Clinical trials: Silicone Oil Tamponade
Retinal Detachment, Vitrectomy
Comparative Study of 1000 Centistoke Versus 5000 Centistoke Silicone Oil for Repair of Complex Retinal Detachments
The purpose of this study is to assess the retinal redetachment rates with 1000 centistoke versus 5000 centistoke silicone oil tamponade for repair of complex retinal detachments.
- Conditions
- Retinal Detachment, Vitrectomy, Proliferative Vitreoretinopathy, Diabetic Retinopathy
- Trial name
- NCT01255293
- Testing
- 1000 centistoke silicone oil, 5000 centistoke silicone oil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mid Atlantic Retina
Glaucoma
Anterior Segment Changes After Pars Plana Vitrectomy With SO Using AS-OCT
To evaluate changes in ACA induced by pars plana vitrectomy with SO 1000cs injection in vitreo-retinal surgery in phakic eyes using AS-OCT and changes in the IOP preoperatively, post-operatively and post-silicone oil evacuation.
- Trial name
- NCT06524661
- Testing
- AS-OCT after vitrectomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Choroidal Melanoma
Safety and Efficacy of Silicone Oil Tamponade for Surgical Attenuation of Radiation Damage in Choroidal Melanoma
A prospective, experimental, case series of 20 patients, with choroidal melanoma, in which pars plana vitrectomy and Silicone oil as vitreous substitute will be used as intraocular shielding for attenuating the deleterious…
- Trial name
- NCT01460810
- Testing
- 1000CsK Silicon Oil Tamponade
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Macular Holes, Vitrectomy
Postoperative Same Day Closure of Giant Macular Hole With Silicone Oil
Patients with stage 3 and 4 macular holes of size \>700 microns who underwent pars plana vitrectomy, Internal limiting Membrane peeling and silicone oil tamponade were followed at day 1 , 2 weeks and 1 month post silicone oil…
- Trial name
- GiantMH-SO (NCT06915948)
- Testing
- Macular Hole Surgery
- Where
- India
- Volunteers
- 32 people
- Sponsor
- Ahalia Foundation Eye Hospital
Diabetic Retinopathy, Retinal Detachment
Silicone Oil Versus Gas in PDR Patients Undergoing Vitrectomy
Subjects receiving 16% C3F8 gas tamponade during vitrectomy will have better visual acuity and similar postoperative complications to subjects who receive silicone oil tamponade during vitrectomy.
- Trial name
- NCT03660384
- Testing
- PPV/SO, PPV/C3F8
- Where
- Mexico
- Volunteers
- 302 people
- Sponsor
- Rush Eye Associates
Rhegmatogenous Retinal Detachment
Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment Patients
This study is a retrospective study. Patients who visited the ophthalmology clinic of the First Affiliated Hospital of Chongqing Medical University between September 1, 2024, and December 31, 2025, will be screened according to…
- Trial name
- NCT06826573
- Testing
- Intraocular pressure, retinal recovery status
- Where
- China
- Volunteers
- 65 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Hypermyopic Foveoschisis
Silicone Oil Tamponade for Vitrectomy of Hypermyopic Foveoschisis.
The purpose of this study is to explore the efficiency and safety of the surgical procedure of pars plana vitrectomy with silicone oil tamponade and without internal limiting membrane peeling for myopic foveoschisis eyes with…
- Trial name
- NCT05628909
- Testing
- PPV with SO tamponade, PPV with fovea-sparing ILMP and gas tamponade, PPV with gas tamponade
- Where
- China
- Volunteers
- 159 people
- Sponsor
- Peking University People's Hospital
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Silicone Oil or SF6 for Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is the separation of the neurosensory retina from the retinal pigment epithelium caused by the presence of a break that leads to the passage of fluid from the vitreous cavity into the…
- Trial name
- NCT05377606
- Testing
- Pars plana vitrectomy with silicone oil, Pars plana vitrectomy with SF6
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Retinal Detachment
Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade.
To examine and to compare the evolution of aqueous flare from presentation until the third postoperative month in a series of consecutive patients who underwent primary vitrectomy for rhegmatogenous retinal detachment (RRD), in 4…
- Trial name
- FLADESIL (NCT05053698)
- Testing
- Aqueous flare measurement
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Central Hospital, Nancy, France
Retinal Detachment
Duration of Silicone Oil Tamponade on Foveal and Parafoveal Thickness in Rhegmatogenous Retinal Detachment
Our study observes and analyses the influence of the duration of tamponade with silicone oil on the foveal and parafoveal thickness.
- Trial name
- siliconeoil (NCT05817630)
- Testing
- Silicone oil Tamponade for Retinal Detachment
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Dar El Oyoun Hospital
Retinal Detachment Rhegmatogenous, Vitrectomy
Influence of Tamponade on Retinal Shift in Eyes Undergoing Vitrectomy for Rhegmatogenous Retinal Detachment: A Comparison of Gas Versus Silicone Oil in a Pakistani Population
Rhegmatogenous retinal detachment (RRD) is a vision-threatening condition with an estimated incidence of approximately 1 in 10,000 individuals annually.
- Conditions
- Retinal Detachment Rhegmatogenous, Vitrectomy, Retina Disorder
- Trial name
- TARS (NCT07495319)
- Testing
- Pars plana vitrectomy
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Wardah
Retinal Detachment, Macular Edema
OCT Macula Biomarkers Before Silicone Oil Removal and Visual Outcome After Silicone Oil Removal
Silicone oil is commonly used as a temporary intraocular tamponade to support the retina during vitreoretinal surgery for complex retinal detachment and other severe retinal conditions.
- Conditions
- Retinal Detachment, Macular Edema, Silicone Oil Tamponade, Epiretinal Membrane
- Trial name
- NCT07865468
- Volunteers
- 30 people
- Sponsor
- Assiut University
Retinal Detachment
Double Endotamponade With Perfluorodecalin and Silicone Oil in Retinal Detachment Surgery.
Purpose: to assess the efficacy and safety of double tamponade versus silicone oil tamponade. Design: parallel-group study with balanced [1:1] stratified block randomization.
- Trial name
- NCT01959568
- Testing
- Vitrectomy and tamponade
- Where
- Russia
- Volunteers
- 290 people
- Sponsor
- The S.N. Fyodorov Eye Microsurgery State Institution
Silicone Tamponade
The Effect of Postural Changes on Intraocular Pressure in Silicone Oil-filled Eyes
The study was conducted to investigate how postural changes including sitting, supine, and LDP(lateral decubitus position) affect the IOP(intraocular pressure) of SO(silicone oil-filled eyes.
- Trial name
- NCT01992510
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Proliferative Diabetic Retinopathy, Tractional Retinal Detachment
Conbercept Injection in Treatment of Severe Proliferative Diabetic Retinopathy
To evaluate efficacy of different intravitreal Conbercept injection therapy in the treatment of severe proliferative diabetic retinopathy.
- Trial name
- NCT02816710
- Testing
- Conbercept
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Ruijin Hospital
ASOCT Changes After Vitrectomy and Silicone Oil Injection
Short-term Anterior Segment Changes After Pars Plana Vitrectomy (PPV) and Silicone Oil (SO) Tamponade, Anterior Segment OCT (AS-OCT) Study.
The purpose of our study is to utilize AS-OCT to analyze the anterior segment morphological changes in the early postoperative period of patients who will undergo PPV with silicone oil injection.
- Trial name
- NCT05599854
- Testing
- vitrectomy and silicone oil injection
- Volunteers
- 30 people
- Sponsor
- Assiut University
Retinal Detachment
Measurement of the Retinal Oxygen Saturaiton After Long-term Silicon Oil Tamponade
The purpose of this study is to evaluate the effects of long-term tamponade with silicone oil on retinal saturation with Oxymap.
- Trial name
- NCT02423382
- Testing
- Silicone oil removal
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Sun Yat-sen University