Clinical trials: Smokeless Tobacco Use
Tobacco Use Cessation, Tobacco Use Disorder
Feasibility of a Medical-Legal Partnership Model to Connect Coal Miners QuitAid
Coal miners in Central Appalachia have among the highest rates of tobacco and nicotine product (TNP) use of any occupational group and face elevated rates of lung cancer and coal workers' pneumoconiosis ("black lung").
- Conditions
- Tobacco Use Cessation, Tobacco Use Disorder, Nicotine Dependence, Smokeless Tobacco Use
- Trial name
- NCT07694492
- Testing
- QuitAid (pharmacist-delivered MTM), Nicotine Replacement Therapy (NRT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Smokeless Tobacco Cessation
Testing ANSOS for Efficacy in Multi-Tribal Urban Communities
This is a wait-list control trial to test for efficacy of the All Nations Snuff Out Smokeless (ANSOS) recreational tobacco cessation program in multi-tribal American Indian (AI) communities.
- Trial name
- NCT06566703
- Testing
- All Nations Snuff Out Smokeless, Healthy Living
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Smoking, Smoking, Cigarette
The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study
Mobile health (mHealth) will be used for early detection of oral cancer and pre-cancer lesions, and to improve awareness of oral cancer among the population and knowledge of oral cancer diagnosis among frontline health providers.
- Conditions
- Smoking, Smoking, Cigarette, Smoking, Tobacco, Betel Chewer's Mucosa
- Trial name
- NCT06535867
- Testing
- mHealth
- Where
- United States
- Volunteers
- 5,122 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Smokeless Tobacco
Influence of Authorized Smokeless Tobacco Product Modified Risk Claims II: Laboratory Assessment of Sensory and Subjective Effects
This study seeks to measure the effects of smokeless tobacco product risk messages on sensory experiences and future intentions to use.
- Trial name
- NCT07107139
- Testing
- Copenhagen group, Snus group
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study
All participants will receive the EnufSnuff.TXT scheduled gradual reduction (SGR) intervention for 6 weeks and, for those who do not reach the point of quit, includes getting randomized (like the flip of a coin) into either an…
- Trial name
- NCT06637358
- Testing
- Extended Scheduled Gradual Reduction (SGR), Quit Coach
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Duke University
Smokeless Tobacco
Nornicotine in Smokeless Tobacco as a Precursor for Carcinogen Exposure
Our goal in this study is to investigate the extent of endogenous nitrosation of nornicotine in smokeless tobacco users as a function of nornicotine content in smokeless products.
- Trial name
- NCT03998735
- Testing
- Herbal Snuff (Smokeless Tobacco)
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Smoke Exposure, Smokeless Tobacco
Effect of Passive Smoking on Functional Capacity, Cognition and Academic Performance in Primary School Children
This is an observational study that aims to understand the effects of passive smoking (secondhand smoke exposure) on children's health and development.
- Trial name
- NCT06723470
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Egyptian Chinese University
Smokeless Tobacco Cessation
Smokeless Tobacco Cessation Intervention for Firefighters
The investigators are asking professional firefighters across North Carolina to take part in focus groups to discuss the specific needs of firefighters in smokeless tobacco cessation.
- Trial name
- NCT05111041
- Testing
- #EnufSnuff.TXT- First Responder, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Smokeless Tobacco Cessation
A Text-based Reduction Intervention for Smokeless Tobacco Cessation
Participants will be randomly assigned (like the flip of a coin) to one of the two groups after completing the baseline survey. Participants have a 50% of being in either the #EnufSnuff.TXT intervention group or the Enough Snuff…
- Trial name
- NCT04315506
- Testing
- #EnufSnuff.TXT Intervention, Enough Snuff Intervention
- Where
- United States
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- Duke University
Tobacco Use, Tobacco Smoking
Comparing Nicotine Delivery, Subjective Effects, and Sensory Experiences of Tobacco Users Using Oral Nicotine Products and Electronic Cigarettes [ZYN Study]
To pilot test the appeal of non-tobacco oral nicotine products in cigarette smokers, smokeless tobacco users, and oral nicotine users.
