Clinical trials: Sleep Apnea
Obstructive Sleep Apnea (OSA)
Evaluation of the Diagnostic Capacity of a Smart Mattress Versus Conventional Polysomnography
This project aims to develop and evaluate an innovative, non-invasive diagnostic system based on a smart mattress for detecting obstructive sleep apnea (OSA), as well as assessing overall sleep quality and identifying periodic…
- Trial name
- NCT07432919
- Testing
- Integrated polysomnographic assessment with smart mattress.
- Where
- 2 sites in Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
OSA - Obstructive Sleep Apnea
Evaluation of a Wearable PAP Device in a Tethered Configuration for the Treatment of Obstructive Sleep Apnoea.
Each participant will wear a wearable PAP device, tethered to a released PAP device for up to 7 nights. Objectives include collecting and evaluating participants feedback on seal, comfort and usability of the wearable PAP device.
- Trial name
- NCT07420140
- Testing
- Positive Airway Pressure
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea Syndrome
Retinal Vascular Network and Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSA) is thought to lead to systemic vascular lesions that may be preceded by early microvascular lesions in the eyes and in particular in the retina.
- Trial name
- ORNET (NCT03979001)
- Testing
- complete ophthalmological examination
- Where
- France
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Sleep Apnea
Spanish Registry of Patients With Sleep Apnea and Daytime Sleepiness
Multicenter, observational and prospective study, in which patients referred to the sleep unit with suspected apnea will be recruited obstructive sleep.
- Trial name
- HYPNOSA (NCT06514482)
- Testing
- Diagnosis
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospital San Pedro de Logroño
Obstructive Sleep Apnea of Adult
A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea
Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat tissue.
- Trial name
- NCT03307330
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obstructive Sleep Apnoea (OSA), Hypoventilation Syndrome
Sleep-disordered Breathing Database
The goal of this study is to collect clinical data on patients who have had a sleep study and are given a diagnosis of a sleep related breathing disorder such as obstructive sleep apnoea.
- Trial name
- NCT07402603
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Obstructive Sleep Apnea of Child
Diaphragm Ultrasound İn Children With OSAS
This is a prospective observational study evaluating perioperative diaphragmatic function by ultrasonography in children aged 1-12 years undergoing elective surgery under general anesthesia.
- Trial name
- NCT07380321
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Opioids, Obstructive Sleep Apnea (OSA)
Impacts of Opioids on Respiratory Drive During Sleep
The investigators are studying the impact that opioids have on breathing during sleep in healthy participants and those diagnosed with obstructive sleep apnea.
- Trial name
- OIRD (NCT06854211)
- Testing
- Morphine p.o.
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation
The purpose of this study is to determine if the treatment of Obstructive sleep apnea (OSA) by hypoglossal nerve stimulation (HGNS) will alter glucose metabolism.
- Trial name
- NCT06317701
- Testing
- Hypoglossal Nerve Stimulation (HGNS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Obesity & Overweight, Pediatric Obesity
Ultrasound Assessment of Tongue Characteristics in Children and Adolescents With Obesity
This longitudinal observational study aims to validate ultrasound-based tongue markers related to tongue characteristics, including fat accumulation, morphologic and mechanical properties of the tongue in children and adolescents…
- Conditions
- Obesity & Overweight, Pediatric Obesity, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07370350
- Testing
- Submental ultrasound
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole Bruxelles-Brabant
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Post Acute Sequelae of SARS CoV 2 Infection, Obstructive Sleep Apnea
Predictors of Post-COVID-19 Clinical and Cognitive Consequences
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients.
- Trial name
- SCLC (NCT06291870)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obstructive Sleep Apnea
Mechanisms of Upper Airway Obstruction
The current study is designed to examine underlying mechanisms of action of lingual muscles in the maintenance of airway patency during sleep.
- Trial name
- DISE-CAD (NCT04322097)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Disordered Breathing (SDB)
Comprehensive Care of Sleep Disordered Breathing
The Comprehensive Care of Sleep Disordered Breathing study (Care-SDB) is a prospective, multi-center, registry-based cohort study designed to investigate the integrated management of sleep-disordered breathing (SDB).
- Trial name
- Care-SDB (NCT07339371)
- Testing
- Clinical Management for SDB
- Where
- China
- Volunteers
- 11,100 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Hypertension (HTN), Sleep Apnea Syndrome, Obstructive
A Cohort Study on Increasing Blood Pressure Benefits in Sleep Apnea Patients After CPAP Treatment
Research Title "Quadruple-Blind Randomized Controlled Trial of the Effect of CPAP on Blood Pressure in Patients with Sleep Apnea" Why are we conducting this study? Sleep apnea (OSA) is very common, affecting approximately one in…
- Trial name
- NCT07357272
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beijing Anzhen Hospital
Snoring, Sleep Disturbances
Evaluating Sleep Quality With Emerging Technologies
To investigate the sleep quality of the adult orthodontic patient population at the Case Western Reserve University School of Dental Medicine using the NOSE Questionnaire, STOP-BANG Questionnaire, SleepCycle app, and Belun Ring.
- Conditions
- Snoring, Sleep Disturbances, Hypoxia, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT06900530
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Sleep Apnea, Obstructive, Larynx
Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea
This is a prospective double blinded randomized crossover controlled trial aiming at validating the measurement of laryngopharyngeal mechanosensitivity in patients with suspected OSA using a recently developed laryngopharyngeal…
- Conditions
- Sleep Apnea, Obstructive, Larynx, Sensory Disorder
- Trial name
- NCT03109171
- Testing
- Laryngopharyngeal sensory test
- Where
- 2 sites in Colombia
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Fundación Neumologica Colombiana
Sleep-Disordered Breathing, Glucose Intolerance
Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing
Sleep disordered breathing is associated with impaired glucose tolerance and incident diabetes. Nocturnal hypoxemia is a potential stimulus of glucose intolerance.
- Trial name
- NCT05462834
- Testing
- Compressed Air, Supplemental Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obstructive Apnea
Comparison of a Demand Oxygen Delivery
Conducting a randomized control trial of oxygen in children with Down syndrome to treat moderate to severe obstructive sleep apnea.
- Trial name
- DOSA (NCT06609694)
- Testing
- Portable oxygen concentrator Inogen G5 model
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mild Cognitive Impairment, Obstructive Sleep Apnea
Evaluation of Trazodone in OSA-MCI
Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disease. Before progressing to AD, individuals may experience mild cognitive impairment (MCI).
- Trial name
- NCT05209035
- Testing
- Trazodone
- Where
- Hong Kong
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong