Clinical trials: Spinal Anaesthesia
Ceserean Section, Obstetric Quality of Recovery
Anesthetic Technique and Quality of Recovery After Cesarean Delivery
The goal of this prospective observational study is to evaluate whether the type of neuraxial anesthesia is associated with postoperative quality of recovery in adult women undergoing cesarean delivery.
- Conditions
- Ceserean Section, Obstetric Quality of Recovery, Neuraxial Anesthesia
- Trial name
- NCT07896733
- Testing
- Spinal anesthesia (heavy bupivacaine), epidural anesthesia, combine spinal epidural anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Marmara University
Obstetric
Analgesic Efficacy of Transvers Abdominis Plane Block and Transversalis Fascia Plane Block in Cesarean Section
This study was designed as a prospective, randomized observational clinical trial. A total of 90 adult women were included in the study performed elective cesarean section.
- Trial name
- NCT06386978
- Testing
- Transverse Facia Plane Block (TAP Block), Transversalis Facia Plane Block (TFP Block), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Vomiting
Hyoscine Butyl-bromide Versus Ondansetron for Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia
overall incidence of intraoperative nausea and vomiting(IONV) during regional anesthesia for cesarean section is extremely variable, up to 80 percent , depending on the anesthetic technique used (spinal, epidural or combined…
- Trial name
- NCT04785118
- Testing
- Hyoscine N Butylbromide, Ondansetron, Saline
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Assiut University
Perfusion Index, Position Differences
Evaluation Of The Effects Of Changes In Operating Table Position On Perfusion Index And Spinal Anesthesia
The aim of this observational study is to investigate how table position affects the development of block in patients undergoing spinal anesthesia. Perfusion index measurements will be used to answer this question.
- Trial name
- Perfusion (NCT07400185)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Enes Celik
Stress, Pain
Evaluation of the Surgical Pleth Index During Spinal and General Anesthesia
The Surgical Pleth index (SPI) has been introduced as a non invasive tool to "measure" stress and pain during surgery. Preliminary studies were performed in patients under general anaesthesia with propofol and remifentanil.
- Trial name
- NCT00789438
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- University Hospital Schleswig-Holstein
Anesthesia, Spinal, Arthroplasty, Replacement, Knee
Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty
The purpose of this study is to determine if a shorter-acting spinal anesthetic called mepivacaine has advantages over a longer-acting medication called bupivacaine.
- Conditions
- Anesthesia, Spinal, Arthroplasty, Replacement, Knee, Pain Management, Early Ambulation
- Trial name
- NCT02980926
- Testing
- Mepivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Femoral Neck Fractures, Nerve Block
Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery
Femoral neck fracture surgery in elderly patients is frequently complicated by intraoperative hypotension and inadequate postoperative analgesia.
- Trial name
- NCT07346885
- Testing
- Lumbar and Sacral Plexus Block, Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Pre-Eclampsia
Restrictive Fluid Therapy in Severe Preeclampsia
Introduction: Pre-eclampsia is a multifactorial syndrome which occurs in hypertension and proteinuria in pregnant women over 20 weeks gestation.
- Trial name
- NCT02214186
- Testing
- Restrictive Fluid Therapy
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Sedation; Aged; Hemodynamics
A Comparision of Midazolam-dexmedetomidine With Dexmedetomidine Alone for Hemodynamic Stability and Quality of Sedation in Elderly Patients Under Spinal Anesthesia
The purpose of this study is to compare midazolam-dexmedetomidine with dexmedetomidine alone for hemodynamic stability and quality of sedation in elderly patients under spinal anesthesia.
- Trial name
- NCT01979653
- Testing
- dexmedetomidine alone or dexmedetomidine + midazolam
- Where
- South Korea
- Sponsor
- Severance Hospital
Epidural Catheterization
Ultrasound Predictors of Difficulty in Performing Epidural Anesthesia for Labor in Pregnant Patients.
This is a prospective observational study conducted at the University Hospital of Padua. The goal is to identify ultrasound markers that can help predict whether placing an epidural catheter during labor will be difficult.
- Trial name
- NCT07056166
- Testing
- epidural catheter, spine ultrasonography
- Where
- Italy
- Volunteers
- 563 people
- Sponsor
- University of Padova
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Hypotension, Anesthesia, Spinal
Jugular Ultrasound for Spinal Hypotension
Spinal induced hypotension is common complication in geriatric group of patient with percentage up to 73% among these group]. the most common causes that enhance occurrence of post spinal anesthesia induced hypotension among…
- Conditions
- Hypotension, Anesthesia, Spinal, Aged
- Trial name
- JUSH (NCT07000188)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Hemorrhoid, Peri Anal Fistula
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl
In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl…
- Trial name
- NCT01880775
- Testing
- Prilocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Anesthesia, Spinal, Elderly
Influence Of Low Dose Intrathecal Naloxone On Bupivacaine - Fentanyl Spinal Anaesthesia For Lower Limb Orthopedic Surgery In Elderly Patients
Fentanyl is a safer alternative than morphine in the management of postoperative pain in elderly. However, pruritus, nausea and vomiting are unwanted side effects of intrathecal fentanyl administration, that can decrease patient…
- Trial name
- NCT04673812
- Testing
- Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Kasr El Aini Hospital
Spinal Anesthesia, Hemodynamic Changes
Hemodynamic Effects of Bilateral and Unilateral Spinal Anesthesia Using the Continuous Pressure Recording Analytical Method.
This randomized controlled study aims to compare the intraoperative hemodynamic effects of unilateral and bilateral spinal anesthesia in elderly patients undergoing elective total hip arthroplasty.
- Trial name
- NCT07789795
- Testing
- Unilateral Spinal Anesthesia, Bilateral Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Kayseri City Hospital
Arthroplasties, Knee Replacement, Nerve Block
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs.
- Conditions
- Arthroplasties, Knee Replacement, Nerve Block, Urinary Retention Postoperative, Anesthesia, Spinal
- Trial name
- POURRKA (NCT07050277)
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypotension, Ischemia
Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for preventing hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and for…
- Trial name
- NCT00421200
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 375 people
- Sponsor
- Sangart
Hypotension During Surgery
Electrical Acupoint Stimulation Reduces Intrathecal Anesthesia Induced Hypotension
The parturients may suffer from hypotension after spinal anesthesia and the incidence could be as high as 70-80% when pharmacological prophylaxis is not used.
- Trial name
- EARTH (NCT05724095)
- Testing
- high frequency acupoint stimulation, low frequency acupoint stimulation, electrodes attached
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Zhihong LU
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