Clinical trials: Speech Disorder
Tongue Neoplasms, Tongue Cancer
Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue
This study will fill a scientific gap in the current knowledge providing data for evaluation of the palatal augmentation prosthesis (PAP) as a therapeutic modality post-surgery.
- Conditions
- Tongue Neoplasms, Tongue Cancer, Oral Cancer
- Trial name
- PGSRT (NCT02584270)
- Testing
- Palatal Augmentation Prosthesis (PAP), Articulation Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Developmental Articulation Disorder, Speech Disorder
Characteristics of Idiopathic Familial Speech Disorders
According to studies, speech disorders with unknown causes (idiopathic) affect approximately 5% of the population at some point in their life.
- Conditions
- Developmental Articulation Disorder, Speech Disorder, Stuttering
- Trial name
- NCT00001551
- Where
- 2 sites in United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alzheimer Disease, Early Onset, Alzheimer Disease
Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks
This study attempts to identify two types of AD by using clinical and cognitive tasks and brain imaging. The subtypes of AD are separated into a "typical" group (memory loss) and a "variant" group (language, visuospatial, and…
- Conditions
- Alzheimer Disease, Early Onset, Alzheimer Disease, Alzheimer Disease, Late Onset, Dementia, Alzheimer Type
- Trial name
- EOAD-Subtype (NCT03153371)
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Aphasia, Stroke
Escitalopram and Language Intervention for Subacute Aphasia
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and…
- Trial name
- ELISA (NCT03843463)
- Testing
- Escitalopram 10mg, Computer-delivered naming treatment
- Where
- 3 sites in United States
- Volunteers
- 88 people
- Sponsor
- Johns Hopkins University
Any Disease Causing Death in the ICU or Within 24 Hours of Discharge From the ICU
Integrating Palliative and Critical Care (IPACC) Study
The purpose of this research study is to evaluate an intervention to improve the care given to patients who are dying in the intensive care unit (ICU) and their families.
- Trial name
- IPACC (NCT00685893)
- Testing
- Education, Local Champions, Institution Feedback
- Where
- 15 sites in United States
- Volunteers
- 3,498 people
- Sponsor
- University of Washington
Hearing Loss
Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System
To evaluate the performance of the Nucleus 5 Cochlear Implant System.
- Trial name
- NCT01072409
- Testing
- Nucleus 5 Cochlear implant, Cochlear implantation
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Cochlear
Cognition Disorder
Cognitive and Speech Disorders in Children With Congenital Heart Defects
The study is aimed to found out expressive speech disorders as a sign of neurocognitive development delay in children with congenital heart defects before and after surgery
- Trial name
- NCT06565299
- Testing
- Cardiovascular surgery with cardiopulmonary bypass
- Where
- Russia
- Volunteers
- 217 people
- Sponsor
- Kemerovo State Medical University
Stroke, Aphasia
Effects of rTMS Based on Brain Activation During Language Performance in Stroke Patients With Non-fluent Aphasia
The aim of this study is to assess the safety and clinical efficacy of high or low-frequency repetitive transcranial magnetic stimulation based on brain activation with functional near infrared spectroscopy in poststroke…
- Trial name
- NCT02556385
- Testing
- High frequency rTMS, Low frequency rTMS
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Bundang Hospital
Autism, Communication Disorders
iPad Application to Treat Prosodic Deficits in Students With Communication Disorders
The purpose of this study is to evaluate the utility of a specialized iPad application designed to treat difficulties with intonation (e.g., melody in voice) in children with autism spectrum disorders (ASD) and other…
- Trial name
- NCT01917864
- Testing
- iPad Application
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Yale University
Preterm Birth, Pain, Procedural
Maternal Speech Decreases Pain Scores and Increases Oxytocin Levels in Preterm Infants During Painful Procedures
Preterm infants undergo early separation from parents and are exposed to frequent painful clinical procedures, with resultant short- and long-term effects on their neurodevelopment.
