Clinical trials: Soft Tissue Healing
Dental Implants, Wound Healing
Effect of Different Suture Techniques on Early Healing of Peri-implant Soft Tissue
The purposes of this study are to compare the blood perfusion and early healing of horizontal mattress suture with vertical mattress sutures following open-flap implant surgery.
- Conditions
- Dental Implants, Wound Healing, Sutures
- Trial name
- NCT05289635
- Testing
- different suture types
- Volunteers
- 20 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Soft Tissue Injuries
Evaluation of the Effects of Four Different Flap Designs on Tissue Healing in Lower Third Molar Surgery
The aim of this study is to prospectively evaluate the effectiveness of 4 different flap types used during mandibular impacted wisdom teeth surgery on postoperative quality of life, soft tissue and hard tissue healing at the end…
- Trial name
- NCT06266052
- Testing
- Triangular Flap, Berwick Flap, Saurez Flap
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Dimensional Alterations
Dimensional Soft and Hard Tissue Alterations Following Single Tooth Extraction in the Anterior Maxilla - A Prospective Clinical Study
Bone modeling after tooth extraction has a major consequence on implant therapy, in particular in the esthetic zone. In esthetic sites, no tissue loss should occur if an optimal esthetic outcome is expected.
- Trial name
- Alterations (NCT02403700)
- Testing
- Cone beam computed tomography (CBCT)
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pressure Ulcers, Venous Ulcers
Use of Fish Skin Extracellular Matrix (ECM) to Facilitate Chronic Wound Healing
The clinical study is designed to assess the effectiveness, safety and non-immunogenicity of fish skin wound dressing extracellular matrix (ECM) in treating chronic wounds.
- Conditions
- Pressure Ulcers, Venous Ulcers, Diabetic Ulcers, Chronic Ulcer of Foot
- Trial name
- NCT01348581
- Testing
- Marigen Wound Dressing
- Where
- Iceland
- Volunteers
- 37 people
- Sponsor
- Kerecis Ltd.
Edentulous
Implant Placement With Simultaneous Gum Grafting
This study is a comparison of implant placed and simultaneously grafted with either autogenous connective tissue or a connective tissue allograft.
- Trial name
- NCT01431144
- Testing
- connective tissue autograft, connective tissue allograft
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Acute Radiation Dermatitis, Head and Neck Cancer (H&N)
Effectiveness of 0.9% Normal Saline Soaking in Managing Acute Radiation Dermatitis
The goal of this clinical trial is to learn if normal saline soaks can reduce the severity of acute radiation dermatitis in patients with sarcomas or head and neck cancer receiving radiotherapy.
- Conditions
- Acute Radiation Dermatitis, Head and Neck Cancer (H&N), Sarcomas
- Trial name
- NCT07553260
- Testing
- Normal Saline Soaks (0.9% Sodium Chloride)
- Where
- Jordan
- Volunteers
- 150 people
- Sponsor
- King Hussein Cancer Center
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Gingival Recession
Safety and Efficacy of Gintuit(TM)for Oral Soft Tissue Regeneration
The purpose of this study is to evaluate Gintuit as a safe and effective alternative to palatal tissue in the treatment of subjects (with recession-type defects) who have an insufficient zone of attached gingiva associated with…
- Trial name
- NCT00587834
- Testing
- Gintuit, Autologous palatal tissue
- Where
- 4 sites in United States
- Volunteers
- 96 people
- Sponsor
- Organogenesis
Tooth Extraction Status Nos, Tooth Fracture
The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh
The study will be conducted on 30 patients with split mouth design patients will be divided into curcumin and PRF groups patients will have bilateral tooth extraction one side will receive curcumin/PRF and the other side will be…
- Trial name
- NCT05816707
- Testing
- PRF, Curcuma Longa gel, extraction socket
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rania Farouk Mohamed Abdulmaguid
Hearing Loss - Conductive
Stability of the Cochlear Baha BI300/BA400 Implant System Loaded From 1 Week Post-surgery
Objectives To evaluate the safety of processor loading of the Cochlear BI300/BA400 implant system 1 week after implantation To evaluate the short term soft tissue healing and the long term skin reaction, with the new Cochlear…
- Trial name
- NCT02096809
- Testing
- One week loading of Bone Anchored Hearing Aid (BAHA), Cochlear Baha BI300/BA400 Implant System
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Aarhus University Hospital
Soft Tissue Healing
Peri-implant Soft Tissue and Bone Evaluation in Fully Computer Guided Immediate Implants
Prospective evaluation of perimplant soft tissue and bone response to one abutment one-time concept versus provisional abutment in fully guided single immediate implant placement.
- Trial name
- randomised (NCT06733870)
- Testing
- guided immediate implant surgery
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Implant
Healing Outcomes of Peri-implant Soft Tissues With Different Healing Abutments
The purpose of this study is to compare how well our research participants heal with two different kind of healing abutments used.
- Trial name
- NCT07249242
- Testing
- Healing Abutment- customized, Healing Abutment- pre fabricated
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Tufts University
Healing Surgical Wounds
Platelet Rich Fibrin in Soft Tissue Healing After Implant Uncovering
This study represents a prospective, controlled and randomized clinical trial assessing the effects of L-PRF on the healing time of the donor area and on the patient's postoperative morbidity in the 4 weeks following the Apically…
- Trial name
- NCT05375357
- Testing
- Application of L-PRF on the donor area, Secondary intention healing of the donor area
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Pain, Postoperative, Wound Heal
Clinical Efficacy of Soft Tissue Trimmer in Cases of Gingival Hyperplasia.
Postoperative pain and wound healing are compared after using conventional scalpel technique in comparison with the intervention which is using Soft tissue Trimmer for cases of gingival hyperplasia.
- Conditions
- Pain, Postoperative, Wound Heal, Gingival Hyperplasia
- Trial name
- NCT04542486
- Testing
- Excision of gingival hyperplasia using "Soft tissue trimmer "., Excision of gingival hyperplasia using the conventional scalpel technique
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Wound; Head, Multiple, Wound; Head, Scalp
Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection
- Trial name
- FTFDT3 (NCT03872544)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Dental Implants, Immediate Implant Soft Tissue Healing
Effectiveness of ALB-PRF With Two Types of Bone Grafts With Putty Form Around Immediate Dental Implants.
The goals of this clinical trial study is to evaluate the additive effect, of using ALB-PRF membrane combined with two different types of bone grafts with putty form in treatment of peri-implant bony defects around immediate…
- Conditions
- Dental Implants, Immediate Implant Soft Tissue Healing, Immediate Implant With Bone Graft
- Trial name
- ALB-PRFE-PRF (NCT06643468)
- Testing
- participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and collagen membrane., participants will receive immediate implant with nano-crystalline putty hydroxyapatite as bone graft and ALB- PRF as membrane., participants will receive immediate implant with beta-tricalcium phosphate + calcium sulphate bone graft and collagen membrane.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Platelet-rich Fibrin
Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to…
- Trial name
- NCT05866965
- Testing
- PRF, standard third molar surgical removal
- Where
- Vietnam
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lam Cu Phong
Dupuytren's Contracture
Evaluation of the Efficiency of Autologous Platelet Gel (Platelet Rich Fibrin) Obtained From Own Patients' Blood Versus Vaselitulle in Dupuytren's Disease Postoperative Wound Healing
This study is a clinical, multicentric, randomised open trial. The objective is to evaluate the efficiency, in terms of wound healing speed, of peroperative application of autologous platelets gel versus standardized wound…
- Trial name
- NCT00931567
- Testing
- Autologous platelets gel, Vaselitulle
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nice