Clinical trials: Smoking Cessation
Smoking Cessation
Nicotine Replacement Therapy and Cardiovascular Disease
The aim of this study is to compare the cardiovascular disease event rate in smokers undertaking pharmacologically unaided smoking cessation attempts (the non-exposed group) with the event rate in smokers attempting smoking…
- Trial name
- NCT02195739
- Where
- United Kingdom
- Volunteers
- 61,050 people, healthy volunteers welcome
- Sponsor
- Research in Real-Life Ltd
Smoking Cessation, Motivation
Mating-EFT Smoking Cessation Intervention
The current proposal aims to develop and establish the effectiveness of a novel behavioral smoking cessation intervention. Previous research has shown that having smokers engage in episodic future thinking (EFT) about specific…
- Trial name
- NCT03431324
- Testing
- Episodic Future Thinking about Mating Opportunities, Targeted Mating-EFT Intervention
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Smoking Cessation, Tobacco Dependence
De-nicotinised Cigarettes Study
The aim of this study is to determine if using a behavioural replacement for smoking (de-nicotinised cigarettes; DNCs), in addition to standard treatment during the first two weeks after the target quit date, can reduce urges to…
- Trial name
- Denic (NCT01250301)
- Testing
- De-nicotinised cigarettes + standard treatment, Standard Treatment
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Smoking Cessation
Early Health Warning Intervention in Tobacco Control
This is a multi-center, randomized, controlled intervention clinical trial. A total of 1000 current smokers with rapid decline in lung function will be recruited and equally divided into two groups, comprehensive smoking…
- Trial name
- NCT04996329
- Testing
- early health warning intervention
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking Cessation
Preliminary Test of Reactive Carrot Incentives in a Practice Quit Environment With Contingency Management Incentives
The primary aim of this study is to pilot test a novel reactive carrot approach for improving individuals' ability to stick to a "practice quit" program in a smoking cessation context.
- Trial name
- NCT05072301
- Testing
- Contingency Management, Control
- Where
- 2 sites in United States, Ukraine
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Yale University
Smoking Cessation
Promoting Smoking Cessation in the Community Via Quit to Win Contest 2013
According to the Census \& Statistics Department (2011), there are still 659,300 daily smokers (11.1%) in Hong Kong. Smoking and passive smoking kill over 7,000 people per year.
- Trial name
- NCT01928251
- Testing
- Informed early monetary incentive, Uninformed early monetary incentive
- Where
- China
- Volunteers
- 1,143 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking
Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus Placebo
The purpose of this study is to evaluate endothelial function and autonomic regulation (for example, heart rate and blood pressure) in smokers before and after short-term smoking cessation.
- Trial name
- NCT00673595
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smoking Cessation, Pregnancy
Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
The investigators propose to conduct a combined intervention that pairs SMS smoking cessation messages for patients with individualized training for OB clinicians to improve quit rates among pregnant smoking.
- Conditions
- Smoking Cessation, Pregnancy, Communication Research
- Trial name
- NCT04985903
- Testing
- Clinician Communication Intervention, 5A's lecture
- Where
- United States
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Duke University
Cancer, Gastrointestinal Cancer
Long-term Cancer Risk in the Randomised Oslo Diet and Antismoking Study
This study examines the effect of a five-year multifactorial lifestyle intervention in the Oslo diet and antismoking study on long-term cancer risk.
- Conditions
- Cancer, Gastrointestinal Cancer, Lung Cancer, Urinary Tract Cancer
- Trial name
- NCT03410641
- Testing
- Diet and antismoking advice
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Smoking Cessation
Mobile Chat Messaging for Smoking Relapse Prevention
Most smokers return to smoking (relapse) after making a quit attempt, but evidence of effective intervention to prevent relapse is scarce.
- Trial name
- NCT05370352
- Testing
- Standard smoking cessation treatment, Personalised chat messaging, SMS text messaging
- Where
- 2 sites in Hong Kong
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
E Cigarette Use
Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users
This study aims to investigate the acute effects of a circuit breathing intervention on nicotine withdrawal symptoms and respiratory parameters among youth who use e-cigarettes.
- Trial name
- NCT07886099
- Testing
- Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Tobacco Use Disorder
Behavioral Smoking Cessation Treatment - 1
Our primary goal is to examine the effectiveness of a multi-factor maintenance treatment strategy in promoting longer-term smoking abstinence.
- Trial name
- NCT00110825
- Testing
- Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Smoking Cessation
Integrated Smoking Cessation Treatment for Low Income Community Corrections
This study recruited cigarette smokers under supervision in community corrections (e.g., probation, parole, drug courts, etc.) in the Birmingham, Alabama area.
- Trial name
- NCT01257490
- Testing
- counseling vs. advice
- Where
- United States
- Volunteers
- 689 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Forensic Psychiatric Patients, Cardio Vascular Disease
Improving Lifestyle Habits and Metabolic Health in Forensic Psychiatric Patients
Background:People in compulsory forensic psychiatric care experience high rates of metabolic syndrome, cardiovascular disease, and related lifestyle risk factors, yet structured preventive health interventions are uncommon in…
- Conditions
- Forensic Psychiatric Patients, Cardio Vascular Disease, Health Promotion, Forensic Mental Health
- Trial name
- FOR-HEALTH (NCT07157813)
- Testing
- Structured Health Dialogue
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Smoking Cessation, Harm Reduction
Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT
This study will determine whether a range of products along the reduced-risk continuum can reduce smoke exposure for individuals who fail to quit smoking using current medically approved nicotine replacement therapy (NRT)…
- Trial name
- NCT06088862
- Testing
- Nicoderm, Nicorette 4Mg Chewing Gum, Nicorette Lozenge Product
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Rose Research Center, LLC
Tobacco Use Cessation
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
This study will evaluate the comparative effectiveness of three smoking cessation therapies: mobile health (mHealth) application iCanQuit, mHealth application iCanQuit + Motiv8, and the Florida quit line.
- Trial name
- PROMOTE-UP (NCT05415761)
- Testing
- iCanQuit, iCanQuit+Motiv8, Florida quit line
- Where
- United States
- Volunteers
- 1,332 people, healthy volunteers welcome
- Sponsor
- University of Florida
Smoking Cessation
Motivating Smokers at Outdoor Public Smoking Hotspots to Have Quit Attempt With Nicotine Replacement Therapy Sampling
Background About half of the daily smokers in Hong Kong have never tried and have no intention to quit smoking. 37.9% of daily smokers attempted to quit but failed.
- Trial name
- NCT02491086
- Testing
- Nicotine replacement therapy (NRT) sampling, Smoking cessation counseling
- Where
- Hong Kong
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Smoking Cessation
Motivating Quitline Use Among Smokers in Treatment for Substance Use Disorders
The long-term goal of this program of research is to disseminate an effective, brief computer-based intervention that can be readily integrated into Substance Use Disorders (SUD) treatment programs to motivate tobacco quitline…
- Trial name
- MI-SUD (NCT01882673)
- Testing
- Brief Computer Motivational Interviewing for Smoking Cessation, Nutrition Control
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Chronic Obstructive Pulmonary Disease
Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)
The primary aim of this study is to investigate the effects of inhaled lipopolysaccharide endotoxin (LPS) on bronchial and alveolar exhaled nitric oxide (NO) and NO metabolites and other inflammatory markers and mediators in…
- Trial name
- NCT00159289
- Testing
- Inhalation of LPS
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London