Clinical trials: Spasticity, Muscle
Stroke
The Effect Of Transcranial Magnetic Stimulation In Patients With Stroke
This study is aimed to investigate the effect of continuous theta burst stimulation (cTBS) and low frequency repetitive transcranial magnetic stimulation (rTMS) on upper extremity spasticity and functional recovery in patients…
- Trial name
- NCT04562415
- Testing
- Active Repetitive Transcranial Magnetic Stimulation Therapy, Active Continuous Theta Burst Stimulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Upper Limb Spasticity
A Clinical Study to Evaluate the Safety and Efficacy of JHM03 in Adult Patients With Upper Limb Spasticity
This is a phase Ib/II clinical study to evaluate the safety and efficacy of recombinant botulinum toxin type A（JHM03）in adult patients with upper limb spasticity.
- Trial name
- NCT06584240
- Testing
- Sequence 1, Sequence 2, Sequence 3
- Where
- 20 sites in China
- Volunteers
- 84 people
- Sponsor
- JHM BioPharma (Tonghua) Co. , Ltd.
Spinal Cord Injury
Effects of Marijuana on Neuropathic Pain and Spasticity in Spinal Cord Injury Patients
The goal of this clinical trial is to compare effects of marijuana or cannabis on neuropathic pain and spasticity in spinal cord injury patients.
- Trial name
- NCT06190470
- Testing
- Cannabis
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Khon Kaen University
Cerebral Palsy, Spastic
Effect of the Nutritional Support System on Neuromotor Alterations in Patients With Cerebral Palsy
Study to determine the impact of a nutritional support system (NSS) on neuromotor alterations in patients with cerebral palsy.
- Conditions
- Cerebral Palsy, Spastic, Malnutrition
- Trial name
- NSS-PC (NCT05648422)
- Testing
- Probiotics, NSS Nutritional Support System, Deworming
- Where
- Mexico
- Volunteers
- 144 people
- Sponsor
- Anahuac University
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Stroke Sequelae, Spasticity, Muscle
Effects of CRet Associated With Functional Massage (F.M) on Gait and Functionality in Post-stroke Spasticity
The purpose of this study is to assess the immediate effects of CRet associated to Functional Massage (F.M) in terms of gait and functionality after stroke
- Conditions
- Stroke Sequelae, Spasticity, Muscle, Massage, Electrotherapy
- Trial name
- NCT04851756
- Testing
- CRet
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Internacional de Catalunya
Hyperhidrosis, Muscle Spasticity
Safety and Efficacy of BOTOX® (Botulinum Toxin Type A) in Korea
This post marketing surveillance study in Korea will evaluate the safety and efficacy of BOTOX (botulinum toxin Type A) in patients who receive treatment according to standard of care for primary axillary hyperhidrosis, focal…
- Conditions
- Hyperhidrosis, Muscle Spasticity, Glabellar Lines
- Trial name
- NCT02043145
- Testing
- botulinum toxin Type A
- Where
- South Korea
- Volunteers
- 727 people
- Sponsor
- Allergan
Spasticity, Muscle
Obturator Cryoneurotomy for Hip Adductor Spasticity
The purpose of the study is to measure the effects of obturator nerve cryoneurotomy, on clinical measures in adult (ages 19+) and paediatric (ages 12-18) patients with hip adductor spasticity, who will receive this procedure as a…
- Trial name
- NCT05147441
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Vancouver Island Health Authority
Stroke, Spasticity as Sequela of Stroke
Dynamic Lycra Orthosis as an Adjunct to Botulinum Toxin-A Injection for Post-stroke Spasticity
Upper extremity splints are one of the nonpharmacologic treatments used to treat hypertonicity after stroke. The purpose of splinting is to support, to position, to immobilize, to prevent contracture and deformities, to reduce…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Upper Limb Hypertonia
- Trial name
- NCT03546959
- Testing
- Lycra sleeve, Rehabilitation, Botulinum Toxin
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Marmara University
Stroke
Neurodynamics on Spasticity in Upper Extremity of Stroke Patients.
Data will be collected from 40 patients with hemiplegia, caused by stroke from DHQ hospital Jhelum. its an RCT Neurodynamics with conventional treatment to experimental group and conventional treatment alone to control group will…
- Trial name
- NCT03822923
- Testing
- Experimental group, Control group
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Riphah International University
Lower Limb and Combined Lower Limb and Upper Limb Spasticity Due to Cerebral Palsy
Long-term Open-label Study of Botulinumtoxin Type A to Treat Spasticity of Leg(s) or Leg(s) and Arm in Cerebral Palsy
The purpose of this study is to determine whether injections of Botulinum toxin type A into muscles of the leg(s) or of leg(s) and one arm are safe in treating children/adolescents (age 2-17 years) long-term with increased muscle…
- Trial name
- NCT01905683
- Testing
- IncobotulinumtoxinA (16-20 Units per kg body weight)
- Where
- 43 sites in Austria, Czechia and 10 more
- Volunteers
- 370 people
- Sponsor
- Merz Pharmaceuticals GmbH
Spasticity as Sequela of Stroke
Phenol and Botulinum Toxin vs Botulinum Toxin Alone for Post-Stroke Upper-Limb Spasticity
This study aims to evaluate the efficacy of a combined treatment approach for post-stroke upper limb spasticity using phenol neurolysis and botulinum toxin (BoNT).
- Trial name
- NCT07440173
- Testing
- phenol neurolysis, Botulinum Toxin - A injections
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cerebral Palsy, Spasticity
Dutch National ITB Study in Children With Cerebral Palsy
The objective of this study is to determine the efficacy and safety of treatment with intrathecal baclofen for severe spasticity in children with cerebral palsy.
- Trial name
- NCT00367068
- Testing
- baclofen, intrathecal, infusion pump for intrathecal baclofen, Synchromed, Medtronic
- Where
- Netherlands
- Volunteers
- 18 people
- Sponsor
- Maastricht University
Spastic Hemiplegic Cerebral Palsy
Effectiveness of Modified Constraint-Induced Movement Therapy Versus Mirror Therapy in Spastic Hemiplegic Cerebral Palsy Children
This randomized controlled trial was conducted to compare the effectiveness of Modified Constraint-Induced Movement Therapy (MCIMT) and Mirror Therapy in improving upper limb function among children with spastic hemiplegic…
- Trial name
- NCT07747974
- Testing
- Experimental, Control
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Ibadat International University, Islamabad
Chronic Stroke
Neural Mobilization With Task Based Activities on Upper Limb in Patients With Chronic Stroke.
Stroke is defined as sudden neurological disruption of blood supply to brain. It is most common disease that causes severe disabilities like hemiparesis which is most common motor impairment that leads to persistent upper limb…
- Trial name
- NCT06131827
- Testing
- Neural mobilization, Task based activities
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Hemiplegia, Spastic
The Use of Ultrasound for Botulinum Toxin Subscapularis Muscle Injection Guidance in Spastic Hemiplegic Shoulder Pain
The aim of the study is to describe the efficacy of a new approach to the subscapularis muscle under US guidance for the injection of botulinum toxin in patients that underwent a stroke suffering from hemiplegic shoulder pain.
- Trial name
- NCT03621423
- Testing
- ultrasound guided injection
- Volunteers
- 30 people
- Sponsor
- Loewenstein Hospital
Stroke
Early Treatment of Post-stroke Spasticity With Botulinum Toxin
This was a multicentric observational study with the aim to evaluate the effect of early treatment with botulinum toxin type A (BoNT-A) on post-stroke spasticity in adult patients.
- Trial name
- BTX_ST-ITA14 (NCT04404868)
- Testing
- Normal clinical practice
- Where
- Italy
- Volunteers
- 86 people
- Sponsor
- Universita di Verona
Stroke, Spastic Hemiplegia
The Effects of Neurorehabilitation Approaches Involving Different Upper Extremity Reactive Trainings in Stroke Patients
The goal of this clinical trial is to investigate the effectiveness of upper extremity training, which is expected for 5 seconds on the target during reaching forward, and to compare the effectiveness of neurorehabilitation…
- Trial name
- NCT06086314
- Testing
- reactive exercise training with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program, reactive exercise training with co-contraction with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program., neurorehabilitation program with functional reaching training without device.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Spasticity, Multiple Sclerosis
A Study of the Safety and Effectiveness of Sativex®, for the Relief of Symptoms of Spasticity in Subjects, From Phase B, With Multiple Sclerosis (MS)
The purpose of this study is to determine whether Sativex® versus Placebo is effective in the relief of symptoms of spasticity in subjects with multiple sclerosis, who have been identified as having a capacity to respond to…
- Trial name
- NCT00681538
- Testing
- Sativex®
- Where
- United Kingdom
- Volunteers
- 572 people
- Sponsor
- Jazz Pharmaceuticals
Spinal Cord Injuries, Muscle Spasticity
Cyproheptadine and Chlorpromazine Effects on Spasticity
The main goal of this research is to understand the neuronal mechanisms that mediate the development of spasticity and motor dysfunction after spinal cord injury.
- Trial name
- NCT01509885
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta