Clinical trials: Somatic Symptom Disorder
Somatoform Disorders, Globus Hystericus
Treatment of Globus Sensations With Psychotherapy
The purpose of this study is to determine whether psychotherapy (based on exposure techniques) is effective in the treatment of functional somatic symptoms (FSS)/Somatoform Disorders (as exemplified here in subjects with globus…
- Trial name
- NCT01590992
- Testing
- Exposure-based psychotherapy for somatic symptoms, Relaxation therapy
- Where
- Switzerland
- Volunteers
- 175 people
- Sponsor
- University Hospital, Basel, Switzerland
Neuropathic Pain, Depression
The Effect of Diet on Chronic Inflammation and Related Disorders Following Spinal Cord Injury
Spinal cord Injury (SCI) is a condition commonly associated with a state of chronic low-grade inflammation due to a variety of factors such heightened risk for infection and development of metabolic disorders.
- Conditions
- Neuropathic Pain, Depression, Cognitive Impairment, Somatic Neuropathy
- Trial name
- NCT02099890
- Testing
- Omega-3, Vegetation Protein Powder, InflanNox
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brock University
Depression - Major Depressive Disorder, Generalized Anxiety Disorder
Ultra-brief Psychological Treatments for Emotional Symptoms and Disorders
The main objective of this randomized clinical trial is to study if various modalities of brief (eight sessions) and ultra-brief (four sessions) transdiagnostic cognitive-behavioral treatment work for decrease emotional symptoms…
- Conditions
- Depression - Major Depressive Disorder, Generalized Anxiety Disorder, Generalized Anxiety, Anxiety
- Trial name
- UltraPsyBrief (NCT06909669)
- Testing
- Group ultra-brief transdiagnostic cognitive-behavioral therapy, Group brief transdiagnostic cognitive-behavioral therapy, Individual ultra-brief transdiagnostic cognitive-behavioral therapy
- Where
- 2 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Universidad de Córdoba
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Somatic Symptom Disorder
Effects of COVID-19 Forced Isolation Context on Adolescents With and Without Somatic Symptom Disorder
The purpose of this study is to evaluate whether a forced isolation context (such provided by the ongoing Covid-19 pandemic restrictive measures) could reduce the burden of somatic symptoms among a group of patients with Somatic…
- Trial name
- NCT05795803
- Testing
- Forced isolation context
- Where
- Italy
- Volunteers
- 115 people
- Sponsor
- IRCCS Burlo Garofolo
Paraganglioma, Pheochromocytoma
Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study
Phaeochromocytomas and paragangliomas (PPGLs) are tumours of the adrenal medulla and extra-adrenal sympathetic nervous system, some which can become metastatic. It is a very rare disease and the tumours are often detected late.
- Conditions
- Paraganglioma, Pheochromocytoma, Genetic Predisposition to Disease, Pathology
- Trial name
- PPGL-Pred (NCT04788927)
- Where
- 2 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders
Exposure Therapy for Reactivity to Symptoms
It is unclear to what degree systematic exposure exercises contribute to the overall effects of exposure therapy (exposure and response prevention).
- Conditions
- Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders, Bodily Distress Disorder
- Trial name
- SOMEX2 (NCT07757854)
- Testing
- Planned, systematic, exposure exercises, Response prevention
- Where
- Sweden
- Volunteers
- 360 people
- Sponsor
- Region Stockholm
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Severe Health Anxiety, Somatic Symptom Disorder
Cognitive Behavior Therapy for Health Anxiety: A Comparison of Three Forms of Self-help
Background Severe health anxiety, Somatic symptom disorder or Illness anxiety disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5), is associated with considerable personal distress…
- Conditions
- Severe Health Anxiety, Somatic Symptom Disorder, Illness Anxiety Disorder
- Trial name
- NCT01966705
- Testing
- Cognitive Behavior Therapy, exposure and response prevention (Internet, guided), Cognitive Behavior Therapy, exposure and response prevention (Internet, unguided), Cognitive Behavior Therapy, exposure and response prevention (Book, unguided)
- Where
- Sweden
- Volunteers
- 132 people
- Sponsor
- Karolinska Institutet
Low Back Pain, Posttraumatic Stress Disorder
Low Back Pain and Comorbid Posttraumatic Stress Disorder
The aim is to test whether the psychotherapeutic intervention Somatic Experiencing targeting Post Traumatic Stress Disorder (PTSD) symptoms will have an additional positive effect on the outcomes of guided physiotherapy against…
- Trial name
- NCT03244046
- Testing
- Psychotherapy, Physiotherapy
- Volunteers
- 140 people
- Sponsor
- University of Southern Denmark
Acinar Cell Carcinoma, Adenoid Cystic Carcinoma
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
This phase II trial studies nivolumab and ipilimumab in treating patients with rare tumors. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may…
- Conditions
- Acinar Cell Carcinoma, Adenoid Cystic Carcinoma, Adrenal Cortical Carcinoma, Adrenal Gland Pheochromocytoma
- Trial name
- NCT02834013
- Testing
- Biospecimen Collection, Computed Tomography, Echocardiography Test
- Where
- 1,007 sites in United States, Guam
- Volunteers
- 798 people
- Sponsor
- National Cancer Institute (NCI)
Somatic Symptom Disorder (DSM-V)
Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder
Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning.
- Trial name
- NCT06803485
- Testing
- Venlafaxine, Dosulepin
- Where
- India
- Volunteers
- 84 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Somatization Disorder, Functional Disorders
Mindfulness-based Cognitive Therapy for Patients With Functional Disorders
The aim of the study is to examine the efficacy of Mindfulness-Based Cognitive Therapy (MBCT) in patients with functional disorders defined as severe Bodily Distress Disorder.
- Conditions
- Somatization Disorder, Functional Disorders, Bodily Distress Disorder
- Trial name
- NCT00497185
- Testing
- Mindfulness-Based Cognitive Therapy for Functional Disorders
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Aarhus
Somatic Symptom Disorder
Use Repetitive Transcranial Magnetic Stimulation to Treat Somatic Symptom Disorder
This is a randomized double-blind sham-controlled crossover study; the interventions are high-frequency rTMS stimulation on left DLPFC and sham control. The study population is the patient with somatic symptom disorder.
- Trial name
- NCT05161819
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Somatization Disorder
Assessment of Somatic Symptom Burden
The Patient Health Questionnaire-15 (PHQ-15) is a frequently used questionnaire to assess somatic symptom burden. The Somatic Symptom Scale China (SSS-CN) was recently developed as a comprehensive self-report instrument in…
- Trial name
- NCT03321409
- Testing
- The general population, Patients with suspected CAD
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Patients, Anxiety Disorders
LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders
Background: Lysergic acid diethylamide (LSD) was extensively investigated in humans in the 1950s and 1960s. Particularly, LSD attenuated anxiety in patients with cancer.
- Trial name
- LSD-assist (NCT03153579)
- Testing
- LSD
- Where
- 2 sites in Switzerland
- Volunteers
- 46 people
- Sponsor
- University Hospital, Basel, Switzerland
Tinnitus, Acoustic Stimulation
Different Stimuli Were Given to Patients With Chronic Pure Tone Tinnitus to Verify the Effective Treatment of Tinnitus.
In this experiment, patients with chronic pure tone tinnitus were divided into three groups to receive auditory stimulation, somatosensory stimulation, vestibular stimulation and combined stimulation, in order to find an…
- Conditions
- Tinnitus, Acoustic Stimulation, Somatic Stimulation, Vestibular Stimulation
- Trial name
- NCT04118907
- Testing
- multiple sensory stimulation
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Dan Su
Somatic Symptom Disorder (DSM-V)
Cognitive-Behavioral Therapy Enriched With Emotion Regulation Training for Multiple Somatoform Symptoms
The purpose of this study is to evaluate whether cognitive-behavioral therapy enriched with strategies from emotion regulation training leads to better improvement in somatic symptoms and comorbid problems than…
- Trial name
- ENCERT (NCT01908855)
- Testing
- Cognitive-behavioral therapy + emotion regulation training for patients with multiple somatoform symptoms, Cognitive-behavioral therapy for patients with multiple somatoform symptoms
- Where
- 7 sites in Germany
- Volunteers
- 255 people
- Sponsor
- Philipps University Marburg
Hyperacusis
Exploratory Study on the Role of Somatic Modulation in Hyperacusis
This study focuses on patients with a primary complaint of hyperacusis. Hyperacusis has been defined as 'abnormally reduced tolerance to sound' and is commonly associated with tinnitus.
- Trial name
- NCT04693819
- Testing
- Somatic modulation
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- University Hospital, Antwerp