- Conditions
- Tobacco Use, Tobacco Smoking, Cigarette Smoking, Smokeless Tobacco Cessation
- Trial name
- NCT05030194
- Testing
- Electronic Cigarette, Oral Nicotine Pouch
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Smokeless Tobacco Use
A Pilot Study Evaluating Nicotine Lozenges and Self Help
The investigators are hypothesizing that by offering both self-help materials and mailed nicotine lozenges we will be able to help increase tobacco abstinence rates among ST users, as well as decrease tobacco withdrawal.
- Trial name
- NCT00888459
- Testing
- nicotine replacement therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smokeless Tobacco, Tobacco Use Cessation
Telephone Counseling for Snuff Users
The primary objective is to evaluate the effectiveness of telephone-based counseling in promoting smokeless tobacco cessation among residents of Minnesota.
- Trial name
- NCT00265681
- Testing
- Phone counseling and written materials
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- HealthPartners Institute
Smokeless Tobacco Use, Tobacco Dependence
Novel Determinants and Measures of Smokeless Tobacco Use: Study 1
The extent of toxicity varies considerably across different brands of smokeless tobacco (ST) products and data suggest that greater toxicity may result in greater health risks.
- Trial name
- NCT01067586
- Where
- 3 sites in United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokeless Tobacco Cessation
Nicotine Lozenges and Assisted Self-help for Smokeless Tobacco Cessation
This research study will determine if using a combination of 4-mg nicotine lozenges, self-help materials, and/or telephone tobacco cessation counseling will help smokeless tobacco users stop using tobacco.
- Trial name
- LASH (NCT01341938)
- Testing
- Commit® nicotine lozenges (4 mg) & self-help materials, Commit® nicotine lozenges (4 mg) & phone counseling & self-help materials, Phone counseling & self-help materials
- Where
- United States
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Smokeless Tobacco, Nicotine Dependence
Treating Smokeless Tobacco Use in Rural Veterans
This is a pilot study designed in an effort to develop and improve access to effective treatments for tobacco use in rural Veterans using a tailored intervention approach.
- Trial name
- NCT02994082
- Testing
- Tailored behavioral intervention, Behavioral activation for elevated depressive symptoms, Post-cessation weight gain management
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Mark Vander Weg
Smokeless Tobacco Cessation
Addressing Tobacco Use Disparities Through an Innovative Mobile Phone Intervention
The purpose of this study is to evaluate the feasibility, acceptability and preliminary efficacy of a Scheduled Gradual Reduction (SGR) intervention via Short Message Service (SMS) text messaging plus SMS Support Messages in…
- Trial name
- NCT02613689
- Testing
- Scheduled Gradual Reduction (SGR), Text Messages
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Duke University
Smokeless Tobacco Cessation
Improvement in Knowledge and Perception About Hazards of Smokeless Tobacco
Oral cancer is a serious and growing problem in many parts of the globe. Oral cancer is the eighth most common cancer worldwide.The annual estimated incidence is around 275,000 for oral and 130,300 for pharyngeal cancers…
- Trial name
- NCT03418506
- Testing
- SMOKELESS TOBACCO AWARENESS PROGRAM
- Where
- Pakistan
- Volunteers
- 1,327 people
- Sponsor
- Aga Khan University
Smokeless Tobacco
Human Laboratory Study of Smokeless Tobacco Products
With the advent of restrictions on public smoking, the tobacco industry has introduced a variety of novel smokeless tobacco products (NSTP) to allow continued tobacco use.
- Trial name
- NCT01100216
- Testing
- Nicotine Lozenge, Stonewall Dissolvable Tobacco Pieces, Camel Snus Frost
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokeless Tobacco Use
Highdose Nicotine Patch Therapy for Smokeless Tobacco Use
Smokeless tobacco use ("chewing") is associated with negative health effects. To date, no medications have been shown to help chewers quit long-term.
- Trial name
- NCT00939029
- Testing
- nicotine replacement therapy (nicotine patches)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Smokeless Tobacco Use
Nicotine Lozenges for Treatment of Smokeless Tobacco Addiction
This study will be a randomized, blinded, placebo-controlled two-group clinical trial. The independent variable is treatment assignment (active 4-mg nicotine lozenge vs.
- Trial name
- NCT00392379
- Testing
- Nicotine Lozenges
- Where
- 2 sites in United States
- Volunteers
- 270 people
- Sponsor
- Mayo Clinic