Clinical trials: Skin Discoloration
Skin Resurfacing
A Phase 4 Clinical Study to Investigate the Effectiveness and Safety of Skin Resurfacing
This study is a prospective, post-marketing (Phase 4) non-registrational single-arm, open-label, multicenter study.
- Trial name
- NCT07214272
- Testing
- Fraxel® FTX Laser System
- Where
- 5 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Dental Diseases
Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia
The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years.
- Trial name
- SMILE (NCT06506734)
- Testing
- Questionnaires
- Where
- 9 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Toulouse
Skin Manifestations
Tolerability and Efficacy of Anti-Aging Treatment Regimen in Subjects With Photodamage
The subjects will use the test skincare products. This is a full face, twice daily application study, with digital photos and expert grader evaluations at Baseline, 4 and 8 week periods.
- Trial name
- NCT02422836
- Testing
- Three Product Anti-Aging Treatment Regimen
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- US CosmeceuTechs, LLC
Obstructive Sleep Apnea, Vasovagal Syncope
Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms.
The goal of this prospective cohort study is to study patients referred for sleep study by in-lab polysomnography in the Jordan University Hospital and the Jordan Hospital or with an at-home sleep study kit.
- Conditions
- Obstructive Sleep Apnea, Vasovagal Syncope, Smoking, Acanthosis Nigricans
- Trial name
- VasOSA (NCT06331819)
- Testing
- In-lab polysomnography, Continuous positive airway pressure, Home sleep study device
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- Jordan Collaborating Cardiology Group
Onychomycosis of Toenails
Efficacy and Safety of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01302119
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 32 sites in United States, Canada
- Volunteers
- 604 people
- Sponsor
- Pfizer
Onychomycosis of Toenails
Efficacy and Safety Evaluation of AN2690 Topical Solution to Treat Onychomycosis of the Toenail
The purpose of this study is to determine whether AN2690 topical solution is a safe and effective treatment for onychomycosis of the toenail.
- Trial name
- NCT01270971
- Testing
- AN2690 Topical Solution, 5%, Solution Vehicle
- Where
- 27 sites in United States
- Volunteers
- 594 people
- Sponsor
- Pfizer
Onychomycosis
A Clinical Investigation on Early Visible Effects of Application of K101 During 8 Weeks on Discoloured and Deformed Nails Resulting From Onychomycosis
The purpose of this study is to further evaluate and document early visible effects on nail appearance of topical K101.
- Trial name
- NCT01180491
- Testing
- K101 nail solution
- Volunteers
- 75 people
- Sponsor
- Moberg Pharma AB
Poikiloderma of Civatte, Dyschromia
Study of the 532 nm KTP Laser for the Treatment of Poikiloderma of Civatte
This study will evaluate the safety and efficacy of the Excel V 532 nm KTP laser for the treatment of dyschromia of the neck and/or chest (poikiloderma of Civatte).
- Conditions
- Poikiloderma of Civatte, Dyschromia, Pigmentation Disorders, Telangiectasia
- Trial name
- NCT01491620
- Testing
- 532 nm KTP laser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Cutera Inc.
Image Quality, Skin Discoloration
Lower Fluorescein Sodium Dose on Confocal Laser Endoscopy Image Quality and Yellow Discoloration of the Skin
This study was to test an appropriate dose of fluorescein sodium which can provide high image quality to ensure endoscopy examination and have no yellow dye in the skin by a randomized blinded controlled trial.
- Trial name
- NCT02519920
- Testing
- fluorescein sodium 0.01ml/kg, fluorescein sodium 0.02ml/kg, fluorescein sodium 0.05ml/kg
- Where
- China
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Shandong University
Photoaging
Trial Evaluating Both Tolerability and Improvement for Signs of Facial Photoaging, Discoloration, and Texture in Adult Females of All Skin Types by Combining a Placebo Moisturizer and Non-ablative Laser.
This is a phase 4 trial evaluating the clinical effect of combining a placebo moisturizer and non-ablative laser to improve procedural outcomes in patients with facial dyschromia.
- Trial name
- NCT06090071
- Testing
- LaseMD Laser, Sciton Laser, Phyto A+ Brightening Treatment
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Austin Institute for Clinical Research
Dyschromia
Histological Study to Evaluate Skin Changes After PicoWay® 1064 nm and 532nm Picosecond Fractional Laser Treatment
This is an open-label, two-arm, histological evaluation study. Subjects in this study will be assigned to Arm 1 or Arm 2, taking into account skin type, to receive PicoWay fractional treatment: Arm 1: 532nm hand-piece Arm 2…
- Trial name
- NCT02700204
- Testing
- PicoWay 532nm fractional treatment, PicoWay 1064nm fractional treatment
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Vitiligo, Pigmentation
Randomized, Split-body, Single-blinded Clinical Trial of NB-UVB Treatment for Vitiligo
The objective of this study is to assess the effectiveness and safety of narrowband-ultraviolet B (NB-UVB) treatment in adult subjects with vitiligo.
- Conditions
- Vitiligo, Pigmentation, Dyschromia
- Trial name
- NCT02506101
- Testing
- narrow-band ultraviolet B phototherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Skin Barrier to Water Loss, Skin Health
Apple Peptide Complex for Post-Surgical and Aesthetic Skin Recovery
This clinical study evaluates a topical botanical formulation for supporting skin recovery following invasive and non-invasive aesthetic procedures.
- Conditions
- Skin Barrier to Water Loss, Skin Health, Skin Discoloration, Skin Irritation
- Trial name
- APC-SKIN (NCT07807085)
- Testing
- Apple Peptide Complex Post-Aesthetic Care Protocol
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Grow Out Oils Clinical Aromatherapy Company
Dyschromia, Photodamaged Skin
Safety and Efficacy Study for Various Skin Conditions
Characterizing safety and efficacy of Halo Laser Treatment for Various Skin Conditions.
- Trial name
- NCT02693054
- Testing
- HALO
- Volunteers
- 34 people
- Sponsor
- Sciton
Wrinkle, Photoaging
Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging
The intended use of the radiofrequency and microneedling devices used in this study is to assess the efficacy and safety of paired treatment for the treatment of facial aging.
- Conditions
- Wrinkle, Photoaging, Dyschromia
- Trial name
- NCT05388604
- Testing
- RF device, Microneedling device
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Cynosure, Inc.