Clinical trials: Sleep Apnea, Central
Sleep Apnea, Obstructive, Sleep Apnea
Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea
Drug-induced sleep endoscopy (DISE) is the most used technique for identifying the obstruction site associated with obstructive sleep apnea (OSA).
- Conditions
- Sleep Apnea, Obstructive, Sleep Apnea, Sleep Apnea Syndromes, Apnea
- Trial name
- NCT04729478
- Testing
- Drug-induced sleep endoscopy, Natural sleep endoscopy
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- ethisch.comite@uza.be
Chronic Kidney Disease, Obstructive Sleep Apnea
Nocturnal Blood Pressure - Central and Peripheral 24-h Blood Pressure in Chronic Kidney Disease.
A new study have shown that high nighttime blood pressure (BP) and/or non-dipping (lack of fall in blood pressure during nighttime) is a strong predictor for the risk of cardiovascular disease and mortality in patients with…
- Trial name
- NOSA (NCT01951196)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Erling Bjerregaard Pedersen
Stroke, Transient Ischemic Attack
SLEep APnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke
Obstructive sleep apnea (OSA) is common after stroke/TIA and, left untreated, is associated with recurrent vascular events, poor functional outcomes, and long-term mortality.
- Conditions
- Stroke, Transient Ischemic Attack, Obstructive Sleep Apnea
- Trial name
- SLEAP SMART (NCT02454023)
- Testing
- Portable sleep monitor (ApneaLink Air), In-laboratory polysomnography
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Sunnybrook Health Sciences Centre
Ischemic Stroke, Sleep Apnea Syndrome
Screening and Treatment of SAHS in Patients With Acute Ischemic Stroke
Ischemic stroke is a kind of common disease with great harm. In acute stage of stroke there is sharply increasing morbidity of sleep apnea hypopnea syndrome.
- Trial name
- SAHS (NCT02029183)
- Testing
- Bi level positive pressure ventilation, bi-level positive airway pressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Obstructive Sleep Apnea Syndrome
PADN to Treat Severe Obstructive Sleep Apnea
This project is focused on the treatment of severe obstructive sleep apnea with pulmonary artery denervation (PADN). Although it has now been proved that continuous positive airway pressure (CPAP) is the primary treatment for…
- Trial name
- PADN-OSA (NCT02687477)
- Testing
- Pulmonary Arterial Denervation
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Pediatric Sleep Disordered Breathing, Obstructive Sleep Apnea
Pediatric/Adolescent WatchPAT 400 Reliability Pilot Study
The goal of this clinical trial is to learn whether a newer sleep-testing device gives results that closely match the standard overnight sleep study, in children and adolescents ages 6-18 who are being evaluated for possible…
- Trial name
- NCT07851402
- Testing
- WatchPAT 400
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Milton S. Hershey Medical Center
Sleep Disordered Breathing (SDB), Cerebral Palsy (CP)
Experiences of Managing Sleep Disordered Breathing in Children With Cerebral Palsy.
Cerebral palsy (CP) refers to a non-progressive movement disorder, which occurs due to damage to the developing brain around the time of birth.
- Conditions
- Sleep Disordered Breathing (SDB), Cerebral Palsy (CP), Respiratory Support
- Trial name
- QualSDB_CP (NCT06753370)
- Where
- 2 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of Edinburgh
Chronic Heart Failure, Central Sleep Apnea
French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS)
The purpose of FACE study is to provide in routine practice complementary long-term data on the mortality and morbidity of Chronic Heart Failure (CHF) patients with Central Sleep Apnea eligible for Adaptative Servo-Ventilation…
- Trial name
- FACE (NCT01831128)
- Testing
- ASV Treatment
- Where
- 18 sites in France
- Volunteers
- 509 people
- Sponsor
- ResMed
Central Sleep Apneas Syndrome, Heart Failure
PAC-IC-SAS Pilot Study - Central Sleep Apneas Syndrome and Ventricular Function
The aim of this clinical trial is to evaluate the effect of an early treatment of sleep-disordered breathing by adaptive servo-ventilation in heart failure patient following coronary artery bypass graft surgery or other coronary…
- Conditions
- Central Sleep Apneas Syndrome, Heart Failure, Coronary Artery Bypass Graft Surgery or Other Coronary Reperfusion
- Trial name
- NCT01741337
- Testing
- Adaptive servo-ventilation post-operative treatment for 6 months
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Obstructive, Sleep Apnea, Central
Sparkle Respiratory Effort Validation
This study has been developed in order to demonstrate the validity of the Sparkle respiratory effort signal.
