Skin Aging, Dry SkinNCT07887841
Effects of Probiotics on Skin Health in Healthy Women
A study testing Probiotics in people with Skin Aging, Dry Skin, run by Probi AB at 1 site in United Kingdom.
Trial summary
The effect of probiotics on skin health in healthy women with dry to very dry facial skin. Read more about this study
- Who is it for?
- Ages 35 to 45 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Skin Aging, Dry Skin
- What is being tested?
- Probiotics
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 140 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Oct 2026to May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 to 45 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female, of self-reported Caucasian ethnicity, aged 35 to 45 years at the time of informed consent
- Fitzpatrick skin type II-IV
- Mean MoistureMeterSC value of ≤30 obtained at the Baseline Visit before randomisation
- Generally healthy
Who cannot join
- Significant facial dermatological condition that may interfere with study assessments
- Uncontrolled or clinically significant medical condition that may compromise participant safety or interpretation of study outcomes
- Known allergy, intolerance or hypersensitivity to any active ingredient, excipient or component of the study product or placebo
- Use of prohibited medications, nutritional supplements or cosmetic/dermatological procedures
- Current participation in another interventional clinical study, or participation in another interventional study within the previous 30 days.
- Lifestyle, skincare or cosmetic factors likely to interfere with study assessments or interfere with instrumental or imaging assessment
- Pregnant, breastfeeding or planning pregnancy during the study period.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United Kingdom1 site
Sequential Skin Ltd
Babraham, CB22 3AT
Omera Bi, PhD, +44 7852591629, omera@sequential.bio
About this study
Official title: A Randomised, Double-Blind, Placebo-Controlled Clinical Investigation to Evaluate the Effects of an Oral Probiotic Supplement in Healthy Adult Women With Clinically Dry to Very Dry Facial Skin.
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Conditions
- Skin Aging, Dry Skin
- Being tested
- Probiotics, Placebo
- Keywords
- probiotics, dry skin, wrinkles
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ProbioticsDietary supplement
Probiotics
PlaceboDietary supplement
Placebo
| Study group | Role | What they receive |
|---|---|---|
| Probiotics | Active comparator | Not described Receives: Dietary Supplement: Probiotics |
| Placebo | Placebo comparator | Not described Receives: Dietary Supplement: Placebo |
What is being measured
The primary outcome is the main question the study is designed to answer.
PRIMOS CR crow's-feet wrinkle depth
Measured: 12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Oct 2026
- Study startOct 2026 (estimated)
- Primary completionMay 2027 (estimated)
- Study completionMay 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Skin Aging, Dry SkinStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 140 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Probi AB
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07887841
- Sponsor's protocol ID
- ULP-363
- Status last verified
- Oct 2026
- First submitted
- 12 Oct 2026
- Last updated
- 21 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 21 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomised, Double-Blind, Placebo-Controlled Clinical Investigation to Evaluate the Effects of an Oral Probiotic Supplement in Healthy Adult Women With Clinically Dry to Very Dry Facial Skin.
- ClinicalTrials.gov ID
- NCT07887841
- Acronym / sponsor ID
- ULP-363
- Conditions
- Skin Aging, Dry Skin
- Keywords
- probiotics, dry skin, wrinkles
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 140 participants (estimated)
- Lead sponsor
- Probi ABIndustry (pharma, biotech, devices)
- Study start
- Oct 2026 (estimated)
- Primary completion
- May 2027 (estimated)
- Study completion
- May 2027 (estimated)
- First posted
- 21 Oct 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Probiotics | Active comparator | Dietary Supplement: Probiotics |
| Placebo | Placebo comparator | Dietary Supplement: Placebo |
Who may qualify
- Ages
- 35 to 45 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Female, of self-reported Caucasian ethnicity, aged 35 to 45 years at the time of informed consent
- Fitzpatrick skin type II-IV
- Mean MoistureMeterSC value of ≤30 obtained at the Baseline Visit before randomisation
- Generally healthy
Key exclusion criteria (7 listed)
- Significant facial dermatological condition that may interfere with study assessments
- Uncontrolled or clinically significant medical condition that may compromise participant safety or interpretation of study outcomes
- Known allergy, intolerance or hypersensitivity to any active ingredient, excipient or component of the study product or placebo
- Use of prohibited medications, nutritional supplements or cosmetic/dermatological procedures
- Current participation in another interventional clinical study, or participation in another interventional study within the previous 30 days.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ProbioticsProbiotics | Dietary supplement | Probiotics |
| PlaceboPlacebo | Dietary supplement | Placebo |
Primary outcome
PRIMOS CR crow's-feet wrinkle depth
Time frame: 12 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Probiotics in people with Skin Aging, Dry Skin, run by Probi AB at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 21 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Albert Dashi, PhD (+44 7852591629, albert@sequential.bio), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
PRIMOS CR crow's-feet wrinkle depth (time frame: 12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Oct 2026.