Clinical trials: Sodium Bicarbonate
Hepatic Ischemia
Application of Sodium Bicarbonate Ringer's Solution in Laparoscopic Hepatectomy
Compared the effects of Sodium bicarbonate Ringer's solution and lactate Ringer's solution on the internal environment and hemodynamics of patients during laparoscopic liver resection, to observe the application prospect of…
- Trial name
- NCT05830136
- Testing
- sodium bicarbonate Ringer's solution
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Health Adults
Sodium Bicarbonate Solution Enhances Lens Cleanliness in Magnetically Controlled Capsule Endoscopy
Magnetically controlled capsule endoscopy (MCE) is a noninvasive alternative to conventional gastroscopy with comparable diagnostic accuracy.
- Trial name
- NCT07877506
- Testing
- Sodium Bicarbonate Solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Upper Gastrointestinal Bleeding
Safety & Efficacy of Omeprazole Sodium Bicarbonate for the Prevention of Upper GI Bleeding in the Critically Ill
Critically ill patients are at an increased risk of having upper gastrointestinal (GI) bleeding due to stress related mucosal damage.
- Trial name
- NCT00045799
- Testing
- Omeprazole sodium bicarbonate immediate release PWD/FS, Cimetidine IV
- Where
- 58 sites in United States
- Volunteers
- 354 people
- Sponsor
- Bausch Health Americas, Inc.
Healthy
Comparative Evaluation of the Effect on Blood Pressure of an Equivalent Content of Sodium in the Form of Bicarbonate of Sodium and in the Form of Sodium Chloride, on "Sensitive Sodium" Subjects
Many large-scale epidemiological studies have established a link between the average consumption of table salt (sodium chloride) and blood pressure.
- Trial name
- SODIVASC (NCT02561325)
- Testing
- Sodium Bicarbonate and Sodium chloride
- Where
- France
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Fluid Retention, Sodium Retention
The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress
The primary purpose of the proposed study is to evaluate the effects of a topical sodium bicarbonate lotion (PR Lotion, AMP Human, Park City, UT) on measures of hydration status and fluid balance in humans when exposed to the…
- Conditions
- Fluid Retention, Sodium Retention, Heat Stress, Dehydration (Physiology)
- Trial name
- AMP2 (NCT05092854)
- Testing
- PR Lotion - AMP Human Performance, AminoVital - Rapid Recovery
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Contrast Induced Nephropathy
Comparison Between Effect of Acetazolamide and NaHco3 in Prevention of Contrast Nephropathy
The purpose of this study is whether Acetazolamide is effective in prevention of contrast nephropathy
- Trial name
- NCT00634491
- Testing
- sodium bicarbonate, Acetazolamide, normal salin
- Where
- Iran
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Uric Acid Stones
Impact of Sodium Bicarbonate on 24-hour Urine Parameters in Hypocitriuric and Uric Acid Stone Formers
The incidence of kidney stone disease continues to rise globally. Although the treatment of kidney stone disease has dramatically improved in recent years, surgical management remains invasive and expensive.
- Trial name
- NCT06335537
- Testing
- Potassium citrate, Sodium bicarbonate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Irvine
Chronic Renal Failure
Effect of Hydration With Sodium Bicarbonate for Long-Term Clinical Outcomes in Patients With Chronic Kidney Disease Undergoing an Emergent Coronary Procedure
This study is to evaluate the efficacy of sodium bicarbonate plus N-acetylcysteine for the prevention of contrast-induced nephropathy.
- Trial name
- NCT00716001
- Testing
- N-acetylcysteine
- Sponsor
- Osaka General Medical Center
Sudden Cardiac Arrest
Sodium Bicarbonate in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrests (OHCA) account for over 60% of deaths from coronary artery disease. The annual incidence of OHCA treated by Emergency Medical Systems (EMS) is 41-89 per 100,000 population.