- Trial name
- NCT04630639
- Testing
- Sparkle
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philips Clinical & Medical Affairs Global
Sleep Apnea, Mixed Central and Obstructive Sleep Apnea
ESS as a Diagnosis Resource Aid of the Syndrome of Obstructive Sleep Apnea
The aim of this study was to analyze the effectiveness of the Epworth's sleepiness scale as a recourse aid in the diagnosis of the syndrome of obstructive sleep apnea.
- Conditions
- Sleep Apnea, Mixed Central and Obstructive Sleep Apnea, Sleep-Disordered Breathing
- Trial name
- NCT00989885
- Testing
- Questionnaire and polysomnography
- Where
- Brazil
- Volunteers
- 475 people
- Sponsor
- Fortaleza University
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Malocclusion
Multi-disciplinary Diagnosis and Treatment Process and Evaluation System for Children With Sleep Disordered Breathing and Malocclusion
The aim of this study is to compare the efficacy and safety of drug therapy, tonsillar adenoidectomy only, orthodontic treatment only and tonsillar adenoidectomy plus orthodontic treatment in children with obstructive sleep apnea…
- Trial name
- NCT03451318
- Testing
- Mometasone Furoate Nasal Spray, tonsillar adenoidectomy, Maxillary expander plus Twin-Block
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Shanghai Stomotological Hospital
Central Sleep Apnea, Secondary
Effect of Acetazolamide on Central Sleep Apnea Related to Opium Consumption
Acetazolamide improves central sleep apnea related to opium consumption.
- Trial name
- NCT02371473
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Sleep Apnea, Obstructive
A Study to Assess the Effect of Seltorexant Compared to Placebo on Respiration During Sleep in Adult Participants With Obstructive Sleep Apnea
The purpose of this study is to evaluate the effect of multiple doses of seltorexant compared with placebo on respiration during sleep in adult participants with mild to moderate obstructive sleep apnea.
- Trial name
- NCT03796026
- Testing
- Seltorexant 40 mg
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- Janssen Research & Development, LLC
Obstructive Sleep Apnea Syndrome
Telemedicine in Sleep Breathing Disorders: a Multicenter Study.
In recent years medicine has been enhanced by the incorporation of technological innovations from areas as diverse as cell biology, biochemistry, genetics, biophysics and bioengineering.
- Trial name
- NCT01716676
- Testing
- Telemedicine CPAP monitoring (webpage and televisit), Standard CPAP monitoring
- Where
- Spain
- Sponsor
- Hospital Clinic of Barcelona
Excessive Daytime Sleepiness, Obstructive Sleep Apnea
Solriamfetol's Effect on Cognitive Health in Apnea Participants During a Randomized Placebo-controlled Study
The purpose of study JZP110-405 is to determine whether solriamfetol is effective at improving cognitive function in participants with excessive daytime sleepiness (EDS) associated with obstructive sleep apnea (OSA) plus impaired…
- Conditions
- Excessive Daytime Sleepiness, Obstructive Sleep Apnea, Impaired Cognitive Function
- Trial name
- SHARP (NCT04789174)
- Testing
- Solriamfetol
- Where
- 28 sites in United States, Canada and 4 more
- Volunteers
- 59 people
- Sponsor
- Axsome Therapeutics, Inc.
Obstructive Sleep Apnea
Treatment of Obstructive Sleep Apnea (OSA) With the da Vinci® SP™ Surgical System
It is a prospective, single center, single-arm clinical study to enroll a maximum of 25 subjects.
- Trial name
- NCT04795817
- Testing
- Transoral Robotic Surgery
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Intuitive Surgical
Obstructive Sleep Apnea
Long-term CPAP Effect with Obstructive Sleep Apnea: a Telemedicine-based
we hypothesize that long-term CPAP could results in increase weight and muscle composite by changing intake content and hormone and the effect was influenced by presence of CVD, social jet lag, and CPAP compliance.
- Trial name
- MSLS-LT (NCT06738940)
- Testing
- CPAP
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Central Sleep Apnea, Complex Sleep Apnea
Registry on the Treatment of Central and Complex Sleep-Disordered Breathing With Adaptive Servo-Ventilation
Phase 1: The European ASV Registry (short name) will investigate the use of Adaptive Servo-Ventilation in non-heart failure conditions.
- Conditions
- Central Sleep Apnea, Complex Sleep Apnea, Obstructive Sleep Apnea, Mixed Sleep Apnea
- Trial name
- READ-ASV (NCT03032029)
- Testing
- Adaptive Servo-Ventilation
- Where
- 29 sites in Denmark, France and 4 more
- Volunteers
- 847 people
- Sponsor
- ResMed