- Trial name
- NCT04762004
- Testing
- Maternal speech, Maternal singing, Standard care
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Geneva, Switzerland
Hearing Impaired
Effects of Stimulus Validity on Speech Recognition
The effects of talker variability will be investigated with four groups of listeners (young normal-hearing; old normal-hearing; young hearing-impaired; old hearing-impaired).
- Trial name
- NCT00013364
- Testing
- Talker variability
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- US Department of Veterans Affairs
Autism, Autism Spectrum Disorder
Word Learning From Parentese in Autistic Children
The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are…
- Conditions
- Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
- Trial name
- NCT06649916
- Testing
- Parentese Speech, Adult Registered Speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Stroke, Aphasia
Adjustment With Aphasia After Stroke: SUPERB
Aims: This exploratory trial will: 1. Explore the feasibility of a definitive/phase III RCT on clinical and cost-effectiveness of peer-befriending for people with aphasia post-stroke. 2.
- Trial name
- SUPERB (NCT02947776)
- Testing
- PEER, USUAL
- Where
- 5 sites in United Kingdom
- Volunteers
- 62 people
- Sponsor
- City, University of London
Parkinson Disease
A Novel Measurement Concept to Objectively Quantify Severity of Vocal and Speech Related Symptoms Associated With Parkinson's Disease
The aim of this research program is to develop and validate a smartphone app-based digital measurement concept that: Objectively quantifies the severity of Parkinson's Disease (PD) related vocal and speech symptoms; Accurately…
- Trial name
- Voice-PD (NCT05421832)
- Testing
- Digital Speech Application
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Speech Sound Disorder
Beatboxing and Residual Speech Errors
This project will study the effect of practicing speech sounds via beatboxing on speech accuracy, engagement in therapy, and functional outcomes for older children and adolescents with speech sound disorders (SSDs).
- Trial name
- NCT03972449
- Testing
- BEAT-Speech, Traditional Articulation Approach
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duquesne University
Stroke, Aphasia
Studying Language With Brain Stimulation in Aphasia
The overall goal of this study is to evaluate whether stimulation of two brain areas alongside behavioral speech-language therapy increases connectivity to improve language functions in stroke-aphasia patients.
- Trial name
- NCT05660304
- Testing
- Cortico-cortical paired associative stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Primary Progressive Aphasia
Stimulating the Aging Brain Using Brain and Sensory Stimulation
The goal of this project is to investigate whether transcranial electrical stimulation and sensory stimulation affect language outcomes in individuals with primary progressive aphasia (PPA).
- Trial name
- StAB (NCT07650188)
- Testing
- tACS or multisensory stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Aphasia, Stroke
Study of the Effect of Transcranial Stimulations in Aphasic Subject Within a Year of Their Stroke
The aim of this work is to study the effect of transcranial direct current stimulation combined with naming therapy in acute and post-acute stroke comparing four bihemispheric positioning electrodes to a sham condition.
- Trial name
- NCT02101398
- Testing
- eldith DC-stimulator, configuration F7A, eldith DC-stimulator, configuration F7C, eldith DC-stimulator, configuration T5A
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Hearing Loss, Speech and Language Development Delay Due to Hearing Loss
Teletherapy in Children Who Are Deaf and Hard of Hearing
This study seeks to determine the effectiveness of speech/language teletherapy to address disparities in speech and language outcomes in children who are deaf or hard-of-hearing (D/HH).
- Trial name
- NCT04928209
- Testing
- Speech-Language Teletherapy
- Where
- 5 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of California, San Francisco
Right Hemispheric Stroke
Functional Connectivity and Predictors of Affective Aprosodia Intervention in Subacute Right Hemisphere Stroke
This study is an investigation of a behavioral speech and language treatment for emotional prosody recognition and production deficits in subacute right hemisphere stroke.
- Trial name
- NCT04575909
- Testing
- Aprosodia Intervention, No-Intervention
- Where
- United States
- Sponsor
- Johns Hopkins University
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