- Trial name
- SB CAT (NCT01377337)
- Testing
- sodium bicarbonate
- Where
- 2 sites in Israel
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Oral Mucositis
Effect of Black Mulberry Lollipop on Prevention of Oral Mucositis in Children
THE EFFECT OF BLACK MULBERRY LOLLIPOP AND SODIUM BICARBONATE USED IN ORAL CARE ON PREVENTION OF ORAL MUCOSITIS AMONG CHILDREN RECEIVING CHEMOTHERAPY DUE TO CANCER
- Trial name
- NCT04800549
- Testing
- Oral Mucositis
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Sapanca Ilce Devlet Hastanesi
Acute Kidney Failure
Clinical Trial of Sodium Bicarbonate to Prevent Contrast-Induced Nephropathy
The purpose of this study is to determine whether sodium bicarbonate is effective in the prevention of sodium-induced nephropathy
- Trial name
- NCT00424320
- Testing
- Sodium bicarbonate
- Where
- 2 sites in Mexico
- Volunteers
- 100 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS)
The Feasibility of Pulmonary Perfusion Assessment Using Sodium Bicarbonate Contrast With Electrical Impedance Tomography: A Prospective Pilot Study
The goal of this observational pilot study is to learn if sodium bicarbonate can be used safely and effectively as a contrast agent to map lung blood flow using electrical impedance tomography (EIT) in adults on mechanical…
- Conditions
- Acute Respiratory Failure, Acute Respiratory Distress Syndrome (ARDS), Pneumonia, Critical Illness
- Trial name
- NCT07542366
- Where
- China
- Volunteers
- 41 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Cholecystectomy, Laparoscopic, Ambulatory Surgical Procedures
Efficacy and Safety of Cocktail of Ropivacaine for Local Infiltration Analgesia in Patients Undergoing Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if the use of cocktail of ropivacaine,sodium bicarbonate and dexamethasone for incision local infiltration analgesia in patients undergoing ambulatory laparoscopic cholecystectomy is…
- Conditions
- Cholecystectomy, Laparoscopic, Ambulatory Surgical Procedures, Multimodal Analgesia
- Trial name
- NCT06819748
- Testing
- The cocktail of 0.5% ropivacaine ,5%sodium bicarbonate and 10 mg dexamethasone, 0.5% ropivacaine
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Heartburn
Comparison of Two Omeprazole-Containing Products for Relief of Frequent Heartburn (MK-0764A-036)
This study will evaluate a single ingredient product (omeprazole 20 mg) with a combination product capsule (omeprazole 20 mg + sodium bicarbonate 1100 mg) in participants with frequent heartburn.
- Trial name
- NCT01587885
- Testing
- Omeprazole 20 mg + Sodium Bicarbonate 1100 mg, Omeprazole 20 mg
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Volunteers
Drug Interaction With Proton Pump Inhibitors for Nifedipine ER Tablets
The purpose of this study is to measure the amount of study drug present in blood after being administered a generic version of nifedipine extended-release tablets, 60 mg (Valeant Pharmaceuticals, LLC) and brand-name version…
- Trial name
- NCT03100838
- Testing
- Nifedipine 60 MG Extended Release Oral Tablet, omeprazole/sodium bicarbonate, SmartPill (TM)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Nephropathy
A Prospective, Randomized TrialComparing Oral N-Acetylcysteine and Intravenous Sodium Bicarbonate
The purpose of this study is to compare the efficacy of oral N-acetylcysteine and intravenous sodium bicarbonate for the prevention of Contrast-Induced Nephropathy (CIN) after cardiac catheterization.
- Trial name
- PROTECt (NCT00579995)
- Testing
- Oral N-Acetylcysteine, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Complicated Pleural Effusion/ Empyema
Effectiveness and Safety of Sodium Bicarbonate Pleural Lavage in the Treatment of Complex Pleural Effusion
The goal of this clinical trial is to evaluate the safety and efficacy of sodium bicarbonate pleural lavage in treating complex pleural effusion in adult.
- Trial name
- SAPLIC (NCT06734481)
- Testing
- Sodium bicarbonate pleural lavage, Saline pleural lavage
- Where
- China
- Volunteers
- 260 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Kidney Failure, Acute, Renal Replacement Therapy
Use of Bicarbonate to Reduce the Incidence of Acute Renal Failure After Cardiac Surgery
The purpose of this study is to determine if the incidence of acute renal failure (ARF) in high risk patients who undergo coronary artery bypass grafting (CABG) is reduced by treating patients in the perioperative period with…
- Trial name
- NCT00484354
- Testing
- Sodium bicarbonate, Normal saline, Bicarbonate
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Wake Forest University Health Sciences
Hypertension
Comparison on Blood Pressure Effect of an Equivalent Sodium Intake, With Different Nature, for Hypertensive Subjects
Numerous large-scale epidemiological studies have made it possible to establish a link between the average consumption of table salt (sodium chloride) and blood pressure figures.
- Trial name
- SODIVASC-II (NCT05108402)
- Testing
- Phenotyping, Drug intake
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Clermont-Ferrand