or extended after a second cervical spine…
- Conditions
- Trigger Points, Myofascial, Myofascial Trigger Points, Myofascial Pain Syndrome
- Trial name
- NCT01418170
- Testing
- cervical spinal manipulative therapy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Canadian Memorial Chiropractic College
Vulvodynia, Perineal Pain
Effect of Spinal Manipulation on Vulvar Pain
The purpose of the study is to determine the effect of thoracic spine manipulation on vestibule pain as determined by sensory testing (q-tip and pressure algometry) in a group of women with provoked vestibulodynia (PVD).
- Conditions
- Vulvodynia, Perineal Pain, Vulvar Pain
- Trial name
- SpManipPP (NCT04016467)
- Testing
- Thoracic manipulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Mary Hardin-Baylor
Low Back Pain, Cervical Pain
Spinal Manipulation Effectiveness in Spinal Disorders
The aim of the present intervention study is to determine the effectiveness of manipulation techniques.
- Conditions
- Low Back Pain, Cervical Pain, Pain
- Trial name
- NCT03190187
- Testing
- Spinal Manipulation
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- DAVID CRUZ DÍAZ
Mechanical Neck Pain
Development of a Clinical Prediction Rulefor Neck Manipulation
Cervical spine manipulation has been shown to be helpful for some patients with neck pain. This study sought to determine factors which were predictive of which patients with neck pain would benefit from manipulation.
- Trial name
- NCT01620905
- Testing
- Manipulation
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Nevada, Las Vegas
Neck Pain Musculoskeletal, Neck Pain Treatment
Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief
Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging.
- Conditions
- Neck Pain Musculoskeletal, Neck Pain Treatment, Cervicalgia
- Trial name
- NCT06906107
- Testing
- Cervical Manipulation, Exercise, Mobilization
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Baylor University
Neck Pain
Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain
This study is designed to compare the short-term effects of two different thoracic spine thrust manipulation techniques on neck range-of-motion, pain, and self-reported disability in people with neck pain.
- Trial name
- NCT02245425
- Testing
- Supine Thoracic Spine Manipulation, Prone Thoracic Spine Manipulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- A.T. Still University of Health Sciences
Low Back Pain, Cervical Pain
Prospective Study of Post Surgical Continued Spinal Pain Patients
Continued spinal pain following spine surgery is reported in up to 50% of patients. Disability and pain following spine surgery occurs.
- Conditions
- Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder
- Trial name
- NCT05401682
- Testing
- Cox chiropractic care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Primary Dysmenorrhea, Dysmenorrhea
Spinal Manipulation For Menstrual Symptoms and Sleep in Individuals With Primary Dysmenorrhea
The goal of this observational study is to evaluate if spinal manipulation (SM) combined with connective tissue massage (CTM) improves pain, menstrual symptoms, depression levels, and sleep quality in women with primary…
- Trial name
- NCT06673537
- Testing
- Connective Tissue Massage (CTM), Spinal Manipulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Chronic Low-back Pain, Back Disorder
Movement Performance in Persons With Chronic Back Pain
The goal of this laboratory-based cross-over randomized controlled study is to study the immediate effects Spinal manipulative therapy (SMT) and exercise therapy (ET) compared to open-label placebo (OLP) on movement performance…
- Trial name
- NCT06891625
- Testing
- SMT, ET, OLP
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Acute Pain, Low Back Pain, Mechanical
Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain
This is a study of adults with acute low back pain flare-up at risk of becoming chronic and disabling. The study tests how well spinal manipulation and guided selfcare work compared to standard medical care.
- Trial name
- PACBACK (NCT03581123)
- Testing
- Supported-Self Management (SSM), Spinal Manipulation Therapy (SMT), SMT + SSM
- Where
- 3 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- University of Minnesota
Safety Issues
MIST3: Active Patient Safety Reporting
This study will seek to describe and understand adverse events (AE) severity ratings.
- Trial name
- MIST3 (NCT04161677)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Parker University
Neck Pain, Cervical Pain
The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain
The purpose of this research is to compare the effects of two commonly used, safe, thoracic spine grade 1-4 and grade 5 mobilization to the thoracic spine on cervical spine pain in individuals with nontraumatic cervical pain.
- Trial name
- NCT01760590
- Testing
- Manual Manipulation, Mobilization
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Keystone Rehabilitation Systems
Low Back Pain
Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients
The long-term goal for this study is to understand the physiological mechanisms of various forms of spinal manipulation in order to refine and improve this therapy for appropriately selected patients.
- Trial name
- D2P3 (NCT00830596)
- Testing
- HVLA-SM, LVVA-SM
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Palmer College of Chiropractic
Metabolic Syndrome
The Effects of Chiropractic in Adults With Metabolic Syndrome
The purpose of this study is to assess the feasibility of our study procedures/protocols and to look at the potential effects of chiropractic care on people with metabolic syndrome.
- Trial name
- MET (NCT05884437)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Life University
Low Back Pain
Assessing Patient Response to Therapeutic Exercise Based on Clinical Prediction Rule (CPR) for Spinal Manipulation
The purpose of this study is to determine whether patients who meet the criteria of the clinical prediction rule for spinal manipulation may respond more favorably to repeated exercises according to a direction of preference…
- Trial name
- NCT00916734
- Testing
- MDT (McKenzie Method), Spinal thrust manipulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Daemen College
Manipulation, Psychologic, Proprioception
Does Spinal Manipulation Therapy Impact Lumbar Proprioception
Spinal manipulation therapy (SMT) has long been a component of manual therapy and physical rehabilitation programs, especially as a modality for pain relief.
- Conditions
- Manipulation, Psychologic, Proprioception, Vibration; Exposure
- Trial name
- NCT04869514
- Testing
- spinal manipulation
- Where
- Switzerland
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Manipulation, Spinal
The Effect of a Single Spinal Manipulation on Cardiovascular Autonomic Activity
This study evaluates the effect of a single high-velocity low-amplitude spinal manipulation on both cardiovascular autonomic activity and pressure pain thresholds.
- Trial name
- NCT03273868
- Testing
- High velocity low amplitude manipulation
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Institut Franco Europeen de Chiropratique
Neuromuscular Subluxation of Joint, Manual Therapy
Immediate Effect of Cervical and Sacroiliac Manipulation on the Autonomic Nervous System and Balance
The aim of this study is to investigate the immediate effects of high-velocity low-amplitude (HVLA) chiropractic manipulation on the autonomic nervous system and baropodometric parameters.
- Conditions
- Neuromuscular Subluxation of Joint, Manual Therapy, Autonomic Nervous System Activity
- Trial name
- CSMPAANS (NCT06642688)
- Testing
- Sacroiliac Joint Manipulation, Cervical Spine Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Back Pain, Scoliosis
Back Pain and Spinal Manipulation in Adolescent Scoliosis
Adolescent idiopathic scoliosis (AIS) affects 2 - 3% of children and adolescents older than 10 years and is of unknown cause. It was initially thought that occurrences of back pain (BP) were similar to the one encounter in…
- Trial name
- NCT02609009
- Testing
- Spinal Manipulation Therapy, Usual Medical Care
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- St. Justine's Hospital