Clinical trials: Skin Aging
Skin Aging
Ultraformer MPT Combined With Fractional CO2 Versus Fractional CO2 Alone for Facial Rejuvenation
This pilot study compares fractional CO2 laser resurfacing alone with the same laser combined, in the same session, with micro-focused ultrasound (Ultraformer MPT) for signs of facial skin aging in women aged 50 to 65.
- Trial name
- ULTRA-CO2 (NCT07896512)
- Testing
- Ultraformer MPT, SmartXide Tetra Pro fractional CO2 laser
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Clinique Face MD
Aging, Skin Health
The Effects of Cosmetic Acupuncture
The study recruited 40 subjects and divided them into an intervention group and a waiting list group in a 1:1 ratio using a randomized controlled trial.
- Trial name
- NCT06952959
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Photoaging, Skin Aging
AI-Personalized Skincare Regimen for Facial Photoaging in Women
The goal of this clinical study was to learn whether a skincare regimen personalized by an artificial intelligence (AI) skin-analysis tool improves signs of facial skin aging in women aged 35 to 65 with mild-to-moderate facial…
- Trial name
- NCT07879833
- Testing
- AI-personalized skin longevity regimen
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- MDalgorithms Inc.
Skin Ageing, Healthy Ageing
Effects of a Multi-Targeted Oral Supplement on Skin, Hair, Sleep, Energy, Cognition, Libido and Epigenetic Biological Clock Age
This study evaluated the effects of a daily oral supplement regimen (Advanced ID Brain, Heart and Eye Omega Gel Capsules taken with Advanced ID Longevity and Collagen Complex Powder) on measures of skin condition, hair, sleep…
- Conditions
- Skin Ageing, Healthy Ageing, Effect of Oral Nutritional Supplementation on Skin, Hair, Sleep, Energy, Cognition and Sexual Wellbeing in Healthy Adults, Longevity
- Trial name
- IDF-AID-1 (NCT07827651)
- Testing
- Advanced ID
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- IDI Skincare Limited
Skin Aging
Evaluation of the Performance and Safety of the MD60000 Device in the Treatment of Skin Imperfections Due to Aging.
Here is the English translation of the summary: The Clinical Investigation Plan with code CIP-01-25 outlines a single-center, uncontrolled, single-arm clinical study sponsored by Promoitalia Group S.p.A.
- Trial name
- MD-AGE (NCT07873112)
- Testing
- MD60000
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Skin Aging, Hair and Scalp Health
CyanthOx™ Capsule Efficacy Study
The goal of this clinical trial is to learn whether daily intake of CyanthOx™80 capsules can improve skin, scalp, hair, and selected blood biomarkers in healthy adults after 12 weeks.
- Conditions
- Skin Aging, Hair and Scalp Health, Hair Loss
- Trial name
- NCT07774117
- Testing
- CyanthOx™80 Group
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chia Nan University of Pharmacy ＆ Science
Skin Aging
Randomized Trial of Combination Treatment With Sofwave and Sculptra
Evaluation of treatment on the upper arm with Sculptra and Sofwave on the same day versus Sofwave followed by Sculptra 1 month later.
- Trial name
- NCT07342452
- Testing
- Sofwave, Sculptra
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Skin Aging, Skin Quality
AnteAGE Exosomes and PEARL Multiplier With Microneedling for Facial Skin Quality
This exploratory clinical study evaluated changes in facial skin quality following a series of mechanical microneedling treatments combined with topical AnteAGE Exosomes and PEARL Multiplier and a standardized AnteAGE homecare…
- Trial name
- NCT07849205
- Testing
- Mechanical microneedling, AnteAGE Exosomes and PEARL Multiplier, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Facial Wrinkles, Skin Aging
Anti-Wrinkle Efficacy of a Syringic Acid-Containing Emulsion
This randomized, double-blind, split-face controlled study was conducted to evaluate the anti-wrinkle efficacy and safety of a Syringic acid-containing emulsion in healthy female subjects.
- Trial name
- NCT07850817
- Testing
- Synox-containing Emulsion, Control Emulsion
- Where
- South Korea
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BioSpectrum Inc
Skin Aging
A Double-Blind, Randomized, Double-Dummy, Active and Placebo-Controlled Clinical Study to Assess the Effect of an Oral Skin Supplement on Skin Health in Healthy Adults
The aim of this study is to investigate the impact of a two skin from within nutritional supplement(s) compared to placebo on skin aging biomarker changes.
- Trial name
- NCT07740824
- Testing
- Active SoftGel Supplement, Active Comparator Powder
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Skin Aging
A 56-Day Exploratory Study of NatureU® Mind Care BeautyU Caps on Skin Aging Parameters
This was a 56-day, single-center, open-label, single-arm exploratory study evaluating within-participant changes in skin-aging parameters after daily oral intake of NatureU® Mind Care BeautyU Caps in adult women.
- Trial name
- NUAA (NCT07571629)
- Testing
- NatureU® Mind Care BeautyU Caps
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- OmniSolutions Laboratory Holdings Limited
Skin Aging
Effect of Topical Sulforaphane on Skin Aging and With Ultraviolet and Visible Light Exposure
The study is to compare the expression of both keratin 16 and 17 before and after application of sulforaphane on both photoprotected and photoexposed area, and to determine whether these findings alter skin aging as well as skin…
- Trial name
- NCT03730649
- Testing
- Sulforaphane (broccoli sprout extract), UV or visible light
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Facial Skin Aging and Wrinkle Severity
Antioxidant Nutrition and Facial Exercise for Skin Aging
This randomized controlled trial will evaluate the effects of a 12-week combined antioxidant-rich nutrition and facial exercise program on skin quality and wrinkle severity in middle-aged women.
- Trial name
- NCT07792447
- Testing
- Combined Antioxidant Nutrition and Facial Exercise Program
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Facail Skin Aging
Facial Exercise and Daily Habit Modification Program for Skin Quality and Wrinkle Severity in Middle-Aged Women
This randomized controlled trial will evaluate the effectiveness of a 12-week program combining facial muscle exercises and daily habit modification for improving skin quality and reducing wrinkle severity in middle-aged women.
- Trial name
- NCT07792460
- Testing
- Facial Exercise and Daily Habit Modification Program
- Where
- Iraq
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Zakho
Aging, Dry Skin
Efficacy and Safety of a Topical Botanical Extract Formulation for Skin Aging
This is a single-center, double-blinded, placebo-controlled, split-face, prospective clinical study to evaluate the anti-ageing efficacy and safety of a topical cosmetic formulation containing a botanical extract.
- Trial name
- NCT07780799
- Testing
- Cosmetic Topical Formulation 1, Cosmetic Base of Topical Formulation 1, Cosmetic Topical Formulation 2
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- L'Oreal
Skin Aging on Face, Skin Care Dermocosmetics
Efficacy of Topical Niacinamide Riboside on the Signs of Facial Skin Aging
Niacinamide riboside (topical NR, also known as nicotinamide riboside) is an endogenous compound and a precursor (building block) to the essential cellular co-enzyme, nicotinamide adenine dinucleotide (NAD+).
- Conditions
- Skin Aging on Face, Skin Care Dermocosmetics, Skin Care, Fine Lines and Wrinkles
- Trial name
- NR-RADIANCE (NCT07774000)
- Testing
- Topical niacinamide riboside
- Where
- South Africa
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Frailty, Aging
MItochondrial Intervention for Resilience in Older Adults With Coenzyme Q10
This randomized, double-blind, placebo-controlled clinical trial will investigate whether 10 weeks of CoQ10 supplementation can improve biological resilience and functional health in community-dwelling adults aged 65 years or…
- Conditions
- Frailty, Aging, Mitochondria Health, Skin Aging
- Trial name
- MIRO-Q (NCT07772336)
- Testing
- Q10Vital® (CoQ10, ubiquinone)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana